"Tretinoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
| Descriptor ID |
D014212
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.818.500 D02.455.426.392.368.367.379.249.700.860.500 D02.455.849.131.495.818.800 D23.767.261.700.780
|
| Concept/Terms |
Tretinoin- Tretinoin
- Retinoic Acid
- Acid, Retinoic
- Vitamin A Acid
- Acid, Vitamin A
- all-trans-Retinoic Acid
- Acid, all-trans-Retinoic
- all trans Retinoic Acid
- trans-Retinoic Acid
- Acid, trans-Retinoic
- trans Retinoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Tretinoin".
Below are MeSH descriptors whose meaning is more specific than "Tretinoin".
This graph shows the total number of publications written about "Tretinoin" by people in this website by year, and whether "Tretinoin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 2 | 1 | 3 |
| 2006 | 2 | 1 | 3 |
| 2008 | 1 | 3 | 4 |
| 2009 | 3 | 1 | 4 |
| 2010 | 2 | 4 | 6 |
| 2011 | 1 | 1 | 2 |
| 2012 | 3 | 2 | 5 |
| 2013 | 1 | 2 | 3 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 2 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Tretinoin" by people in Profiles.
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Targeting MDSC Differentiation Using ATRA: A Phase I/II Clinical Trial Combining Pembrolizumab and All-Trans Retinoic Acid for Metastatic Melanoma. Clin Cancer Res. 2023 04 03; 29(7):1209-1219.
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Novel Approach to Measure Transepithelial Electrical Resistance in Intestinal Cells. Methods Mol Biol. 2023; 2650:35-42.
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Retinoic Acid Receptor Activation Reduces Metastatic Prostate Cancer Bone Lesions by Blocking the Endothelial-to-Osteoblast Transition. Cancer Res. 2022 09 02; 82(17):3158-3171.
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[Acute promyelocytic leukemia complicated with central nervous system involvement successfully treated with all-trans retinoic acid via nasogastric tube]. Rinsho Ketsueki. 2022; 63(1):26-30.
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Retinoid Regulation of Ocular Surface Innate Inflammation. Int J Mol Sci. 2021 Jan 22; 22(3).
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Enhanced Generation of Induced Cardiomyocytes Using a Small-Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming. J Am Heart Assoc. 2020 06 16; 9(12):e015686.
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Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition?following kidney injury. Kidney Int. 2019 03; 95(3):526-539.
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Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol. 2018 09 25; 30(10):457-470.
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Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab. Int Immunopharmacol. 2018 Oct; 63:282-291.
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The Cell Type-Specific Expression of Lhcgr in Mouse Ovarian Cells: Evidence for a DNA-Demethylation-Dependent Mechanism. Endocrinology. 2018 05 01; 159(5):2062-2074.