"Carcinoma, Lewis Lung" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Descriptor ID |
D018827
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| MeSH Number(s) |
C04.557.470.200.280 C04.619.230
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Carcinoma, Lewis Lung".
Below are MeSH descriptors whose meaning is more specific than "Carcinoma, Lewis Lung".
This graph shows the total number of publications written about "Carcinoma, Lewis Lung" by people in this website by year, and whether "Carcinoma, Lewis Lung" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carcinoma, Lewis Lung" by people in Profiles.
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Matrix metalloproteinase 12 promotes tumor propagation in the lung. J Thorac Cardiovasc Surg. 2018 05; 155(5):2164-2175.e1.
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Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia. J Biol Chem. 2015 Apr 24; 290(17):11177-87.
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Inhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-?B pathways with novel theanine derivatives. Oncotarget. 2014 Sep 30; 5(18):8528-43.
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Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Aug; 34(8):1697-703.
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WSX1 expression in tumors induces immune tolerance via suppression of effector immune cells. PLoS One. 2011 Apr 29; 6(4):e19072.
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Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth. Int J Cancer. 2008 Apr 15; 122(8):1738-44.
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Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. J Biol Chem. 2004 May 07; 279(19):19683-90.
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Inhibition of tumor growth by plasminogen-related protein-B. Anticancer Res. 2001 Jul-Aug; 21(4A):2287-91.
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NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity. Cancer Res. 2000 Dec 15; 60(24):6958-63.
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Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct; 6(5):287-93.