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ANNA MANDALAKAS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6701 FANNIN
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    Collapse research activities and funding
    D43TW012274     (CHARURAT, MANHATTAN E)Jul 1, 2022 - Jun 30, 2027
    NIH
    Integrated Networks of Scholars in Global Health Research Training (INSIGHT)
    Role: Co-Principal Investigator
    D43TW011547     (MANDALAKAS, ANNA M)Jul 12, 2021 - Mar 31, 2026
    NIH
    Siyakhula: Growing HIV/TB Research Knowledge for Growing Healthy Kids in Eswatini
    Role: Principal Investigator
    U01GH002278     (MANDALAKAS, ANNA M)Sep 30, 2020 - Sep 29, 2025
    NIH
    Closing -TB GAPs - for people living with HIV: TB Guidance for Adaptable Patient-Centered Service
    Role: Principal Investigator
    R01AI137527     (MANDALAKAS, ANNA M)Jul 1, 2019 - Jun 30, 2024
    NIH
    Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring
    Role: Principal Investigator
    R01AI076199     (MANDALAKAS, ANNA M)Aug 1, 2007 - Jul 31, 2012
    NIH
    The Utility of Interferon-Gamma Release Assays in TB-HIV co-infected Children
    Role: Principal Investigator
    K23HD040982     (MANDALAKAS, ANNA M)Sep 4, 2001 - Jun 30, 2006
    NIH
    Cost-effective Screening in International Adoptees
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kunst H, Lange B, Hovardovska O, Bockey A, Zenner D, Andersen AB, Hargreaves S, Pareek M, Friedland JS, Wejse C, Bothamley G, Guglielmetti L, Chesov D, Tiberi S, Matteelli A, Mandalakas AM, Heyckendorf J, Eimer J, Malhotra A, Zamora J, Vasiliu A, Lange C, TBnet, Kunst H, Zenner D, Hargreaves S, Pareek M, Friedland JS, Wejse C, Bothamley G, Guglielmetti L, Chesov D, Tiberi S, Matteelli A, Heyckendorf J, Malhotra A, Zamora J. Tuberculosis in adult migrants in Europe: a TBnet consensus statement. Eur Respir J. 2025 Mar; 65(3). PMID: 39672603; PMCID: PMC11883149.
      Citations:    Fields:    
    2. Reimann M, Avsar K, DiNardo AR, Goldmann T, G?nther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, K?hler N, Mandalakas AM, Maurer FP, M?ller M, Nitschkowski D, Olaru ID, Popa C, Rachow A, Rolling T, Salzer HJF, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Terhalle E, Unnewehr M, Zielinski NJ, Heyckendorf J, Lange C. The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion. Pathog Immun. 2024; 10(1):120-139. PMID: 39911144; PMCID: PMC11792529.
      Citations:    
    3. Brehm TT, K?hler N, Grobbel HP, Welling J, Mandalakas AM, Fava V, Schurr E, Lange C. High risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered? Infection. 2025 Jan 21. PMID: 39836352.
      Citations:    Fields:    
    4. Carrero Longlax S, Koster KJ, Kamat AM, Lozano M, Lerner SP, Hannigan R, Nishiguchi T, Sheikh D, Ladki M, Portillo A, Koirala A, Patel TD, Spieler Z, Benjamin AB, Lebedev M, Ofili TU, Hutchison RW, Udeani G, Opperman LA, Neal G, Mandalakas AM, Netea MG, Arditi M, Avalos P, Grimm SL, Coarfa C, Cirillo JD, DiNardo AR. BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Open Forum Infect Dis. 2025 Jan; 12(1):ofaf007. PMID: 39872813; PMCID: PMC11770274.
      Citations:    Translation:CTClinical Trials
    5. Ness TE, Cirillo DM, Mandalakas AM. Commentary: Mixed Infection or Heteroresistance? Pediatric Tuberculosis Still the Achilles Heel of Diagnostic Tools. Pediatr Infect Dis J. 2025 Feb 01; 44(2):164-165. PMID: 39774016.
      Citations:    Fields:    
    6. Lange C, Mandalakas AM, Lillebaek T, Chesov D, Dheda K, Saluzzo F, Lange C, Mandalakas AM, Saluzzo F. Revisiting diagnostics: high priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we do not need. Clin Microbiol Infect. 2025 Mar; 31(3):312-314. PMID: 39732394.
      Citations:    Fields:    
    7. Pelzer PT, Stuck L, Martinez L, Richards AS, Acu?a-Villaordu?a C, Aronson NE, Bonnet M, Carvalho AC, Chan PC, Huang LM, Fang CT, Churchyard G, Corral-Londo?o HD, Datta M, Espinal MA, Fielding K, Fiore-Gartland AJ, Garcia-Basteiro A, Hanekom W, Hatherill M, Hill PC, Huerga H, Jones-L?pez EC, Kritski A, Mandalakas AM, Mangtani P, Martins Netto E, Mayanja H, Mazahir R, Murray M, Rangaka M, Scriba T, Singh J, Singh S, Stein CM, Vekemans J, Verhagen LM, Villalba JA, Wajja A, Watson B, White RG, Cobelens FGJ. Effectiveness of the primary Bacillus Calmette-Gu?rin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data. Lancet Microbe. 2025 Feb; 6(2):100961. PMID: 39709975.
      Citations:    Fields:    
    8. Meiwes L, Kontsevaya I, Chesov D, Kulcitkaia S, Dreyer V, Hillemann D, Dlamini Q, Williams C, Barer M, Brinkmann F, Kr?ger R, Thee S, Kay A, Mandalakas AM, Lange C, Dlamini Q, Williams C, Barer M, Brinkmann F, Kr?ger R, Thee S, Kay A. Whispers in the Wind: Face Mask Sampling for Mycobacterium tuberculosis Detection in Children With Pulmonary Tuberculosis. J Infect Dis. 2024 Dec 16; 230(6):1510-1517. PMID: 38798080; PMCID: PMC11646618.
      Citations: 1     Fields:    Translation:HumansCells
    9. Carratal?-Castro L, Munguambe S, Saavedra-Cervera B, de Haas P, Kay A, Marcy O, Nabeta P, Ssengooba W, Ghimenton-Walters E, Ac?cio S, Bonnet M, Ehrlich J, DiNardo AR, Vasiliu A, Lange C, Hermans S, Mandalakas AM, L?pez-Varela E, Garc?a-Basteiro AL, Stool4TB Global Partnership. Performance of stool-based molecular tests and processing methods for paediatric tuberculosis diagnosis: a systematic review and meta-analysis. Lancet Microbe. 2024 Nov 09; 100963. PMID: 39547244.
      Citations: 1     Fields:    
    10. Longlax SC, Nishiguchi T, Ladki M, Sheikh D, Martinez AL, Mace EM, Grimm SL, Caldwell T, Portillo Varela A, Sekhar RV, Mandalakas AM, Mlotshwa M, Ginidza S, Cirillo JD, Wallis RS, Netea MG, van Crevel R, Coarfa C, DiNardo AR. TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance. Proc Natl Acad Sci U S A. 2024 Oct 08; 121(41):e2404841121. PMID: 39348545; PMCID: PMC11474056.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    11. Amuge PM, Ndekezi D, Mugerwa M, Bbuye D, Rutebarika DA, Kizza L, Namugwanya C, Baita A, Elyanu PJ, Ntege PN, Kiragga D, Birungi C, Kekitiinwa AR, Kiragga A, Sekadde MP, Salazar-Austin N, Mandalakas AM, Musoke P. Correction: Facilitators and barriers to initiating and completing tuberculosis preventive treatment among children and adolescents living with HIV in Uganda: a qualitative study of adolescents, caretakers and health workers. AIDS Res Ther. 2024 Sep 06; 21(1):61. PMID: 39243090; PMCID: PMC11380342.
