"3-Iodobenzylguanidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
| Descriptor ID |
D019797
|
| MeSH Number(s) |
D02.078.370.510 D02.455.426.559.389.454.300 D02.455.526.581.496.300
|
| Concept/Terms |
3-Iodobenzylguanidine- 3-Iodobenzylguanidine
- 3 Iodobenzylguanidine
- MIBG
- meta-Iodobenzylguanidine
- meta Iodobenzylguanidine
- Iobenguane
- m-Iodobenzylguanidine
- m Iodobenzylguanidine
|
Below are MeSH descriptors whose meaning is more general than "3-Iodobenzylguanidine".
Below are MeSH descriptors whose meaning is more specific than "3-Iodobenzylguanidine".
This graph shows the total number of publications written about "3-Iodobenzylguanidine" by people in this website by year, and whether "3-Iodobenzylguanidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "3-Iodobenzylguanidine" by people in Profiles.
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Time to resolution of iodine-123 metaiodobenzylguanidine (123 I-MIBG) avidity and local control outcomes for high-risk neuroblastoma following radiation therapy. J Med Imaging Radiat Oncol. 2023 Feb; 67(1):81-88.
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Revisions to the International Neuroblastoma Response Criteria: A Consensus Statement From the National Cancer Institute Clinical Trials Planning Meeting. J Clin Oncol. 2017 Aug 01; 35(22):2580-2587.
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Incidence and risk factors for secondary malignancy in patients with neuroblastoma after treatment with (131)I-metaiodobenzylguanidine. Eur J Cancer. 2016 10; 66:144-52.
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Radiation therapy to the primary and postinduction chemotherapy MIBG-avid sites in high-risk neuroblastoma. Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4):858-62.
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Changing paradigms in the treatment of malignant pheochromocytoma. Cancer Control. 2011 Apr; 18(2):104-12.
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Myocardial sympathetic innervation and long-term left ventricular mechanical unloading. JACC Cardiovasc Imaging. 2010 Jan; 3(1):64-70.
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Sympathetic denervation and reinnervation after the maze procedure. J Nucl Med. 2005 Jul; 46(7):1089-94.
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Biodistribution of post-therapeutic versus diagnostic (131)I-MIBG scans in children with neuroblastoma. Pediatr Blood Cancer. 2004 Mar; 42(3):268-74.
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Is preoperative iodine 123 meta-iodobenzylguanidine scintigraphy routinely necessary before initial adrenalectomy for pheochromocytoma? Surgery. 2003 Dec; 134(6):918-22; discussion 922-3.
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Targeted radiotherapy with submyeloablative doses of 131I-MIBG is effective for disease palliation in highly refractory neuroblastoma. J Pediatr Hematol Oncol. 2003 Oct; 25(10):769-73.