Interleukin-13 Receptor alpha1 Subunit
"Interleukin-13 Receptor alpha1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT to form the TYPE II INTERLEUKIN-4 RECEPTOR which has specificity for both INTERLEUKIN-4 and INTERLEUKIN-13. Signaling of this receptor subunit occurs through the interaction of its cytoplasmic domain with JANUS KINASES such as the TYK2 KINASE.
| Descriptor ID |
D053661
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.360.600.500 D12.776.543.750.705.852.420.600.800.500
|
| Concept/Terms |
Interleukin-13 Receptor alpha1 Subunit- Interleukin-13 Receptor alpha1 Subunit
- Interleukin 13 Receptor alpha1 Subunit
- Interleukin-4, 13 Receptor Shared Subunit
- Interleukin 4, 13 Receptor Shared Subunit
- Interleukin-13 Receptor alpha1 Chain
- Interleukin 13 Receptor alpha1 Chain
- Antigens, CD213a1
- CD213a1 Antigens
- IL-13Ralpha1
- CD213a1 Antigen
- Antigen, CD213a1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-13 Receptor alpha1 Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-4 [D12.776.543.750.705.852.420.360]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.360.600]
- Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.360.600.500]
- Receptors, Interleukin-13 [D12.776.543.750.705.852.420.600]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.600.800]
- Interleukin-13 Receptor alpha1 Subunit [D12.776.543.750.705.852.420.600.800.500]
Below are MeSH descriptors whose meaning is more specific than "Interleukin-13 Receptor alpha1 Subunit".
This graph shows the total number of publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in this website by year, and whether "Interleukin-13 Receptor alpha1 Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-13 Receptor alpha1 Subunit" by people in Profiles.
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A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets. Cancer Res. 2014 Sep 01; 74(17):4694-705.
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T cells redirected to interleukin-13Ra2 with interleukin-13 mutein--chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Ra1. Cytotherapy. 2014 Aug; 16(8):1121-31.
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Bone marrow-derived IL-13Ra1-positive thymic progenitors are restricted to the myeloid lineage. J Immunol. 2012 Apr 01; 188(7):3208-16.
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Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. J Biol Chem. 2011 Apr 15; 286(15):13357-69.
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Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity. J Exp Med. 2008 Sep 29; 205(10):2269-80.
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Obligatory role for interleukin-13 in obstructive lesion development in airway allografts. Am J Pathol. 2006 Jul; 169(1):47-60.
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Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells. Immunology. 2006 Sep; 119(1):54-62.
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Interactions between leukotriene C4 and interleukin 13 signaling pathways in a mouse model of airway disease. Arch Pathol Lab Med. 2006 Apr; 130(4):440-6.
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Characterization of the mouse interleukin-13 receptor alpha1 gene. Immunogenetics. 2000 Sep; 51(11):974-81.
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Requirement for IL-13 independently of IL-4 in experimental asthma. Science. 1998 Dec 18; 282(5397):2261-3.