      Citations:    Fields:    
    12. Amuge PM, Ndekezi D, Mugerwa M, Bbuye D, Rutebarika DA, Kizza L, Namugwanya C, Baita A, Elyanu PJ, Ntege PN, Kiragga D, Birungi C, Kekitiinwa AR, Kiragga A, Sekadde MP, Salazar NA, Mandalakas AM, Musoke P. Facilitators and barriers to initiating and completing tuberculosis preventive treatment among children and adolescents living with HIV in Uganda: a qualitative study of adolescents, caretakers and health workers. AIDS Res Ther. 2024 Aug 29; 21(1):59. PMID: 39210349; PMCID: PMC11363537.
      Citations: 1     Fields:    Translation:Humans
    13. Hooli S, Colbourn T, Shah MI, Murray K, Mandalakas A, McCollum ED. Pulse Oximetry Accuracy in Children with Dark Skin Tones: Relevance to Acute Lower Respiratory Infection Care in Low- and Middle-Income Countries. Am J Trop Med Hyg. 2024 Oct 02; 111(4):736-739. PMID: 39106851; PMCID: PMC11448522.
      Citations:    Fields:    Translation:Humans
    14. Kay A, Lukhele B, Dlamini S, Seeger A, Dlamini P, Ndabezitha S, Mthethwa N, Steffy T, Komba L, Amuge P, Ketangenyi E, Elyanu P, Munthali A, Msekandiana A, Maldonado Y, Chiao E, Kekitiinwa A, Thahane L, Mwita L, Kirchner HL, Mandalakas AM. Predicting mortality within 1 year of ART initiation in children and adolescents living with HIV in sub-Saharan Africa: a retrospective observational cohort study. Lancet Glob Health. 2024 Jun; 12(6):e929-e937. PMID: 38762295; PMCID: PMC11149103.
      Citations:    Fields:    
    15. Martinez L, Seddon JA, Horsburgh CR, Lange C, Mandalakas AM, TB Contact Studies Consortium. Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies. Lancet Respir Med. 2024 Aug; 12(8):633-641. PMID: 38734022.
      Citations: 1     Fields:    
    16. Garcia-Basteiro AL, Ehrlich J, Bonnet M, Calnan M, Graham SM, Hermans S, Jarrett A, Lewa R, Mandalakas A, Martinez L, Migliori GB, Ong CWM, Otero L, Rangaka MX, Raviglione MCB, Seaworth B, Ssengooba W, Theron G, Trajman A, Behr MA. A Global Tuberculosis Dictionary: unified terms and definitions for the field of tuberculosis. Lancet Glob Health. 2024 May; 12(5):e737-e739. PMID: 38527468; PMCID: PMC11460053.
      Citations: 3     Fields:    
    17. Kay A, Vasiliu A, Carratala-Castro L, Mtafya B, Mendez Reyes JE, Maphalala N, Munguambe S, Mulengwa D, Ness T, Saavedra B, Bacha J, Maphalala G, Mejia R, Mtetwa G, Acacio S, Manjate P, Mambuque E, Shiba N, Kota N, Ziyane M, Ntinginya NE, Lange C, Kirchner HL, DiNardo AR, Garcia-Basteiro AL, Mandalakas AM, Stool4TB Global Partnership, Mandalakas AM. Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study. Lancet Microbe. 2024 May; 5(5):e433-e441. PMID: 38461830; PMCID: PMC11142891.
      Citations: 4     Fields:    
    18. Carratala-Castro L, Ssengooba W, Kay A, Ac?cio S, Ehrlich J, DiNardo AR, Shiba N, Nsubuga JK, Munguambe S, Saavedra-Cervera B, Manjate P, Mulengwa D, Sibandze B, Ziyane M, Kasule G, Mambuque E, Sekadde MP, Wobudeya E, Joloba ML, Heyckendorf J, Lange C, Hermans S, Mandalakas A, Garc?a-Basteiro AL, Lopez-Varela E, Stool4TB Global Partnership. A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation. BMC Infect Dis. 2024 Feb 21; 24(1):233. PMID: 38383310; PMCID: PMC10880221.
      Citations:    Fields:    Translation:HumansCellsCTClinical Trials
    19. Lange C, Vasiliu A, Mandalakas AM. Emerging bedaquiline-resistant tuberculosis. Lancet Microbe. 2023 12; 4(12):e964-e965. PMID: 37931639; PMCID: PMC11460056.
      Citations: 1     Fields:    Translation:Humans
    20. K?hler N, Vasiliu A, Mandalakas AM, Martinez L, Lange C, TBnet. Tuberculosis screening in migrants to the EU/EEA and UK. Eur Respir J. 2023 11; 62(5). PMID: 37918879; PMCID: PMC11851637.
      Citations:    Fields:    Translation:HumansPHPublic Health
    21. Gupta RK, Hamada Y, Bonnet M, Sester M, Vasiliu A, Martinez L, Ness T, Kay A, Kaufmann SHE, Lange C, Mandalakas AM. Tuberculosis prevention: current strategies and future directions. Clin Microbiol Infect. 2024 Sep; 30(9):1123-1130. PMID: 37918510; PMCID: PMC11524220.
      Citations: 1     Fields:    
    22. Vasiliu A, Altpeter E, ?gisd?ttir TR, Amerali M, Bakos ?, D'Amato S, Cirillo DM, Davidaviciene E, Demuth I, Dom?nguez J, Guthmann JP, Hatzianastasiou S, Holm LH, Herrador Z, Hribar U, Huberty C, Ibraim E, Jackson S, Jensenius M, Josefsdottir KS, Korzeniewska-Kosela M, Kuksa L, Kunst H, Muylle I, Pace-Asciak A, Petrovic G, Pieridou D, Russo G, Rzhepishevska O, Marques MS, Schmid D, Sukholytka M, Svetina P, Tyufekchieva M, Viiklepp P, Villand K, Wallenfels J, Wesolowski S, Martinez L, TBnet, K?hler N, de O?ate WA, van Crevel R, Duarte R, G?nther G, Koch A, Lienhardt C, Mahler B, Makek MJ, Normark J, Salzer HJF, Solovic I, Vasankari T, Mandalakas AM, Zenner D, Lange C. Tuberculosis incidence in foreign-born people residing in European countries in 2020. Euro Surveill. 2023 10; 28(42). PMID: 37855907; PMCID: PMC10588305.
      Citations:    Fields:    Translation:Humans
    23. Nguyen D, Ssebunya RN, Hirani K, Mandalakas A, Benjamin J, Ligon BL, Thammasitboon S. Using starling murmuration as a model for creating a global health community of practice to advance equity in scholarship. Med Teach. 2024 04; 46(4):537-544. PMID: 37756416.
      Citations:    Fields:    
    24. Sandoval M, Mtetwa G, Devezin T, Vambe D, Sibanda J, Dube GS, Dlamini-Simelane T, Lukhele B, Mandalakas AM, Kay A. Community-based tuberculosis contact management: Caregiver experience and factors promoting adherence to preventive therapy. PLOS Glob Public Health. 2023; 3(7):e0001920. PMID: 37450473; PMCID: PMC10348572.
      Citations:    
    25. Masekela R, Mandalakas AM. Pediatric Post-TB Lung Disease: Ready for Prime Time? Am J Respir Crit Care Med. 2023 04 15; 207(8):975-977. PMID: 36790380; PMCID: PMC10112449.
