"Glutamate-Ammonia Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.
| Descriptor ID |
D005974
|
| MeSH Number(s) |
D08.811.464.259.200.600
|
| Concept/Terms |
Glutamate-Ammonia Ligase- Glutamate-Ammonia Ligase
- Glutamate Ammonia Ligase
- Ligase, Glutamate-Ammonia
- Glutamate Ammonia Ligase (ADP)
- Glutamine Synthetase
- Synthetase, Glutamine
|
Below are MeSH descriptors whose meaning is more general than "Glutamate-Ammonia Ligase".
Below are MeSH descriptors whose meaning is more specific than "Glutamate-Ammonia Ligase".
This graph shows the total number of publications written about "Glutamate-Ammonia Ligase" by people in this website by year, and whether "Glutamate-Ammonia Ligase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutamate-Ammonia Ligase" by people in Profiles.
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Glutamine synthetase mediates sorafenib sensitivity in ?-catenin-active hepatocellular carcinoma cells. Exp Mol Med. 2018 01 05; 50(1):e421.
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Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metab. 2016 11 08; 24(5):685-700.
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Development of cholinergic amacrine cells is visual activity-dependent in the postnatal mouse retina. J Comp Neurol. 2005 Apr 11; 484(3):331-43.
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Corticosterone has independent effects on tissue maturation and growth in the suckling rat. Pediatr Res. 1996 Mar; 39(3):395-400.
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Hepatocyte heterogeneity in glutamate metabolism and bidirectional transport in perfused rat liver. Eur J Biochem. 1989 Oct 20; 185(1):189-95.
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Functional hepatocyte heterogeneity. Vascular 2-oxoglutarate is almost exclusively taken up by perivenous, glutamine-synthetase-containing hepatocytes. Eur J Biochem. 1989 May 15; 181(3):709-16.
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Steroid hormone regulation of specific gene expression. Vitam Horm. 1978; 36:259-95.
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Cell density-dependent stimulation of glutamine synthetase activity in cultured mouse teratoma cells. Exp Cell Res. 1975 Sep; 94(2):459-64.