"Sphingosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
| Descriptor ID |
D013110
|
| MeSH Number(s) |
D02.033.100.700 D02.033.455.843 D02.092.063.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sphingosine".
Below are MeSH descriptors whose meaning is more specific than "Sphingosine".
This graph shows the total number of publications written about "Sphingosine" by people in this website by year, and whether "Sphingosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sphingosine" by people in Profiles.
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Sphingolipid Expression During Corneal Wound Healing in a Sphingosine Kinase 1 Knockout Model. Cells. 2026 Apr 21; 15(8).
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Amelioration of Fibrosis via S1P Inhibition Is Regulated by Inactivation of TGF-? and SPL Pathways in the Human Cornea. Int J Mol Sci. 2024 Jun 14; 25(12).
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Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation. Cell Metab. 2023 05 02; 35(5):855-874.e5.
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Potentiation of Sphingolipids and TGF-? in the human corneal stroma reveals intricate signaling pathway crosstalks. Exp Eye Res. 2023 06; 231:109487.
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Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model. Cells. 2022 09 17; 11(18).
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Unravelling the interplay of sphingolipids and TGF-? signaling in the human corneal stroma. PLoS One. 2017; 12(8):e0182390.
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Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. Hum Mol Genet. 2017 04 01; 26(7):1305-1317.
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Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. J Lipid Res. 2017 04; 58(4):636-648.
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An observational comparison of natalizumab vs. fingolimod using JCV serology to determine therapy. Mult Scler. 2014 Sep; 20(10):1381-90.
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The protein phosphatase 2A regulatory subunit B55a is a modulator of signaling and microRNA expression in acute myeloid leukemia cells. Biochim Biophys Acta. 2014 Sep; 1843(9):1969-77.