      Citations: 1     Fields:    Translation:Humans
    26. Gunasekera KS, Marcy O, Mu?oz J, Lopez-Varela E, Sekadde MP, Franke MF, Bonnet M, Ahmed S, Amanullah F, Anwar A, Augusto O, Aurilio RB, Banu S, Batool I, Brands A, Cain KP, Carratal?-Castro L, Caws M, Click ES, Cranmer LM, Garc?a-Basteiro AL, Hesseling AC, Huynh J, Kabir S, Lecca L, Mandalakas A, Mavhunga F, Myint AA, Myo K, Nampijja D, Nicol MP, Orikiriza P, Palmer M, Sant'Anna CC, Siddiqui SA, Smith JP, Song R, Thuong Thuong NT, Ung V, van der Zalm MM, Verkuijl S, Viney K, Walters EG, Warren JL, Zar HJ, Marais BJ, Graham SM, Debray TPA, Cohen T, Seddon JA. Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis. Lancet Child Adolesc Health. 2023 05; 7(5):336-346. PMID: 36924781; PMCID: PMC10127218.
      Citations: 1     Fields:    Translation:Humans
    27. Dom?nguez J, Boeree MJ, Cambau E, Chesov D, Conradie F, Cox V, Dheda K, Dudnyk A, Farhat MR, Gagneux S, Grobusch MP, Gr?schel MI, Guglielmetti L, Kontsevaya I, Lange B, van Leth F, Lienhardt C, Mandalakas AM, Maurer FP, Merker M, Miotto P, Molina-Moya B, Morel F, Niemann S, Veziris N, Whitelaw A, Horsburgh CR, Lange C, TBnet and RESIST-TB networks. Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement. Lancet Infect Dis. 2023 04; 23(4):e122-e137. PMID: 36868253; PMCID: PMC11460057.
      Citations: 2     Fields:    Translation:HumansCells
    28. Kay A, Mendez-Reyes J, Devezin T, Bakaya M, Steffy T, Dlamini S, Msekandiana A, Ness T, Bacha J, Amuge P, Matshaba M, Chodota M, Nyasulu P, Thahane L, Mwita L, Kekitiinwa A, DiNardo A, Lukhele B, Kirchner HL, Mandalakas A. Optimal Timing of Antiretroviral Therapy Initiation in Children and Adolescents With Human Immunodeficiency Virus-Associated Pulmonary Tuberculosis. Clin Infect Dis. 2023 01 06; 76(1):10-17. PMID: 36097966; PMCID: PMC9825818.
      Citations:    
    29. Ness TE, Meiwes L, Kay A, Mejia R, Lange C, Farhat M, Mandalakas A, DiNardo A. Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications. Microbiol Spectr. 2023 02 14; 11(1):e0226922. PMID: 36475757; PMCID: PMC9927083.
      Citations: 1     Fields:    Translation:HumansCells
    30. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Dlamini MG, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A. Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 Sep 20; 14(1):107. PMID: 36127736; PMCID: PMC9487157.
      Citations:    
    31. DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S, DZIF-TB cohort study group, Cirillo JD, Kaufmann SHE, Netea MG, van Crevel R, Mandalakas AM, Coarfa C. Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. Eur Respir J. 2022 09; 60(3). PMID: 35169026; PMCID: PMC9474892.
      Citations: 1     Fields:    
    32. Nguyen D, Thammasitboon S, Mandalakas AM. Health Disparities in Children and Adolescents Living in LMIC During COVID-19 Pandemic. Curr Trop Med Rep. 2022; 9(4):194-196. PMID: 36105113; PMCID: PMC9463048.
      Citations:    
    33. Kay AW, Ness T, Verkuijl SE, Viney K, Brands A, Masini T, Gonz?lez Fern?ndez L, Eisenhut M, Detjen AK, Mandalakas AM, Steingart KR, Takwoingi Y. Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children. Cochrane Database Syst Rev. 2022 09 06; 9:CD013359. PMID: 36065889; PMCID: PMC9446385.
      Citations:    
    34. Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox GJ, Carvalho ACC, Chan PC, Croda J, Hill PC, Lopez-Varela E, Donkor S, Fielding K, Graham SM, Espinal MA, Kampmann B, Reingold A, Huerga H, Villalba JA, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm JT, Seddon JA, Whalen CC, Garc?a-Basteiro AL, Triasih R, Chen C, Singh J, Huang LM, Sharma S, Hannoun D, Del Corral H, Mandalakas AM, Malone LL, Ling DL, Kritski A, Stein CM, Vashishtha R, Boulahbal F, Fang CT, Boom WH, Netto EM, Lemos AC, Hesseling AC, Kay A, Jones-L?pez EC, Horsburgh CR, Lange C, Andrews JR. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. Lancet Glob Health. 2022 09; 10(9):e1307-e1316. PMID: 35961354; PMCID: PMC10406427.
      Citations:    
    35. Donald P, Kaufmann S, Mandalakas AM, Lange C, Thee S. Pathogenesis of tuberculosis: the 1930 L?beck disaster revisited. Eur Respir Rev. 2022 Jun 30; 31(164). PMID: 35768133; PMCID: PMC9488810.
      Citations:    Fields:    Translation:HumansCells
    36. Huang Z, LaCourse SM, Kay AW, Stern J, Escudero JN, Youngquist BM, Zheng W, Vambe D, Dlamini M, Mtetwa G, Cranmer LM, Njuguna I, Wamalwa DC, Maleche-Obimbo E, Catanzaro DG, Lyon CJ, John-Stewart G, DiNardo A, Mandalakas AM, Ning B, Hu TY. CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study. Lancet Microbe. 2022 07; 3(7):e482-e492. PMID: 35659882; PMCID: PMC9300929.
      Citations:    Translation:HumansCells
    37. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Glenn Dlamini M, Ness T, Mejia R, Kuhns M, Dlamini S, Maphalala G, Niemann S, Mandalakas A, Kalsdorf B, Heyckendorf J, Maurer FP. Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 05 19; 14(1):52. PMID: 35585607; PMCID: PMC9118838.
      Citations: 1     Fields:    Translation:HumansCells
    38. Kay AW, Sandoval M, Mtetwa G, Mkhabela M, Ndlovu B, Devezin T, Sikhondze W, Vambe D, Sibanda J, Dube GS, Stevens RH, Lukhele B, Mandalakas AM. Vikela Ekhaya: A Novel, Community-based, Tuberculosis Contact Management Program in a High Burden Setting. Clin Infect Dis. 2022 05 03; 74(9):1631-1638. PMID: 34302733; PMCID: PMC9070808.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    39. Fennelly KP, Martinez L, Mandalakas AM. Tuberculosis: First in Flight. Am J Respir Crit Care Med. 2022 02 01; 205(3):272-274. PMID: 34905703; PMCID: PMC8886999.
      Citations:    Fields:    Translation:Humans
    40. Lange C, Kay A, Mandalakas AM. The need for effective drugs for TB prevention: set your goals high, and don?t stop till you get there. Int J Tuberc Lung Dis. 2022 02 01; 26(2):85-88. PMID: 35086616; PMCID: PMC9296677.
      Citations: 1     Fields:    Translation:Humans
    41. Kay AW, Rabie H, Maleche-Obimbo E, Sekadde MP, Cotton MF, Mandalakas AM. HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies. Pathogens. 2021 Dec 29; 11(1). PMID: 35055981; PMCID: PMC8780758.
      Citations: 1     
    42. Mtetwa G, Anabwani-Richter F, Dlamini N, Dlamini Q, Devezin T, Kay A, DiNardo A, Mandalakas A, Lukhele B. Sterilization of gowns: making the most of a scarce commodity during the COVID-19 pandemic. Public Health Action. 2021 Sep 21; 11(3):112-113. PMID: 34567985; PMCID: PMC8455021.
