"Retinaldehyde" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
| Descriptor ID |
D012172
|
| MeSH Number(s) |
D02.047.850 D02.455.326.271.665.202.495.690 D02.455.426.392.368.367.379.249.700.690 D02.455.849.131.495.690 D23.767.261.700.690
|
| Concept/Terms |
Retinaldehyde- Retinaldehyde
- Vitamin A Aldehyde
- Aldehyde, Vitamin A
- Retinene
- Axerophthal
- Retinal
|
Below are MeSH descriptors whose meaning is more general than "Retinaldehyde".
Below are MeSH descriptors whose meaning is more specific than "Retinaldehyde".
This graph shows the total number of publications written about "Retinaldehyde" by people in this website by year, and whether "Retinaldehyde" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1999 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinaldehyde" by people in Profiles.
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Reversal of skin aging with topical retinoids. Plast Reconstr Surg. 2014 Apr; 133(4):481e-490e.
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Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation. PLoS Genet. 2013 Aug; 9(8):e1003731.
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Evidence from Chlamydomonas on the photoactivation of rhodopsins without isomerization of their chromophore. Chem Biol. 2011 Jun 24; 18(6):733-42.
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Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. Hum Mol Genet. 2005 Dec 15; 14(24):3865-75.
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Role of the 9-methyl group of retinal in cone visual pigments. Biochemistry. 2004 May 11; 43(18):5532-8.
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Studies on pyrylretinal analogues of bacteriorhodopsin. Photochem Photobiol. 1999 Dec; 70(6):949-56.
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Isomerization of all-trans-9- and 13-desmethylretinol by retinal pigment epithelial cells. Biochemistry. 1999 Oct 12; 38(41):13542-50.
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A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin. Biophys J. 1997 Dec; 73(6):3182-91.
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Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin. Science. 1997 Jan 17; 275(5298):381-4.
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Abnormal level of retinoic acid in prostate cancer tissues. J Clin Endocrinol Metab. 1996 Jun; 81(6):2186-91.