"Clavulanic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
| Descriptor ID |
D019818
|
| MeSH Number(s) |
D02.065.589.099.374.160 D03.633.100.300.374.160
|
| Concept/Terms |
Clavulanate Potassium- Clavulanate Potassium
- Potassium, Clavulanate
- Potassium Clavulanate
- Clavulanate, Potassium
- Clavulanic Acid, Monopotassium Salt
|
Below are MeSH descriptors whose meaning is more general than "Clavulanic Acid".
Below are MeSH descriptors whose meaning is more specific than "Clavulanic Acid".
This graph shows the total number of publications written about "Clavulanic Acid" by people in this website by year, and whether "Clavulanic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clavulanic Acid" by people in Profiles.
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Clavulanate combinations with mecillinam, cefixime or cefpodoxime against ESBL-producing Enterobacterales frequently associated with blaOXA-1 in a paediatric population with febrile urinary tract infections. J Antimicrob Chemother. 2021 10 11; 76(11):2839-2846.
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Molecular epidemiology of ESBL-producing Klebsiella pneumoniae isolates in intensive care units of a tertiary care hospital, North of Iran. Cell Mol Biol (Noisy-le-grand). 2018 May 30; 64(7):75-79.
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In vitro interaction between cefixime and amoxicillin-clavulanate against extended-spectrum-beta-lactamase-producing Escherichia coli causing urinary tract infection. J Clin Microbiol. 2012 Jul; 50(7):2540-1.
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A bullous lesion in a neutropenic adolescent. Pediatr Emerg Care. 2009 Feb; 25(2):100-1.
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Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients. Support Care Cancer. 2004 Sep; 12(9):657-62.
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Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis. Biochem Biophys Res Commun. 2004 Jan 16; 313(3):541-5.
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Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases. Protein Eng. 2000 Apr; 13(4):267-74.
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Randomized comparison between antibiotics alone and antibiotics plus granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived in cancer patients with fever and neutropenia. Am J Med. 1996 Jan; 100(1):17-23.
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Beta-lactam regimens for the febrile neutropenic patient. Cancer. 1990 Jan 01; 65(1):9-16.
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Antimicrobial update. Drug Intell Clin Pharm. 1986 Jul-Aug; 20(7-8):583-6.