      Citations:    
    43. Aaby P, Behr MA, Donald PR, Netea MG, Mandalakas AM, Lange C, Kaufmann SHE. 100 years of Mycobacterium bovis bacille Calmette-Gu?rin. Lancet Infect Dis. 2022 01; 22(1):e2-e12. PMID: 34506734.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    44. Heyckendorf J, Marwitz S, Reimann M, DiNardo AR, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, Kontsevaya I, van Leth F, Mandalakas AM, Maurer FP, Olaru ID, Popa C, Rachow A, Rolling T, Rybniker J, Salzer HJF, Sanchez-Carballo P, Schaub D, Spinu V, Terhalle E, Unnewehr M, Weiner J, Goldmann T, Lange C, Avsar K, G?nther G, M?ller M, Nitschkowski D, Schuhmann M, Su?rez I. Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. Eur Respir J. 2021 09; 58(3). PMID: 33574078.
      Citations: 3     Fields:    Translation:HumansCells
    45. Thivalapill N, Simelane T, Mthethwa N, Dlamini S, Lukhele B, Okello V, Kirchner HL, Mandalakas AM, Kay AW. Transition to Dolutegravir Is Associated With an Increase in the Rate of Body Mass Index Change in a Cohort of Virally Suppressed Adolescents. Clin Infect Dis. 2021 08 02; 73(3):e580-e586. PMID: 33119739; PMCID: PMC8326552.
      Citations: 3     Fields:    Translation:Humans
    46. Ronge L, Sloot R, Du Preez K, Kay AW, Kirchner HL, Grewal HMS, Mandalakas AM, Hesseling AC. The Magnitude of Interferon Gamma Release Assay Responses in Children With Household Tuberculosis Contact Is Associated With Tuberculosis Exposure and Disease Status. Pediatr Infect Dis J. 2021 08 01; 40(8):763-770. PMID: 34050092; PMCID: PMC8277676.
      Citations:    Fields:    Translation:HumansCells
    47. Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM. Screening tests for active pulmonary tuberculosis in children. Cochrane Database Syst Rev. 2021 06 28; 6:CD013693. PMID: 34180536; PMCID: PMC8237391.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    48. Jasumback CL, Dlamini Q, Kahari J, Maphalala G, Dlamini MG, Dube GS, DiNardo A, Kirchner HL, Mandalakas A, Kay AW. Laboratory comparison of stool processing methods for Xpert? Ultra. Public Health Action. 2021 Jun 21; 11(2):55-57. PMID: 34159062; PMCID: PMC8202631.
      Citations: 2     
    49. Kontsevaya I, Lange C, Coarfa C, DiNardo AR, Gillespie SH, Hauptmann M, Leschczyk C, Mandalakas AM, Martinecz A, Merker M, Niemann S, Reimann M, Schaible UE, Scheu KM, Abel Zur Wiesch P, Heyckendorf J, Comella-Del-Barrio P, Rzhepishevska O, Schurr E. Perspectives for systems biology in the management of tuberculosis. Eur Respir Rev. 2021 Jun 30; 30(160). PMID: 34039674; PMCID: PMC9488731.
      Citations: 1     Fields:    Translation:Humans
    50. Mandalakas AM, Hesseling AC, Kay A, Du Preez K, Martinez L, Ronge L, DiNardo A, Lange C, Kirchner HL. Tuberculosis prevention in children: a prospective community-based study in South Africa. Eur Respir J. 2021 04; 57(4). PMID: 33122339; PMCID: PMC8060782.
      Citations: 3     Fields:    Translation:Humans
    51. Lange C, Chesov D, Konstantynovska O, Mandalakas AM, Udwadia Z. Sorry for the delay. Clin Microbiol Infect. 2021 07; 27(7):941-943. PMID: 33823271; PMCID: PMC8079284.
      Citations:    Fields:    Translation:HumansCells
    52. Marais BJ, Verkuijl S, Casenghi M, Triasih R, Hesseling AC, Mandalakas AM, Marcy O, Seddon JA, Graham SM, Amanullah F. Paediatric tuberculosis - new advances to close persistent gaps. Int J Infect Dis. 2021 Dec; 113 Suppl 1:S63-S67. PMID: 33716193; PMCID: PMC11849748.
      Citations: 3     Fields:    Translation:Humans
    53. DiNardo AR, Nishiguchi T, Grimm SL, Schlesinger LS, Graviss EA, Cirillo JD, Coarfa C, Mandalakas AM, Heyckendorf J, Kaufmann SHE, Lange C, Netea MG, Van Crevel R. Tuberculosis endotypes to guide stratified host-directed therapy. Med. 2021 03 12; 2(3):217-232. PMID: 34693385; PMCID: PMC8530349.
      Citations: 3     Translation:HumansCells
    54. Vonasek B, Kay A, Devezin T, Bacha JM, Kazembe P, Dhillon D, Dlamini S, Haq H, Thahane L, Simon K, Matshaba M, Sanders J, Minde M, Wanless S, Nyasulu P, Mandalakas A. Tuberculosis symptom screening for children and adolescents living with HIV in six high HIV/TB burden countries in Africa. AIDS. 2021 01 01; 35(1):73-79. PMID: 33048868; PMCID: PMC7752241.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    55. Kay AW, Thivalapill N, Skinner D, Dube GS, Dlamini N, Mzileni B, Fuentes P, Ustero P, Adams LV, Mandalakas AM. Predictors of suboptimal adherence to isoniazid preventive therapy among adolescents and children living with HIV. PLoS One. 2020; 15(12):e0243713. PMID: 33332462; PMCID: PMC7746166.
      Citations: 4     Fields:    Translation:Humans
    56. Thivalapill N, Jasumback CL, Perry SH, Dlamini L, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Kirchner HL, Mphaya J, Lukhele B, Mandalakas A, Kay AW. Predicting Sexually Transmitted Infections Among HIV+ Adolescents and Young Adults: A Novel Risk Score to Augment Syndromic Management in Eswatini. J Acquir Immune Defic Syndr. 2020 12 15; 85(5):543-552. PMID: 32947446.
      Citations:    Fields:    Translation:HumansPHPublic Health
    57. Mandalakas AM, Kay AW, Bacha JM, Devezin T, Golin R, Simon KR, Dhillon D, Dlamini S, DiNardo A, Matshaba M, Sanders J, Thahane L, Amuge PM, Ahmed S, Sekadde MP, Fida NG, Lukhele B, Chidah N, Damba D, Mhango J, Chodota M, Matsoso M, Kayabu A, Wanless RS, Schutze GE. Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa. Emerg Infect Dis. 2020 12; 26(12). PMID: 33219815; PMCID: PMC7706926.
      Citations: 4     Fields:    Translation:Humans
    58. Gatchalian SR, Agathis NT, Castillo-Carandang NT, Gunter SM, Murray KO, Mandalakas AM. Design and Evaluation of Risk Assessment Tools to Identify Pediatric Tuberculosis Infection in Bohol, the Philippines, a Low-HIV- and High-TB-Burden Setting. Am J Trop Med Hyg. 2020 11; 103(5):1818-1826. PMID: 32975174; PMCID: PMC7646812.
      Citations:    Fields:    Translation:HumansCells
    59. Lange C, Aarnoutse R, Chesov D, van Crevel R, Gillespie SH, Grobbel HP, Kalsdorf B, Kontsevaya I, van Laarhoven A, Nishiguchi T, Mandalakas A, Heyckendorf J, Reimann M, Ruhwald M, Sanchez-Carballo P, DiNardo AR, Merker M, Niemann S, K?hler N, Schwudke D, Waldow F. Perspective for Precision Medicine for Tuberculosis. Front Immunol. 2020; 11:566608. PMID: 33117351; PMCID: PMC7578248.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    60. Kay AW, Ness TE, Martinez L, Mandalakas AM. It Ain't Over Till It's Over: The Triple Threat of COVID-19, TB, and HIV. Am J Trop Med Hyg. 2020 10; 103(4):1348-1349. PMID: 32876009; PMCID: PMC7543805.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    61. Sandoval M, Swamy P, Kay AW, Alonso PU, Dube GS, Hlophe-Dlamini H, Mandalakas AM. Distinct Risk Factors for Clinical and Bacteriologically Confirmed Tuberculosis among Child Household Contacts in a High-Burden Setting. Am J Trop Med Hyg. 2020 12; 103(6):2506-2509. PMID: 32996456; PMCID: PMC7695104.
