Guanylyl Imidodiphosphate
"Guanylyl Imidodiphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
| Descriptor ID |
D006165
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| MeSH Number(s) |
D03.633.100.759.646.454.504.400 D13.695.667.454.504.400 D13.695.827.426.504.400
|
| Concept/Terms |
Guanylyl Imidodiphosphate- Guanylyl Imidodiphosphate
- Imidodiphosphate, Guanylyl
- Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
- Guanyl-5'-Imidodiphosphate
- Guanyl 5' Imidodiphosphate
- GMP-PNP
- P(NH)PPG
- GMP-P(NH)P
- Gpp(NH)p
|
Below are MeSH descriptors whose meaning is more general than "Guanylyl Imidodiphosphate".
Below are MeSH descriptors whose meaning is more specific than "Guanylyl Imidodiphosphate".
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Below are the most recent publications written about "Guanylyl Imidodiphosphate" by people in Profiles.
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Ras mediates the activation of phospholipase D by v-Src. J Biol Chem. 1995 Mar 17; 270(11):6006-9.
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Trypanosoma cruzi: effects of infection on receptor-mediated chronotropy and Ca2+ mobilization in rat cardiac myocytes. Exp Parasitol. 1994 Mar; 78(2):149-60.
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Opposing influences of dexamethasone and retinoic acid on adenylate cyclase activity in ROS 17/2.8 cells. Endocrinology. 1993 Jan; 132(1):261-8.
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Age-dependent changes in the subcellular distribution of rat brain mu-opioid receptors and GTP binding regulatory proteins. J Neurochem. 1991 Nov; 57(5):1470-7.
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Myocardial beta-adrenergic adenylate cyclase complex in a canine model of chagasic cardiomyopathy. Circ Res. 1991 Jul; 69(1):185-95.
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Mechanosensitive adenylate cyclase activity in coronary vascular smooth muscle cells. Biochem Biophys Res Commun. 1990 Aug 31; 171(1):143-7.
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The influence of EDTA on adenylate cyclase activity in membranes from rat and mouse myocardium. Biochim Biophys Acta. 1987 Nov 12; 931(2):234-41.
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Infection of L6E9 myoblasts with Trypanosoma cruzi alters adenylate cyclase activity and guanine nucleotide binding proteins. J Cell Physiol. 1987 Oct; 133(1):64-71.
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Do porins inhibit the macrophage phagocyting activity by stimulating the adenylate cyclase? J Cyclic Nucleotide Protein Phosphor Res. 1986; 11(2):87-97.
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Nucleotide specificity of cardiac sarcoplasmic reticulum. GTP-induced calcium accumulation and GTPase activity. J Biol Chem. 1985 Aug 15; 260(17):9618-23.