"Alu Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
| Descriptor ID |
D020087
|
| MeSH Number(s) |
G02.111.570.080.708.330.800.800.050 G05.360.080.708.330.800.800.050 G05.360.340.024.425.800.800.050
|
| Concept/Terms |
Alu Elements- Alu Elements
- Alu Element
- Element, Alu
- Elements, Alu
- Alu Family
- Alu Families
- Families, Alu
- Family, Alu
- Alu Repetitive Sequences
- Alu Repetitive Sequence
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
|
Below are MeSH descriptors whose meaning is more general than "Alu Elements".
Below are MeSH descriptors whose meaning is more specific than "Alu Elements".
This graph shows the total number of publications written about "Alu Elements" by people in this website by year, and whether "Alu Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 4 | 5 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 4 | 6 |
| 2009 | 0 | 6 | 6 |
| 2010 | 4 | 0 | 4 |
| 2011 | 4 | 0 | 4 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 5 | 6 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alu Elements" by people in Profiles.
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hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing. Mol Cell. 2024 Jun 06; 84(11):2087-2103.e8.
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ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses. J Exp Med. 2021 09 06; 218(9).
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A novel homozygous SLC13A5 whole-gene deletion generated by Alu/Alu-mediated rearrangement in an Iraqi family with epileptic encephalopathy. Am J Med Genet A. 2021 07; 185(7):1972-1980.
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Regulation of RNA editing by RNA-binding proteins in human cells. Commun Biol. 2019; 2:19.
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Alu insertion variants alter mRNA splicing. Nucleic Acids Res. 2019 01 10; 47(1):421-431.
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LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV. Hum Mutat. 2018 12; 39(12):1916-1925.
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Predicting human genes susceptible to genomic instability associated with Alu/Alu-mediated rearrangements. Genome Res. 2018 08; 28(8):1228-1242.
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Alu Insertion Polymorphisms as Evidence for Population Structure in Baboons. Genome Biol Evol. 2017 09 01; 9(9):2418-2427.
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De novo methylation in male germ cells of the common marmoset monkey occurs during postnatal development and is maintained in vitro. Epigenetics. 2017 07 03; 12(7):527-539.
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Mechanisms for the Generation of Two Quadruplications Associated with Split-Hand Malformation. Hum Mutat. 2016 Feb; 37(2):160-4.