      Citations:    Fields:    Translation:HumansPHPublic Health
    62. Kay AW, Takwoingi Y, Eisenhut M, Detjen AK, Steingart KR, Mandalakas AM, Gonz?lez Fern?ndez L. Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children. Cochrane Database Syst Rev. 2020 08 27; 8:CD013359. PMID: 32853411; PMCID: PMC8078611.
      Citations: 22     Fields:    Translation:HumansCells
    63. DiNardo AR, Rajapakshe K, Nishiguchi T, Grimm SL, Mtetwa G, Dlamini Q, Kahari J, Mahapatra S, Kay A, Maphalala G, Mace EM, Makedonas G, Cirillo JD, Netea MG, van Crevel R, Coarfa C, Mandalakas AM. DNA hypermethylation during tuberculosis dampens host immune responsiveness. J Clin Invest. 2020 06 01; 130(6):3113-3123. PMID: 32125282; PMCID: PMC7260034.
      Citations: 15     Fields:    Translation:HumansCells
    64. Martinez L, Cords O, Horsburgh CR, Andrews JR, Pediatric TB Contact Studies Consortium. The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis. Lancet. 2020 03 21; 395(10228):973-984. PMID: 32199484; PMCID: PMC7289654.
      Citations: 40     Fields:    Translation:HumansCellsPHPublic Health
    65. Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR, Lange C. Challenging the management of drug-resistant tuberculosis - Authors' reply. Lancet. 2020 03 07; 395(10226):783-784. PMID: 32145791.
      Citations:    Fields:    Translation:Humans
    66. Jasumback CL, Perry SH, Ness TE, Matsenjwa M, Masangane ZT, Mavimbela M, Mthethwa N, Dlamini L, Mphaya J, Kirchner HL, Mandalakas A, Kay AW. Point-of-Care Testing to Guide Treatment and Estimate Risk Factors for Sexually Transmitted Infections in Adolescents and Young People With Human Immunodeficiency Virus in Eswatini. Open Forum Infect Dis. 2020 Mar; 7(3):ofaa052. PMID: 32190707; PMCID: PMC7071112.
      Citations: 3     
    67. Amanullah F, Bacha JM, Fernandez LG, Mandalakas AM. Quality matters: Redefining child TB care with an emphasis on quality. J Clin Tuberc Other Mycobact Dis. 2019 Dec; 17:100130. PMID: 31788571; PMCID: PMC6880125.
      Citations: 1     
    68. Murray KO, Castillo-Carandang NT, Mandalakas AM, Cruz AT, Leining LM, Gatchalian SR, PEER Health Bohol Pediatric Study Team. Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines. Emerg Infect Dis. 2019 10; 25(10):1884-1892. PMID: 31538561; PMCID: PMC6759243.
      Citations: 2     Fields:    Translation:Humans
    69. Apis V, Landi M, Graham SM, Islam T, Amini J, Sabumi G, Mandalakas AM, Meae T, du Cros P, Shewade HD, Welch H. Outcomes in children treated for tuberculosis with the new dispersible fixed-dose combinations in Port Moresby. Public Health Action. 2019 Sep 21; 9(Suppl 1):S32-S37. PMID: 31579647; PMCID: PMC6735452.
      Citations: 2     
    70. Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR, Lange C. Management of drug-resistant tuberculosis. Lancet. 2019 09 14; 394(10202):953-966. PMID: 31526739; PMCID: PMC11524526.
      Citations: 39     Fields:    Translation:HumansCells
    71. Ballif M, Kiertiburanakul S, Yotebieng M, Michael D, Sterling TR, Ngonyani KM, Mandalakas AM, Egger M, Pettit AC, Fenner L, International Epidemiology Databases to Evaluate AIDS (IeDEA) consortium, Z?rcher K, Chenal H, Grinsztejn B. Diagnosis and clinical outcomes of extrapulmonary tuberculosis in antiretroviral therapy programmes in low- and middle-income countries: a multicohort study. J Int AIDS Soc. 2019 09; 22(9):e25392. PMID: 31507083; PMCID: PMC6737289.
      Citations: 7     Fields:    Translation:Humans
    72. Lange C, Aarnoutse RE, Alffenaar JWC, Bothamley G, Brinkmann F, Costa J, Chesov D, van Crevel R, Dedicoat M, Dominguez J, Duarte R, Grobbel HP, Guglielmetti L, Heyckendorf J, Kay AW, Kirakosyan O, Kirk O, Koczulla RA, Kudriashov GG, Kuksa L, van Leth F, Magis-Escurra C, Mandalakas AM, Molina-Moya B, Peloquin CA, Reimann M, Rumetshofer R, Schaaf HS, Tiberi S, Valda J, Yablonskii PK, Dheda K, G?nther G, Sch?n T. Management of patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis. 2019 06 01; 23(6):645-662. PMID: 31315696.
      Citations: 18     Fields:    Translation:HumansCells
    73. Martinez L, Lo NC, Cords O, Hill PC, Khan P, Hatherill M, Mandalakas A, Kay A, Horsburgh CR, Zar HJ, Andrews JR, Croda J. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. Lancet Respir Med. 2019 06; 7(6):544-552. PMID: 31078497; PMCID: PMC7323920.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    74. Keating EM, Sanders J, Ngo K, Mohapi EQ, Mandalakas AM. Development of a Tool for Health Screening and Assessment in Orphanages in Lesotho. Am J Trop Med Hyg. 2019 05; 100(5):1290-1293. PMID: 30915954; PMCID: PMC6493929.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    75. Said K, Hella J, Ruzegea M, Solanki R, Chiryamkubi M, Mhimbira F, Ritz N, Schindler C, Mandalakas AM, Manji K, Tanner M, Fenner L, Utzinger J. Immunologic-based Diagnosis of Latent Tuberculosis Among Children Younger Than 5 Years of Age Exposed and Unexposed to Tuberculosis in Tanzania. Pediatr Infect Dis J. 2019 04; 38(4):333-339. PMID: 30882720.
      Citations: 5     Fields:    Translation:Humans
    76. Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, Mtetwa G, Ustero P, Maphalala G, Mandalakas AM. Evaluation of the QuantiFERON-Tuberculosis Gold Plus Assay in Children with Tuberculosis Disease or Following Household Exposure to Tuberculosis. Am J Trop Med Hyg. 2019 03; 100(3):540-543. PMID: 30675853; PMCID: PMC6402910.
      Citations: 8     Fields:    Translation:HumansCells
    77. Kay A, Garcia-Prats AJ, Mandalakas AM. HIV-associated pediatric tuberculosis: prevention, diagnosis and treatment. Curr Opin HIV AIDS. 2018 11; 13(6):501-506. PMID: 30286040; PMCID: PMC11849721.
      Citations: 2     Fields:    Translation:HumansCells
    78. Cranmer LM, Draper HR, Mandalakas AM, Kim S, McSherry G, Krezinski E, Coetzee J, Mitchell C, Nachman S, van der Linde M, Cotton MF, Hesseling AC, IMPAACT P1041 Team. High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial. Pediatr Infect Dis J. 2018 10; 37(10):e254-e256. PMID: 29462104; PMCID: PMC6095832.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    79. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. J Immunol. 2018 07 01; 201(1):124-133. PMID: 29752313; PMCID: PMC6008220.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    80. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 08; 99(2):310-316. PMID: 29692304; PMCID: PMC6090360.
