"Phenanthrenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
POLYCYCLIC AROMATIC HYDROCARBONS composed of three fused BENZENE rings.
Descriptor ID |
D010616
|
MeSH Number(s) |
D02.455.426.559.847.723 D04.615.723
|
Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phenanthrenes".
Below are MeSH descriptors whose meaning is more specific than "Phenanthrenes".
This graph shows the total number of publications written about "Phenanthrenes" by people in this website by year, and whether "Phenanthrenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 1 | 1 | 2 |
2008 | 2 | 1 | 3 |
2009 | 3 | 0 | 3 |
2010 | 3 | 0 | 3 |
2011 | 3 | 1 | 4 |
2014 | 2 | 0 | 2 |
2018 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenanthrenes" by people in Profiles.
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Combining triptolide with ABT-199 is effective against acute myeloid leukemia through reciprocal regulation of Bcl-2 family proteins and activation of the intrinsic apoptotic pathway. Cell Death Dis. 2020 07 22; 11(7):555.
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Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial. JAMA. 2018 09 04; 320(9):880-891.
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GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer. Oncogene. 2015 Jun 04; 34(23):2958-67.
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Preclinical antileukemic activity, toxicology, toxicokinetics and formulation development of triptolide derivative MRx102. Cancer Chemother Pharmacol. 2014 May; 73(5):961-74.
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Activation of apoptosis signaling eliminates CD34+ progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors. Leukemia. 2012 Apr; 26(4):788-94.
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MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML. Leukemia. 2012 Mar; 26(3):443-50.
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PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1. Biochem Biophys Res Commun. 2011 Aug 26; 412(2):379-84.
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Knockout of hepatic P450 reductase aggravates triptolide-induced toxicity. Toxicol Lett. 2011 Aug 10; 205(1):47-54.
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DNA-dependent protein kinase and ataxia telangiectasia mutated (ATM) promote cell survival in response to NK314, a topoisomerase IIa inhibitor. Mol Pharmacol. 2011 Aug; 80(2):321-7.
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Role of Hsp-70 in triptolide-mediated cell death of neuroblastoma. J Surg Res. 2010 Sep; 163(1):72-8.