"Annexin A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the annexin family that is a substrate for a tyrosine kinase, ONCOGENE PROTEIN PP60(V-SRC). Annexin A2 occurs as a 36-KDa monomer and in a 90-KDa complex containing two subunits of annexin A2 and two subunits of S100 FAMILY PROTEIN P11. The monomeric form of annexin A2 was formerly referred to as calpactin I heavy chain.
Descriptor ID |
D017306
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MeSH Number(s) |
D12.776.157.125.050.060
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Concept/Terms |
Annexin A2- Annexin A2
- Annexin II, P36
- P36 Annexin II
- Lipocortin II
- Annexin II
- Capactin I Heavy Chain
|
Below are MeSH descriptors whose meaning is more general than "Annexin A2".
Below are MeSH descriptors whose meaning is more specific than "Annexin A2".
This graph shows the total number of publications written about "Annexin A2" by people in this website by year, and whether "Annexin A2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 |
2002 | 0 | 2 | 2 |
2003 | 2 | 0 | 2 |
2009 | 1 | 1 | 2 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2015 | 2 | 0 | 2 |
2016 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Annexin A2" by people in Profiles.
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HO-1 Interactors Involved in the Colonization of the Bone Niche: Role of ANXA2 in Prostate Cancer Progression. Biomolecules. 2020 03 18; 10(3).
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Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020 04; 222(4):376.e1-376.e17.
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S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma. Cancer Res. 2019 11 15; 79(22):5758-5768.
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High expression of Annexin A2 is associated with DNA repair, metabolic alteration, and worse survival in pancreatic ductal adenocarcinoma. Surgery. 2019 08; 166(2):150-156.
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RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery. Nanomedicine. 2017 04; 13(3):1183-1193.
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MIEN1, a novel interactor of Annexin A2, promotes tumor cell migration by enhancing AnxA2 cell surface expression. Mol Cancer. 2015 Aug 15; 14:156.
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Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer. Sci Signal. 2015 Aug 04; 8(388):ra77.
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Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012 Sep; 26(9):3715-27.
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Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS One. 2011 Apr 29; 6(4):e19390.
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Signal transducer and activator of transcription 6 (STAT6) is a novel interactor of annexin A2 in prostate cancer cells. Biochemistry. 2010 Mar 16; 49(10):2216-26.