      Citations: 10     Fields:    Translation:HumansCells
    81. Mandalakas AM, Highsmith HY, Harris NM, Pawlicka A, Kirchner HL. T-SPOT.TB Performance in Routine Pediatric Practice in a Low TB Burden Setting. Pediatr Infect Dis J. 2018 04; 37(4):292-297. PMID: 29140933.
      Citations: 3     Fields:    Translation:Humans
    82. Brunetti M, Rajasekharan S, Ustero P, Ngo K, Sikhondze W, Mzileni B, Mandalakas A, Kay AW. Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland. Glob Health Res Policy. 2018; 3:3. PMID: 29445773; PMCID: PMC5798177.
      Citations: 1     Fields:    
    83. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 11 07; 17(1):713. PMID: 29115944; PMCID: PMC5674833.
      Citations:    Fields:    
    84. Said K, Hella J, Knopp S, Nassoro T, Shija N, Aziz F, Mhimbira F, Schindler C, Mwingira U, Mandalakas AM, Manji K, Tanner M, Fenner L, Utzinger J. Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania. PLoS Negl Trop Dis. 2017 Nov; 11(11):e0006017. PMID: 29108003; PMCID: PMC5697890.
      Citations: 8     Fields:    Translation:HumansAnimals
    85. Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017 08 29; 17(1):593. PMID: 28851285; PMCID: PMC5576070.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    86. Mandalakas AM, Cobelens F. Tuberculosis-making predictions, especially about the future. Lancet Infect Dis. 2017 11; 17(11):1106-1107. PMID: 28827143; PMCID: PMC11851334.
      Citations:    Fields:    Translation:Humans
    87. Szkwarko D, Hirsch-Moverman Y, Du Plessis L, Du Preez K, Carr C, Mandalakas AM. Child contact management in high tuberculosis burden countries: A mixed-methods systematic review. PLoS One. 2017; 12(8):e0182185. PMID: 28763500; PMCID: PMC5538653.
      Citations: 41     Fields:    Translation:HumansPHPublic Health
    88. Ustero PA, Kay AW, Ngo K, Golin R, Tsabedze B, Mzileni B, Glickman J, Wisile Xaba M, Mavimbela G, Mandalakas AM. School and household tuberculosis contact investigations in Swaziland: Active TB case finding in a high HIV/TB burden setting. PLoS One. 2017; 12(6):e0178873. PMID: 28582435; PMCID: PMC5459449.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    89. Blevins Peratikos M, Kipp AM, Lindegren ML, Du QT, Renner L, Reubenson G, Ssali J, Yotebieng M, Mandalakas AM, Davies MA, Ballif M, Fenner L, Pettit AC, International Epidemiology Databases to Evaluate AIDS (IeDEA) Network, Carlucci JG. Tuberculosis Treatment Outcomes Among HIV/TB-Coinfected Children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) Network. J Acquir Immune Defic Syndr. 2017 Jun 01; 75(2):156-163. PMID: 28234689; PMCID: PMC5429189.
      Citations: 13     Fields:    Translation:Humans
    90. Bacha JM, Ngo K, Clowes P, Draper HR, Ntinginya EN, DiNardo A, Mangu C, Sabi I, Mtafya B, Mandalakas AM. Why being an expert - despite xpert -remains crucial for children in high TB burden settings. BMC Infect Dis. 2017 02 06; 17(1):123. PMID: 28166728; PMCID: PMC5294844.
      Citations: 12     Fields:    Translation:HumansCells
    91. van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC, Van der Zalm MM. Re: "It May Be Too Early to Try to Prove the Effect of Deworming on Tuberculin Reactivity". Pediatr Infect Dis J. 2017 02; 36(2):241-242. PMID: 28079838; PMCID: PMC11863664.
      Citations:    Fields:    Translation:Humans
    92. Mandalakas AM, Ngo K, Alonso Ustero P, Golin R, Anabwani F, Mzileni B, Sikhondze W, Stevens R. BUTIMBA: Intensifying the Hunt for Child TB in Swaziland through Household Contact Tracing. PLoS One. 2017; 12(1):e0169769. PMID: 28107473; PMCID: PMC5249050.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    93. DiNardo AR, Detjen A, Ustero P, Ngo K, Bacha J, Mandalakas AM. Culture is an imperfect and heterogeneous reference standard in pediatric tuberculosis. Tuberculosis (Edinb). 2016 12; 101S:S105-S108. PMID: 27727131.
      Citations: 14     Fields:    Translation:HumansCells
    94. Fox GJ, Schaaf HS, Mandalakas A, Chiappini E, Zumla A, Marais BJ. Preventing the spread of multidrug-resistant tuberculosis and protecting contacts of infectious cases. Clin Microbiol Infect. 2017 Mar; 23(3):147-153. PMID: 27592087; PMCID: PMC11849722.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    95. van Soelen N, Mandalakas AM, Jacobsen M, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, Hesseling AC, Van der Zalm MM. The Effect of Deworming on Tests of Tuberculosis Infection in Children With Recent Tuberculosis Exposure: A Randomized Controlled Trial. Pediatr Infect Dis J. 2016 06; 35(6):622-7. PMID: 26933841.
      Citations: 8     Fields:    Translation:HumansAnimals
    96. DiNardo AR, Mace EM, Lesteberg K, Cirillo JD, Mandalakas AM, Graviss EA, Orange JS, Makedonas G. Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation. J Infect Dis. 2016 08 01; 214(3):479-88. PMID: 27389351; PMCID: PMC4936644.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    97. DiNardo AR, Mandalakas AM, Maphalala G, Mtetwa G, Mndzebele T, Ustero P, Hlatshwayo M, Mace EM, Orange JS, Makedonas G. HIV Progression Perturbs the Balance of the Cell-Mediated and Anti-Inflammatory Adaptive and Innate Mycobacterial Immune Response. Mediators Inflamm. 2016; 2016:1478340. PMID: 27006526; PMCID: PMC4781991.
      Citations: 3     Fields:    Translation:HumansCells
    98. DiNardo AR, Lange C, Mandalakas AM. Editorial Commentary: 1, 2, 3 (Years)?????and You're Out: The End of a 123-year Historic Era. Clin Infect Dis. 2016 May 01; 62(9):1089-91. PMID: 26839384.
      Citations: 1     Fields:    Translation:HumansCells
    99. Mandalakas AM, Denkinger CM, Sester M, Lange C, Kalsdorf B. Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence. Pathog Immun. 2016; 1(2):308-329. PMID: 28217762; PMCID: PMC5315027.
      Citations: 6     
    100. DiNardo AR, Hahn A, Leyden J, Stager C, Jo Baron E, Graviss EA, Mandalakas AM, Guy E. Use of string test and stool specimens to diagnose pulmonary tuberculosis. Int J Infect Dis. 2015 Dec; 41:50-52. PMID: 26523638; PMCID: PMC4780405.
      Citations: 6     Fields:    Translation:HumansCells
    101. Graham SM, Cuevas LE, Jean-Philippe P, Browning R, Detjen AK, Gnanashanmugam D, Hesseling AC, Kampmann B, Mandalakas A, Marais BJ, Schito M, Spiegel HM, Starke JR, Worrell C, Zar HJ, Casenghi M. Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update. Clin Infect Dis. 2015 Oct 15; 61Suppl 3:S179-87. PMID: 26409281; PMCID: PMC4583568.
