"Aristolochic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).
| Descriptor ID |
D034341
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| MeSH Number(s) |
D02.455.426.559.847.723.089 D02.640.139 D04.615.723.089
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aristolochic Acids".
Below are MeSH descriptors whose meaning is more specific than "Aristolochic Acids".
This graph shows the total number of publications written about "Aristolochic Acids" by people in this website by year, and whether "Aristolochic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aristolochic Acids" by people in Profiles.
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Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC). World J Urol. 2017 Mar; 35(3):379-387.
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Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity. Toxicol Sci. 2011 Aug; 122(2):288-96.