Guanosine 5'-O-(3-Thiotriphosphate)
"Guanosine 5'-O-(3-Thiotriphosphate)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Descriptor ID |
D016244
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MeSH Number(s) |
D02.886.765.380 D13.695.667.454.504.380 D13.695.827.426.504.380 D13.695.900.380
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Concept/Terms |
Guanosine 5'-O-(3-Thiotriphosphate)- Guanosine 5'-O-(3-Thiotriphosphate)
- GTP gamma S
- gamma S, GTP
- GTPgammaS
- Guanosine 5'-(gamma-S)Triphosphate
- gamma-Thio-GTP
- gamma Thio GTP
- Guanosine 5'-(3-O-Thio)Triphosphate
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Below are MeSH descriptors whose meaning is more general than "Guanosine 5'-O-(3-Thiotriphosphate)".
Below are MeSH descriptors whose meaning is more specific than "Guanosine 5'-O-(3-Thiotriphosphate)".
This graph shows the total number of publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in this website by year, and whether "Guanosine 5'-O-(3-Thiotriphosphate)" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1995 | 1 | 3 | 4 |
1996 | 1 | 2 | 3 |
1997 | 0 | 2 | 2 |
1998 | 0 | 1 | 1 |
1999 | 0 | 2 | 2 |
2000 | 0 | 2 | 2 |
2001 | 0 | 1 | 1 |
2003 | 0 | 3 | 3 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 3 | 3 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in Profiles.
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Effect of Iboga alkaloids on ?-opioid receptor-coupled G protein activation. PLoS One. 2013; 8(10):e77262.
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Novel role of NF-?B-p65 in antioxidant homeostasis in human kidney-2 cells. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1440-6.
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Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1174-80.
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A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons. J Neurochem. 2009 May; 109(3):867-78.
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Renal proximal tubules from old Fischer 344 rats grow into epithelial cells in cultures and exhibit increased oxidative stress and reduced D1 receptor function. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1326-31.
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Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F306-15.
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Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats. Kidney Int. 2007 Mar; 71(5):397-406.
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Loss of TRPV1-expressing sensory neurons reduces spinal mu opioid receptors but paradoxically potentiates opioid analgesia. J Neurophysiol. 2006 May; 95(5):3086-96.
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Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience. 2006; 138(4):1277-87.
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Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med. 2006 Jan 01; 40(1):13-20.