"Tolbutamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
| Descriptor ID |
D014044
|
| MeSH Number(s) |
D02.886.590.795.896 D02.948.828.896
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tolbutamide".
Below are MeSH descriptors whose meaning is more specific than "Tolbutamide".
This graph shows the total number of publications written about "Tolbutamide" by people in this website by year, and whether "Tolbutamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tolbutamide" by people in Profiles.
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Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels. J Neurochem. 2010 Apr; 113(2):530-42.
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Blockade of presynaptic K ATP channels reduces the zinc-mediated posttetanic depression at hippocampal mossy fiber synapses. Brain Res. 2010 Mar 12; 1320:22-7.
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Alterations in calcium channel currents underlie defective insulin secretion in a transgenic mouse. J Biol Chem. 1996 Jun 28; 271(26):15478-85.
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Defective glycolysis and calcium signaling underlie impaired insulin secretion in a transgenic mouse. J Biol Chem. 1995 Dec 01; 270(48):28688-95.
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The effect of tolbutamide and hepatic extraction of insulin and glucagon and hepatic glucose output in anesthetized dogs. Endocrinology. 1981 Aug; 109(2):443-50.
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Inhibition of glucose-induced release of insulin by aldose reductase inhibitors. Proc Natl Acad Sci U S A. 1972 Jun; 69(6):1435-9.
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The use of insulin dynamics in the evaluation of streptozotocin therapy of malignant insulinomas. J Clin Endocrinol Metab. 1971 Sep; 33(3):530-6.