"Glutamate-Ammonia Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.
Descriptor ID |
D005974
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MeSH Number(s) |
D08.811.464.259.200.600
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Concept/Terms |
Glutamate-Ammonia Ligase- Glutamate-Ammonia Ligase
- Glutamate Ammonia Ligase
- Ligase, Glutamate-Ammonia
- Glutamate Ammonia Ligase (ADP)
- Glutamine Synthetase
- Synthetase, Glutamine
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Below are MeSH descriptors whose meaning is more general than "Glutamate-Ammonia Ligase".
Below are MeSH descriptors whose meaning is more specific than "Glutamate-Ammonia Ligase".
This graph shows the total number of publications written about "Glutamate-Ammonia Ligase" by people in this website by year, and whether "Glutamate-Ammonia Ligase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1997 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutamate-Ammonia Ligase" by people in Profiles.
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Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish. Dis Model Mech. 2019 09 25; 12(9).
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Glutamine synthetase mediates sorafenib sensitivity in ?-catenin-active hepatocellular carcinoma cells. Exp Mol Med. 2018 01 05; 50(1):e421.
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Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation. Mol Vis. 2016; 22:1468-1489.
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Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. Cell Metab. 2016 11 08; 24(5):685-700.
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A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer. PLoS One. 2014; 9(2):e88667.
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The effect of portacaval anastomosis on the expression of glutamine synthetase and ornithine aminotransferase in perivenous hepatocytes. Can J Physiol Pharmacol. 2013 May; 91(5):362-8.
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Hepatic glutamate metabolism: a tale of 2 hepatocytes. Am J Clin Nutr. 2009 Sep; 90(3):857S-861S.
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Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met. Int J Cancer. 2009 Apr 15; 124(8):1767-72.
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Development of cholinergic amacrine cells is visual activity-dependent in the postnatal mouse retina. J Comp Neurol. 2005 Apr 11; 484(3):331-43.
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In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2699-704.