"Antibodies, Blocking" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
| Descriptor ID |
D019138
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| MeSH Number(s) |
D12.776.124.486.485.114.143 D12.776.124.790.651.114.143 D12.776.377.715.548.114.143
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Antibodies, Blocking".
Below are MeSH descriptors whose meaning is more specific than "Antibodies, Blocking".
This graph shows the total number of publications written about "Antibodies, Blocking" by people in this website by year, and whether "Antibodies, Blocking" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 2 | 2 |
| 2000 | 2 | 0 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 0 | 3 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 4 | 5 |
| 2010 | 2 | 6 | 8 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antibodies, Blocking" by people in Profiles.
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COVID-19 booster vaccination during pregnancy enhances maternal binding and neutralizing antibody responses and transplacental antibody transfer to the newborn. Vaccine. 2023 08 14; 41(36):5296-5303.
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Comparison of Microneutralization and Histo-Blood Group Antigen-Blocking Assays for Functional Norovirus Antibody Detection. J Infect Dis. 2020 02 18; 221(5):739-743.
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Peanut oral immunotherapy induces blocking antibodies but does not change the functional characteristics of peanut-specific IgE. J Allergy Clin Immunol. 2020 01; 145(1):440-443.e5.
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Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018 05; 557(7706):570-574.
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Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades. J Virol. 2017 07 15; 91(14).
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The influence of tumor necrosis factor-a on the tumorigenic Wnt-signaling pathway in human mammary tissue from obese women. Oncotarget. 2017 May 30; 8(22):36127-36136.
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Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells. J Biol Chem. 2017 06 16; 292(24):10295-10305.
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Antibody responses to botulinum neurotoxin type A of toxin-treated spastic equinus children with cerebral palsy: A randomized clinical trial comparing two injection schedules. J Neuroimmunol. 2017 05 15; 306:31-39.
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IL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosis. Mucosal Immunol. 2017 07; 10(4):1031-1042.
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Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):E5830-E5837.