"Genes, erbB-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
Descriptor ID |
D018773
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MeSH Number(s) |
G05.360.340.024.340.375.500.791.295.300
|
Concept/Terms |
Genes, erbB-1- Genes, erbB-1
- Genes, erbB1
- Gene, erbB1
- erbB1 Gene
- erbB1 Genes
- erbB-1 Genes
- erbB 1 Genes
- erbB-1 Gene
v-erbB Genes- v-erbB Genes
- v erbB Genes
- v-erbB Gene
- v-erbB Oncogenes
- v erbB Oncogenes
- v-erbB Oncogene
c-erbB-1 Genes- c-erbB-1 Genes
- c erbB 1 Genes
- c-erbB-1 Gene
- EGFR Genes
- Epidermal Growth Factor Receptor Genes
- c-erbB-1 Proto-Oncogenes
- c erbB 1 Proto Oncogenes
- c-erbB-1 Proto-Oncogene
- Genes, EGFR
- EGFR Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, erbB-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-1".
This graph shows the total number of publications written about "Genes, erbB-1" by people in this website by year, and whether "Genes, erbB-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 1 | 2 |
2004 | 1 | 4 | 5 |
2005 | 3 | 1 | 4 |
2006 | 0 | 3 | 3 |
2007 | 2 | 2 | 4 |
2008 | 2 | 3 | 5 |
2009 | 0 | 1 | 1 |
2010 | 2 | 1 | 3 |
2012 | 2 | 0 | 2 |
2013 | 0 | 1 | 1 |
2015 | 0 | 4 | 4 |
2016 | 1 | 2 | 3 |
2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Genes, erbB-1" by people in Profiles.
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Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations. Clin Lung Cancer. 2019 01; 20(1):30-36.e3.
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Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing. JAMA Oncol. 2018 06 01; 4(6):838-841.
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Targeting the Gatekeeper: Osimertinib in EGFR T790M Mutation-Positive Non-Small Cell Lung Cancer. Clin Cancer Res. 2017 Feb 01; 23(3):618-622.
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Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages. Clin Cancer Res. 2017 Feb 01; 23(3):778-788.
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Comprehensive Screening of Gene Copy Number Aberrations in Formalin-Fixed, Paraffin-Embedded Solid Tumors Using Molecular Inversion Probe-Based Single-Nucleotide Polymorphism Array. J Mol Diagn. 2016 09; 18(5):676-687.
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Prognostic and Predictive Biomarkers in Colorectal Cancer: Implications for the Clinical Surgeon. Ann Surg Oncol. 2015 Oct; 22(11):3433-50.
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Predictive biomarkers in precision medicine and drug development against lung cancer. Chin J Cancer. 2015 Jul 02; 34(7):295-309.
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Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget. 2015 May 20; 6(14):12809-21.
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Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience. J Thorac Oncol. 2015 May; 10(5):768-777.
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Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial. J Thorac Oncol. 2013 May; 8(5):658-61.