"Lactosylceramides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycosphingolipids which contain as their polar head group a lactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in lactosylceramide beta-galactosidase, is the cause of lactosylceramidosis.
| Descriptor ID |
D007790
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| MeSH Number(s) |
D02.065.313.612 D09.400.410.420.525.200.612 D10.390.470.675.200.612 D10.570.877.360.612.200.612
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lactosylceramides".
Below are MeSH descriptors whose meaning is more specific than "Lactosylceramides".
This graph shows the total number of publications written about "Lactosylceramides" by people in this website by year, and whether "Lactosylceramides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactosylceramides" by people in Profiles.
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The lysosomal disease caused by mutant VPS33A. Hum Mol Genet. 2019 08 01; 28(15):2514-2530.
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Primary alveolar epithelial cell surface membrane microdomain function is required for Pneumocystis ?-glucan-induced inflammatory responses. Innate Immun. 2012 Oct; 18(5):709-16.
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Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy. 2011 Jun; 7(6):629-42.
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Lactosylceramide causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells. Med Sci Monit. 2009 Sep; 15(9):BR270-4.
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Lactosylceramide promotes cell migration and proliferation through activation of ERK1/2 in human aortic smooth muscle cells. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H400-8.
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Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms. Am J Respir Cell Mol Biol. 2005 Jun; 32(6):490-7.
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Pneumocystis carinii cell wall beta-glucan induces release of macrophage inflammatory protein-2 from alveolar epithelial cells via a lactosylceramide-mediated mechanism. J Biol Chem. 2003 Jan 17; 278(3):2043-50.
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Antibodies against ganglioside GT3 in the sera of patients with type I diabetes mellitus. J Immunol. 1989 Jun 01; 142(11):3826-32.
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Neutral glycolipid antigens as developmental markers of mouse teratocarcinoma and early embryos: an immunologic and chemical analysis. J Immunol. 1982 Aug; 129(2):603-9.
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An improved technique for separation of neutral glycosphingolipids by high-performance liquid chromatography. J Lipid Res. 1980 May; 21(4):473-7.