"Pinacidil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
| Descriptor ID |
D020110
|
| MeSH Number(s) |
D02.078.370.729
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pinacidil".
Below are MeSH descriptors whose meaning is more specific than "Pinacidil".
This graph shows the total number of publications written about "Pinacidil" by people in this website by year, and whether "Pinacidil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pinacidil" by people in Profiles.
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Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain. Brain Res. 2014 Mar 20; 1554:29-35.
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Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. Gastroenterology. 2009 Aug; 137(2):569-78, 578.e1.
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Recombinant cardiac ATP-sensitive K+ channel subunits confer resistance to chemical hypoxia-reoxygenation injury. Circulation. 1998 Oct 13; 98(15):1548-55.
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Relaxation by calcitonin gene-related peptide may involve activation of K+ channels in the human uterine artery. Eur J Pharmacol. 1993 Oct 05; 242(3):255-61.