"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
| Descriptor ID |
D001973
|
| MeSH Number(s) |
D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
|
| Concept/Terms |
Bromodeoxyuridine- Bromodeoxyuridine
- Bromouracil Deoxyriboside
- Deoxyriboside, Bromouracil
- 5-Bromo-2'-deoxyuridine
- 5 Bromo 2' deoxyuridine
- BrdU
- BUdR
- 5-Bromodeoxyuridine
- 5 Bromodeoxyuridine
- Broxuridine
|
Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".
Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".
This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 9 | 9 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.
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Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia. Gastroenterology. 2020 02; 158(3):598-609.e5.
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Detecting Hematopoietic Stem Cell Proliferation Using BrdU Incorporation. Methods Mol Biol. 2018; 1686:91-103.
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Detection of DNA double-strand breaks by pulsed-field gel electrophoresis. Genes Cells. 2017 Jan; 22(1):84-93.
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Analyses of programmed cell death in dendritic cells. Methods Mol Biol. 2013; 979:51-63.
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Genome-wide analysis of replication timing in mammalian cells: troubleshooting problems encountered when comparing different cell types. Methods. 2012 Jun; 57(2):165-9.
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Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors. J Natl Cancer Inst. 2012 Feb 08; 104(3):189-210.
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ID4 regulates mammary gland development by suppressing p38MAPK activity. Development. 2011 Dec; 138(23):5247-56.
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Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. J Neurosci. 2011 Aug 31; 31(35):12413-25.
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Evaluation of the transforming growth factor-beta activity in normal and dry eye human tears by CCL-185 cell bioassay. Cornea. 2010 Sep; 29(9):1048-54.
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Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4436-41.