"Codon, Initiator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.
| Descriptor ID |
D018387
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| MeSH Number(s) |
D13.444.735.544.355.225 G05.360.335.355.225 G05.360.340.024.340.137.190.225
|
| Concept/Terms |
Codon, Initiator- Codon, Initiator
- Codons, Initiator
- Initiator Codons
- Initiator Codon
- Start Codon
- Codon, Start
- Codons, Start
- Start Codons
- Codon, Initiation
- Codons, Initiation
- Initiation Codon
- Initiation Codons
|
Below are MeSH descriptors whose meaning is more general than "Codon, Initiator".
Below are MeSH descriptors whose meaning is more specific than "Codon, Initiator".
This graph shows the total number of publications written about "Codon, Initiator" by people in this website by year, and whether "Codon, Initiator" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Codon, Initiator" by people in Profiles.
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Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes Dev. 2019 07 01; 33(13-14):871-885.
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Non-AUG translation: a new start for protein synthesis in eukaryotes. Genes Dev. 2017 09 01; 31(17):1717-1731.
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Phenotypic variability of osteogenesis imperfecta type V caused by an IFITM5 mutation. J Bone Miner Res. 2013 Jul; 28(7):1523-30.
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SET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensation. J Biol Chem. 2011 Jun 17; 286(24):21393-400.
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Effect of point mutations in translation initiation context on the expression of recombinant human alpha(1)-proteinase inhibitor in transgenic tomato plants. Plant Cell Rep. 2009 Dec; 28(12):1791-8.
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The mitochondrial trn-cox1 locus: rapid evolution in Pompilidae and evidence of bias in cox1 initiation and termination codon usage. Mitochondrial DNA. 2009 Feb; 20(1):15-25.
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A small stem loop element directs internal initiation of the URE2 internal ribosome entry site in Saccharomyces cerevisiae. J Biol Chem. 2008 Jul 04; 283(27):19011-25.
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28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Res. 2007 Dec; 17(12):1797-808.
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Transcriptional switch of the dia1 and impA promoter during the growth/differentiation transition. Eukaryot Cell. 2005 Aug; 4(8):1477-82.
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Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue- and cell type-specific functions. Biochemistry. 2005 May 24; 44(20):7395-405.