"Edar Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ectodysplasin receptor subtype that is specific for ECTODYSPLASIN A1. It signals via the specific signaling adaptor EDAR-ASSOCIATED DEATH DOMAIN PROTEIN. Loss of function of the edar receptor is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA and ECTODERMAL DYSPLASIA 3, ANHIDROTIC.
| Descriptor ID |
D053339
|
| MeSH Number(s) |
D12.776.543.750.690.550 D12.776.543.750.705.852.760.347.500
|
| Concept/Terms |
Edar Receptor- Edar Receptor
- Receptor, Edar
- Tumor Necrosis Factor Receptor Superfamily, Member EDAR
- Receptors, Edar
- Edar Receptors
- Ectodysplasin A1 Receptor
- Receptor, Ectodysplasin A1
- Ectodysplasin 1, Anhidrotic Receptor
|
Below are MeSH descriptors whose meaning is more general than "Edar Receptor".
Below are MeSH descriptors whose meaning is more specific than "Edar Receptor".
This graph shows the total number of publications written about "Edar Receptor" by people in this website by year, and whether "Edar Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Edar Receptor" by people in Profiles.
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Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis. Eur J Hum Genet. 2010 Jan; 18(1):19-25.
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Genome-wide detection and characterization of positive selection in human populations. Nature. 2007 Oct 18; 449(7164):913-8.
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Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9075-80.
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The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development. Dev Biol. 2004 Apr 01; 268(1):185-94.
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Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature. 2001 Dec 20-27; 414(6866):913-6.
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Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis. Development. 2000 Nov; 127(21):4691-700.
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Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet. 1999 Aug; 22(4):366-9.
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Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet. 1999 Aug; 22(4):370-4.