      Citations: 85     Fields:    Translation:Humans
    102. Priya Dhar C, Elena Gonzalez B, Dragga T, Bothe D, Mandalakas AM. Testing International Adoptees for Tuberculosis. Pediatr Infect Dis J. 2015 Oct; 34(10):1138-9. PMID: 26367807.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    103. Mandalakas AM, Kirchner HL, Walzl G, Gie RP, Schaaf HS, Cotton MF, Grewal HM, Hesseling AC. Optimizing the detection of recent tuberculosis infection in children in a high tuberculosis-HIV burden setting. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):820-30. PMID: 25622087; PMCID: PMC4407483.
      Citations: 21     Fields:    Translation:HumansCellsPHPublic Health
    104. Wiseman CA, Mandalakas AM, Kirchner HL, Gie RP, Schaaf HS, Walters E, Hesseling AC. Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study. Int J Tuberc Lung Dis. 2015 Apr; 19(4):446-53. PMID: 25860001.
      Citations: 9     Fields:    Translation:Humans
    105. Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM. Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis. Lancet Respir Med. 2015 Jun; 3(6):451-61. PMID: 25812968; PMCID: PMC4756280.
      Citations: 112     Fields:    Translation:Humans
    106. Carlucci JG, Jin L, Sanders JE, Mohapi EQ, Mandalakas AM. Development of tuberculosis infection control guidelines in a pediatric HIV clinic in sub-Saharan Africa. Public Health Action. 2015 Mar 21; 5(1):2-5. PMID: 26400595; PMCID: PMC4525369.
      Citations: 1     
    107. Musuuza JS, Singer ME, Mandalakas AM, Katamba A. Key actors' perspectives on cost-effectiveness analysis in Uganda: a cross-sectional survey. BMC Health Serv Res. 2014 Nov 04; 14:539. PMID: 25363234; PMCID: PMC4232642.
      Citations: 3     Fields:    Translation:Humans
    108. Ballif M, Renner L, Claude Dusingize J, Ayaya S, Wools-Kaloustian K, Cortes CP, McGowan CC, Graber C, Mandalakas AM, Mofenson LM, Egger M, Kumara Wati KD, Nallusamy R, Reubenson G, Davies MA, Fenner L, International Epidemiologic Databases to Evaluate AIDS (IeDEA), International Epidemiologic Databases to Evaluate AIDS IeDEA, Leroy V. Tuberculosis in Pediatric Antiretroviral Therapy Programs in Low- and Middle-Income Countries: Diagnosis and Screening Practices. J Pediatric Infect Dis Soc. 2015 Mar; 4(1):30-8. PMID: 26407355; PMCID: PMC5654358.
      Citations: 9     Fields:    Translation:HumansCells
    109. van Soelen N, du Preez K, van Wyk SS, Mandalakas AM, Enarson DA, Reid AJ, Hesseling AC. Does an isoniazid prophylaxis register improve tuberculosis contact management in South African children? PLoS One. 2013; 8(12):e80803. PMID: 24339884; PMCID: PMC3858233.
      Citations: 12     Fields:    Translation:Humans
    110. Skinner D, Hesseling AC, Francis C, Mandalakas AM. It's hard work, but it's worth it: the task of keeping children adherent to isoniazid preventive therapy. Public Health Action. 2013 Sep 21; 3(3):191-8. PMID: 26393028; PMCID: PMC4463130.
      Citations: 13     
    111. Cruz AT, Ahmed A, Mandalakas AM, Starke JR. Treatment of Latent Tuberculosis Infection in Children. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):248-58. PMID: 26619479.
      Citations: 6     Fields:    
    112. Chegou NN, Detjen AK, Thiart L, Walters E, Mandalakas AM, Hesseling AC, Walzl G. Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting. PLoS One. 2013; 8(5):e64226. PMID: 23691173; PMCID: PMC3655018.
      Citations: 29     Fields:    Translation:Humans
    113. Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC. Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction. Pediatr Infect Dis J. 2013 Mar; 32(3):e111-8. PMID: 23190784; PMCID: PMC11849719.
      Citations: 18     Fields:    Translation:HumansCells
    114. Skinner D, Mandalakas AM. Pasting together the preventive therapy puzzle. Int J Tuberc Lung Dis. 2013 Feb; 17(2):175-7. PMID: 23211672.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    115. Mandalakas AM, Starke JR, Cruz AT. Childhood tuberculosis: a preventable disease not being prevented. Pediatrics. 2012 Dec; 130(6):e1672-3. PMID: 23184112; PMCID: PMC11444303.
      Citations: 1     Fields:    Translation:Humans
    116. van Soelen N, Mandalakas AM, Kirchner HL, Walzl G, Grewal HM, Jacobsen M, Hesseling AC. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study. BMC Infect Dis. 2012 Sep 11; 12:211. PMID: 22966931; PMCID: PMC3482567.
      Citations: 12     Fields:    Translation:HumansAnimals
    117. Mandalakas AM, Hesseling AC, Gie RP, Schaaf HS, Marais BJ, Sinanovic E. Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting. Thorax. 2013 Mar; 68(3):247-55. PMID: 22717944.
      Citations: 31     Fields:    Translation:Humans
    118. Mandalakas AM, Kirchner HL, Lombard C, Walzl G, Grewal HM, Gie RP, Hesseling AC. Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection. Int J Tuberc Lung Dis. 2012 Aug; 16(8):1033-9. PMID: 22692027.
      Citations: 44     Fields:    Translation:HumansCellsPHPublic Health
    119. Cuevas LE, Browning R, Bossuyt P, Casenghi M, Cotton MF, Cruz AT, Dodd LE, Drobniewski F, Gale M, Graham SM, Grzemska M, Heinrich N, Hesseling AC, Huebner R, Jean-Philippe P, Kabra SK, Kampmann B, Lewinsohn D, Li M, Lienhardt C, Mandalakas AM, Marais BJ, Menzies HJ, Montepiedra G, Mwansambo C, Oberhelman R, Palumbo P, Russek-Cohen E, Shapiro DE, Smith B, Soto-Castellares G, Starke JR, Swaminathan S, Wingfield C, Worrell C. Evaluation of tuberculosis diagnostics in children: 2. Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis in children. Consensus from an expert panel. J Infect Dis. 2012 May 15; 205 Suppl 2:S209-15. PMID: 22476719; PMCID: PMC3334504.
      Citations: 45     Fields:    Translation:Humans
    120. Van Wyk SS, Mandalakas AM, Enarson DA, Gie RP, Beyers N, Hesseling AC. Tuberculosis contact investigation in a high-burden setting: house or household? Int J Tuberc Lung Dis. 2012 Feb; 16(2):157-62. PMID: 22236914.
      Citations: 14     Fields:    Translation:HumansPHPublic Health
    121. Hesseling AC, Mandalakas AM. Interferon-gamma release assays for childhood tuberculosis: what does the future hold? Int J Tuberc Lung Dis. 2011 Nov; 15(11):1423-4. PMID: 22008752.
      Citations:    Fields:    Translation:HumansCells
    122. du Preez K, Mandalakas AM, Kirchner HL, Grewal HM, Schaaf HS, van Wyk SS, Hesseling AC. Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children. Int J Tuberc Lung Dis. 2011 Nov; 15(11):1490-6, i. PMID: 22008762.
      Citations: 19     Fields:    Translation:HumansCellsPHPublic Health
    123. Mandalakas AM, Detjen AK, Hesseling AC. Can we accurately diagnose tuberculosis infection in children? Pediatr Infect Dis J. 2011 Sep; 30(9):817-8. PMID: 21849864.
      Citations: 5     Fields:    Translation:HumansCells
    124. Mandalakas AM, Detjen AK, Hesseling AC, Benedetti A, Menzies D. Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis. Int J Tuberc Lung Dis. 2011 Aug; 15(8):1018-32. PMID: 21669030.
