"Apoprotein(a)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
| Descriptor ID |
D053241
|
| MeSH Number(s) |
D10.532.350.500 D12.776.521.400.500
|
| Concept/Terms |
Apoprotein(a)- Apoprotein(a)
- Apo Lp(a)
- Apolipoprotein (a)
- Apoprotein (a)
- Apolipoprotein Lp(a+)
- Apolipoprotein(a)
- Antiangiogenic AK38 Protein
- Protein, Antiangiogenic AK38
- Apolipoprotein Lp(a)
|
Below are MeSH descriptors whose meaning is more general than "Apoprotein(a)".
Below are MeSH descriptors whose meaning is more specific than "Apoprotein(a)".
This graph shows the total number of publications written about "Apoprotein(a)" by people in this website by year, and whether "Apoprotein(a)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apoprotein(a)" by people in Profiles.
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High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner. Atherosclerosis. 2023 11; 384:117150.
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A point mutation in the photosystem I P700 chlorophyll a apoprotein A1 gene confers variegation in Helianthus annuus L. Plant Mol Biol. 2020 Jul; 103(4-5):373-389.
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Interaction of apolipoprotein[a] with apolipoproteinB-100 Cys3734 region in lipoprotein[a] is confirmed immunochemically. J Protein Chem. 1996 Jan; 15(1):17-25.
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Electrophoretic methods for quantitation of lipoprotein [a]. Methods Enzymol. 1996; 263:218-37.
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Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus. J Clin Invest. 1994 Jun; 93(6):2526-34.
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Interaction of LDL and Lp[a] with human skin fibroblasts. Chem Phys Lipids. 1994 Jan; 67-68:145-52.
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Identification and quantification of apolipoproteins in addition to apo[a] and apo B-100 in human lipoprotein[a]. Chem Phys Lipids. 1994 Jan; 67-68:35-42.
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Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. J Clin Invest. 1991 Jun; 87(6):2153-61.
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Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med. 1990 May 24; 322(21):1494-9.
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Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation. Arteriosclerosis. 1989 Sep-Oct; 9(5):593-603.