"Glucagon-Like Peptide 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 33-amino acid peptide derived from the C-terminal of PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. It stimulates intestinal mucosal growth and decreased apoptosis of ENTEROCYTES. GLP-2 enhances gastrointestinal function and plays an important role in nutrient homeostasis.
| Descriptor ID |
D053767
|
| MeSH Number(s) |
D06.472.317.469.500.750
|
| Concept/Terms |
Glucagon-Like Peptide 2- Glucagon-Like Peptide 2
- Glucagon Like Peptide 2
- Proglucagon (126-158)
- Glucagon-Like Peptide-2 (1-33)
|
Below are MeSH descriptors whose meaning is more general than "Glucagon-Like Peptide 2".
Below are MeSH descriptors whose meaning is more specific than "Glucagon-Like Peptide 2".
This graph shows the total number of publications written about "Glucagon-Like Peptide 2" by people in this website by year, and whether "Glucagon-Like Peptide 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 4 | 2 | 6 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glucagon-Like Peptide 2" by people in Profiles.
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Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model. Am J Physiol Gastrointest Liver Physiol. 2019 05 01; 316(5):G641-G652.
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Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo. J Nutr Biochem. 2017 02; 40:201-208.
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Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 01; 309(5):G310-23.
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Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. J Pediatr Gastroenterol Nutr. 2014 Jun; 58(6):694-702.
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Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs. J Nutr. 2013 Dec; 143(12):1899-905.
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Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.
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Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates. Am J Physiol Gastrointest Liver Physiol. 2013 Aug 15; 305(4):G277-85.
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GLP-2 delays but does not prevent the onset of necrotizing enterocolitis in preterm pigs. J Pediatr Gastroenterol Nutr. 2013 Jun; 56(6):623-30.
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Digestive physiology of the pig symposium: intestinal bile acid sensing is linked to key endocrine and metabolic signaling pathways. J Anim Sci. 2013 May; 91(5):1991-2000.
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Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). J Nutr. 2013 May; 143(5):563-70.