      Citations: 76     Fields:    Translation:HumansCells
    125. van Wyk SS, Reid AJ, Mandalakas AM, Enarson DA, Beyers N, Morrison J, Hesseling AC. Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective. BMC Public Health. 2011 Jul 08; 11:544. PMID: 21740580; PMCID: PMC3150266.
      Citations: 28     Fields:    Translation:Humans
    126. Duncan B, Mandalakas A, Staton D, Anders B, Kurbasic M, Nakakeeto M, Mustafa G, Reyes A, Evangelista D. Child healthcare workers in resource-limited areas improve health with innovative low-cost projects. J Trop Pediatr. 2012 Apr; 58(2):120-4. PMID: 21652575.
      Citations:    Fields:    Translation:HumansPHPublic Health
    127. Mandalakas AM, Menzies D. Is screening immigrants for latent tuberculosis cost-effective? Lancet Infect Dis. 2011 Jun; 11(6):418-9. PMID: 21616450.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    128. George SA, Ko CA, Kirchner HL, Starke JR, Dragga TA, Mandalakas AM. The role of chest radiographs and tuberculin skin tests in tuberculosis screening of internationally adopted children. Pediatr Infect Dis J. 2011 May; 30(5):387-91. PMID: 21076362.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    129. Park H, Bothe D, Holsinger E, Kirchner HL, Olness K, Mandalakas A. The impact of nutritional status and longitudinal recovery of motor and cognitive milestones in internationally adopted children. Int J Environ Res Public Health. 2011 01; 8(1):105-16. PMID: 21318018; PMCID: PMC3037064.
      Citations: 6     Fields:    Translation:Humans
    130. Du Preez K, Hesseling AC, Mandalakas AM, Marais BJ, Schaaf HS. Opportunities for chemoprophylaxis in children with culture-confirmed tuberculosis. Ann Trop Paediatr. 2011; 31(4):301-10. PMID: 22041464.
      Citations: 13     Fields:    Translation:Humans
    131. Hesseling AC, Marais BJ, Kirchner HL, Mandalakas AM, Brittle W, Victor TC, Warren RM, Schaaf HS. Mycobacterial genotype is associated with disease phenotype in children. Int J Tuberc Lung Dis. 2010 Oct; 14(10):1252-8. PMID: 20843415.
      Citations: 14     Fields:    Translation:HumansCells
    132. Van Wyk SS, Hamade H, Hesseling AC, Beyers N, Enarson DA, Mandalakas AM. Recording isoniazid preventive therapy delivery to children: operational challenges. Int J Tuberc Lung Dis. 2010 May; 14(5):650-3. PMID: 20392361.
      Citations: 24     Fields:    Translation:Humans
    133. Yeo KT, Zhu X, Kirchner HL, LaBeaud AD, Mandalakas A. Candida skin testing is a poor adjunct to tuberculin skin testing in international adoptees. Pediatr Infect Dis J. 2009 Nov; 28(11):1020-1. PMID: 19820428; PMCID: PMC3133951.
      Citations:    Fields:    Translation:Humans
    134. Verla-Tebit E, Zhu X, Holsinger E, Mandalakas AM. Predictive value of immunization records and risk factors for immunization failure in internationally adopted children. Arch Pediatr Adolesc Med. 2009 May; 163(5):473-9. PMID: 19414695.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    135. Hesseling AC, Gie RP, Mandalakas AM. The predictive value of the ELISpot-based interferon-gamma-release assay for tuberculosis disease. Ann Intern Med. 2009 Mar 17; 150(6):428-9; author reply 429-30. PMID: 19293083.
      Citations:    Fields:    Translation:HumansCells
    136. Mandalakas AM, Chandawarkar A, Holsinger E. Global child health fellowship programs in demand. Pediatrics. 2008 Dec; 122(6):1417-8; author reply 1418. PMID: 19047273.
      Citations: 1     Fields:    Translation:Humans
    137. Mandalakas AM, Kirchner HL, Zhu X, Yeo KT, Starke JR. Interpretation of repeat tuberculin skin testing in international adoptees: conversions or boosting. Pediatr Infect Dis J. 2008 Oct; 27(10):913-9. PMID: 18776820.
      Citations: 6     Fields:    Translation:HumansCells
    138. Hesseling AC, Mandalakas AM, Kirchner HL, Chegou NN, Marais BJ, Stanley K, Zhu X, Black G, Beyers N, Walzl G. Highly discordant T cell responses in individuals with recent exposure to household tuberculosis. Thorax. 2009 Oct; 64(10):840-6. PMID: 18682523.
      Citations: 30     Fields:    Translation:HumansCells
    139. LaBeaud AD, Gorman AM, Koonce J, Kippes C, McLeod J, Lynch J, Gallagher T, King CH, Mandalakas AM. Rapid GIS-based profiling of West Nile virus transmission: defining environmental factors associated with an urban-suburban outbreak in Northeast Ohio, USA. Geospat Health. 2008 May; 2(2):215-25. PMID: 18686270; PMCID: PMC3140769.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    140. Mandalakas AM, Hesseling AC, Chegou NN, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N, Walzl G. High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis. 2008 Apr; 12(4):417-23. PMID: 18371268.
      Citations: 40     Fields:    Translation:HumansCells
    141. Mandalakas AM, Kirchner HL, Iverson S, Chesney M, Spencer MJ, Sidler A, Johnson D. Predictors of Mycobacterium tuberculosis infection in international adoptees. Pediatrics. 2007 Sep; 120(3):e610-6. PMID: 17766501.
      Citations: 3     Fields:    Translation:HumansCells
    142. Kile JR, Kippes C, King CH, Mandalakas AM, LaBeaud AD. Exposure to West Nile virus during the 2002 epidemic in Cuyahoga County, Ohio: a comparison of pediatric and adult behaviors. Public Health Rep. 2007 May-Jun; 122(3):356-61. PMID: 17518307; PMCID: PMC1847498.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    143. LaBeaud AD, Lisgaris MV, King CH, Mandalakas AM. Pediatric West Nile virus infection: neurologic disease presentations during the 2002 epidemic in Cuyahoga County, Ohio. Pediatr Infect Dis J. 2006 Aug; 25(8):751-3. PMID: 16874181.
      Citations: 6     Fields:    Translation:Humans
    144. Mandalakas AM, Kippes C, Sedransk J, Kile JR, Garg A, McLeod J, Berry RL, Marfin AA. West Nile virus epidemic, northeast Ohio, 2002. Emerg Infect Dis. 2005 Nov; 11(11):1774-7. PMID: 16318737; PMCID: PMC3367333.
      Citations: 19     Fields:    Translation:HumansCellsPHPublic Health
    145. Mandalakas AM, Starke JR. Current concepts of childhood tuberculosis. Semin Pediatr Infect Dis. 2005 Apr; 16(2):93-104. PMID: 15825140.
      Citations: 27     Fields:    Translation:HumansCellsPHPublic Health
    146. Mandalakas AM, Starke JR. Tuberculosis screening in immigrant children. Pediatr Infect Dis J. 2004 Jan; 23(1):71-2. PMID: 14743051.
      Citations:    Fields:    Translation:HumansPHPublic Health
    147. Torjesen K, Mandalakas A, Kahn R, Duncan B. International child health electives for pediatric residents. Arch Pediatr Adolesc Med. 1999 Dec; 153(12):1297-302. PMID: 10591310.
      Citations: 24     Fields:    Translation:Humans
    148. Mandalakas AM, Guay L, Musoke P, Carroll-Pankhurst C, Olness KN. Human immunodeficiency virus status and delayed-type hypersensitivity skin testing in Ugandan children. Pediatrics. 1999 Feb; 103(2):E21. PMID: 9925867.
      Citations: 2     Fields:    Translation:HumansCells
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