"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.
| Descriptor ID |
D038203
|
| MeSH Number(s) |
D12.776.306.366.100.300 D12.776.580.157.300
|
| Concept/Terms |
alpha-Crystallin B Chain- alpha-Crystallin B Chain
- B Chain, alpha-Crystallin
- alpha Crystallin B Chain
- Rosenthal Fiber Component
- alpha-Crystallin, B Subunit
- B Subunit alpha-Crystallin
- alpha Crystallin, B Subunit
- alpha B-Crystallin
- alpha B Crystallin
- Crystallins, alpha B Chain
|
Below are MeSH descriptors whose meaning is more general than "alpha-Crystallin B Chain".
Below are MeSH descriptors whose meaning is more specific than "alpha-Crystallin B Chain".
This graph shows the total number of publications written about "alpha-Crystallin B Chain" by people in this website by year, and whether "alpha-Crystallin B Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
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Below are the most recent publications written about "alpha-Crystallin B Chain" by people in Profiles.
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Desmin and aB-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. J Cell Sci. 2016 10 15; 129(20):3705-3720.
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aB-crystallin interacts with and prevents stress-activated proteolysis of focal adhesion kinase by calpain in cardiomyocytes. Nat Commun. 2014 Oct 16; 5:5159.
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Alpha-B-crystallin expression in human laryngeal squamous cell carcinoma tissues. Head Neck. 2015 Sep; 37(9):1344-8.
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What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator. Cell Cycle. 2008 Sep 15; 7(18):2833-9.
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Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):10703-8.
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Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation. Hum Mol Genet. 2005 Aug 15; 14(16):2335-47.
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Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature. Hum Mol Genet. 2003 Nov 01; 12(21):2753-64.