"Acetylglucosaminidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-N-Acetylhexosaminidase that catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as MUCOLIPIDOSIS and various inflammatory disorders of muscle and connective tissue.
| Descriptor ID |
D000118
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| MeSH Number(s) |
D08.811.277.450.483.180.500
|
| Concept/Terms |
Acetylglucosaminidase- Acetylglucosaminidase
- beta-D-Acetamido-2-Deoxyglucosidase
- beta D Acetamido 2 Deoxyglucosidase
- beta-D-N-acetylglucosaminidase
- beta D N acetylglucosaminidase
- N-Acetyl-beta-D-glucosaminidase
- N Acetyl beta D glucosaminidase
- Chitobiase
- N,N-Diacetylchitobiase
- N,N Diacetylchitobiase
- N-Ac-beta-Glucosaminidase
- N Ac beta Glucosaminidase
- NAGase
- beta-N-Acetylglucosaminidase
- beta N Acetylglucosaminidase
|
Below are MeSH descriptors whose meaning is more general than "Acetylglucosaminidase".
Below are MeSH descriptors whose meaning is more specific than "Acetylglucosaminidase".
This graph shows the total number of publications written about "Acetylglucosaminidase" by people in this website by year, and whether "Acetylglucosaminidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylglucosaminidase" by people in Profiles.
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Assessment of predicted enzymatic activity of a-N-acetylglucosaminidase variants of unknown significance for CAGI 2016. Hum Mutat. 2019 09; 40(9):1519-1529.
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018; 14(8):1419-1434.
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A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cells. PLoS One. 2013; 8(6):e68060.
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Generation of an anti-NAGase single chain antibody and its application in a biosensor-based assay for the detection of NAGase in milk. J Immunol Methods. 2011 Feb 01; 364(1-2):14-20.
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A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. Diabetes. 2005 Apr; 54(4):1214-21.
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Molecular dissection of a cosmid from a gene-rich region in 17q21 and characterization of a candidate gene for alpha-N-acetylglucosaminidase with two cDNA isoforms. Mamm Genome. 1996 Sep; 7(9):686-90.
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[Effect of extracorporeal shock wave lithotripsy on renal function-an experience with the new type piezoelectric lithotripter, Therasonic]. Hinyokika Kiyo. 1990 Dec; 36(12):1403-7.
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[A study on acute renal damage from percutaneous nephrolithotomy assessed by urinary NAG and gamma-GTP activities]. Nihon Hinyokika Gakkai Zasshi. 1989 Mar; 80(3):343-8.
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Potentiation of ifosfamide neurotoxicity, hematotoxicity, and tubular nephrotoxicity by prior cis-diamminedichloroplatinum(II) therapy. Cancer Res. 1987 Mar 01; 47(5):1457-60.
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Ifosfamide-induced subclinical tubular nephrotoxicity despite mesna. Cancer Treat Rep. 1987 Feb; 71(2):127-30.