Guanylyl Imidodiphosphate
"Guanylyl Imidodiphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
| Descriptor ID |
D006165
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| MeSH Number(s) |
D03.633.100.759.646.454.504.400 D13.695.667.454.504.400 D13.695.827.426.504.400
|
| Concept/Terms |
Guanylyl Imidodiphosphate- Guanylyl Imidodiphosphate
- Imidodiphosphate, Guanylyl
- Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
- Guanyl-5'-Imidodiphosphate
- Guanyl 5' Imidodiphosphate
- GMP-PNP
- P(NH)PPG
- GMP-P(NH)P
- Gpp(NH)p
|
Below are MeSH descriptors whose meaning is more general than "Guanylyl Imidodiphosphate".
Below are MeSH descriptors whose meaning is more specific than "Guanylyl Imidodiphosphate".
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Below are the most recent publications written about "Guanylyl Imidodiphosphate" by people in Profiles.
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Ras mediates the activation of phospholipase D by v-Src. J Biol Chem. 1995 Mar 17; 270(11):6006-9.
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Age-dependent changes in the subcellular distribution of rat brain mu-opioid receptors and GTP binding regulatory proteins. J Neurochem. 1991 Nov; 57(5):1470-7.
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Mechanosensitive adenylate cyclase activity in coronary vascular smooth muscle cells. Biochem Biophys Res Commun. 1990 Aug 31; 171(1):143-7.
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Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase? J Cyclic Nucleotide Protein Phosphor Res. 1986; 11(2):87-97.
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Nucleotide specificity of cardiac sarcoplasmic reticulum. GTP-induced calcium accumulation and GTPase activity. J Biol Chem. 1985 Aug 15; 260(17):9618-23.
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Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting. J Biol Chem. 1985 Jun 25; 260(12):7410-21.
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Relationship between the fluidity of the membrane lipids and the activity of the membrane-bound proteins: the effects of lidocaine on the adenylate cyclase activity of rat myocardium. Gen Pharmacol. 1983; 14(6):669-72.
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Developmental changes in the hormonal regulation of rat testis Sertoli cell adenylyl cyclase. Endocrinology. 1981 Oct; 109(4):1270-80.