"Clavulanic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
| Descriptor ID |
D019818
|
| MeSH Number(s) |
D02.065.589.099.374.160 D03.633.100.300.374.160
|
| Concept/Terms |
Clavulanate Potassium- Clavulanate Potassium
- Potassium, Clavulanate
- Potassium Clavulanate
- Clavulanate, Potassium
- Clavulanic Acid, Monopotassium Salt
|
Below are MeSH descriptors whose meaning is more general than "Clavulanic Acid".
Below are MeSH descriptors whose meaning is more specific than "Clavulanic Acid".
This graph shows the total number of publications written about "Clavulanic Acid" by people in this website by year, and whether "Clavulanic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clavulanic Acid" by people in Profiles.
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Reconciling the Potentially Irreconcilable? Genotypic and Phenotypic Amoxicillin-Clavulanate Resistance in Escherichia coli. Antimicrob Agents Chemother. 2020 05 21; 64(6).
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Molecular epidemiology of ESBL-producing Klebsiella pneumoniae isolates in intensive care units of a tertiary care hospital, North of Iran. Cell Mol Biol (Noisy-le-grand). 2018 May 30; 64(7):75-79.
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A bullous lesion in a neutropenic adolescent. Pediatr Emerg Care. 2009 Feb; 25(2):100-1.
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Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):541-5.
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Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases. Protein Eng. 2000 Apr; 13(4):267-74.
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Antimicrobial update. Drug Intell Clin Pharm. 1986 Jul-Aug; 20(7-8):583-6.