"Sulbactam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
| Descriptor ID |
D013407
|
| MeSH Number(s) |
D02.065.589.099.750.812 D02.886.108.750.812 D03.633.100.300.750.812
|
| Concept/Terms |
Sulbactam- Sulbactam
- Penicillanic Acid Sulfone
- Sulfone, Penicillanic Acid
|
Below are MeSH descriptors whose meaning is more general than "Sulbactam".
Below are MeSH descriptors whose meaning is more specific than "Sulbactam".
This graph shows the total number of publications written about "Sulbactam" by people in this website by year, and whether "Sulbactam" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sulbactam" by people in Profiles.
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Effectiveness of Outpatient Antibiotics After Surgical Drainage of Abscesses in Reducing Treatment Failure. J Emerg Med. 2018 10; 55(4):512-521.
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Beta-lactam antibiotic-induced pseudoporphyria. J Am Acad Dermatol. 2004 Aug; 51(2 Suppl):S80-2.
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Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases. Protein Eng. 2000 Apr; 13(4):267-74.
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Characterization of a PSE-4 mutant with different properties in relation to penicillanic acid sulfones: importance of residues 216 to 218 in class A beta-lactamases. Antimicrob Agents Chemother. 1998 Sep; 42(9):2319-25.
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Comparison of ampicillin/sulbactam plus aminoglycoside vs. ampicillin plus clindamycin plus aminoglycoside in the treatment of intraabdominal infections in children. The Multicenter Group. Pediatr Infect Dis J. 1998 Mar; 17(3 Suppl):S15-8; discussion S20-1.
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Survey of antibiotic susceptibility among gram-negative bacilli at a cancer center. Chemotherapy. 1996 Sep-Oct; 42(5):348-53.
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Imipenem or cefoperazone-sulbactam combined with vancomycin for therapy of presumed or proven infection in neutropenic cancer patients. Eur J Clin Microbiol Infect Dis. 1996 Aug; 15(8):625-34.
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Bacteriologic profile of surgical infection after antibiotic prophylaxis. Head Neck. 1993 Nov-Dec; 15(6):526-31.
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Nonwound infections following head and neck oncologic surgery. Laryngoscope. 1993 Jan; 103(1 Pt 1):22-7.
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Ampicillin-sulbactam vs clindamycin in head and neck oncologic surgery. The need for gram-negative coverage. Arch Otolaryngol Head Neck Surg. 1992 Nov; 118(11):1159-63.