"Pentostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
| Descriptor ID |
D015649
|
| MeSH Number(s) |
D03.383.742.680.350.200.700 D13.570.230.677 D13.570.685.350.200.700
|
| Concept/Terms |
Pentostatin- Pentostatin
- Deoxycoformycin
- Co-Vidarabine
- 2'-Deoxycoformycin
- 2' Deoxycoformycin
|
Below are MeSH descriptors whose meaning is more general than "Pentostatin".
Below are MeSH descriptors whose meaning is more specific than "Pentostatin".
This graph shows the total number of publications written about "Pentostatin" by people in this website by year, and whether "Pentostatin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentostatin" by people in Profiles.
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First report of clinical response to venetoclax combination with pentostatin in T-cell-prolymphocytic leukemia (T-PLL). Leuk Lymphoma. 2020 02; 61(2):445-449.
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Long-term overall- and progression-free survival after pentostatin, cyclophosphamide and rituximab therapy for indolent non-Hodgkin lymphoma. Br J Haematol. 2019 05; 185(4):670-678.
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Pentostatin therapy for steroid-refractory acute graft versus host disease: identifying those who may benefit. Bone Marrow Transplant. 2018 03; 53(3):315-325.
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Graft-versus-host disease after radiation therapy in patients who have undergone allogeneic stem cell transplantation: two case reports. J Med Case Rep. 2016 Jul 28; 10:209.
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Chemoimmunotherapy for hairy cell leukemia. Best Pract Res Clin Haematol. 2015 Dec; 28(4):230-5.
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Pentostatin, cyclophosphamide and rituximab for previously untreated advanced stage, low-grade B-cell lymphomas. Br J Haematol. 2015 Jun; 169(6):814-23.
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Choosing a systemic treatment for advanced stage cutaneous T-cell lymphoma: mycosis fungoides and S?zary syndrome. Hematology Am Soc Hematol Educ Program. 2015; 2015:529-44.
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Relapsed Refractory BRAF-Negative, IGHV4-34-Positive Variant of Hairy Cell Leukemia: A Distinct Entity? J Clin Oncol. 2016 Mar 01; 34(7):e57-60.
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Update on the biology and treatment options for hairy cell leukemia. Curr Treat Options Oncol. 2014 Jun; 15(2):187-209.
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Sustained adenosine exposure causes lung endothelial apoptosis: a possible contributor to cigarette smoke-induced endothelial apoptosis and lung injury. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 01; 304(5):L361-70.