"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
| Descriptor ID |
D007656
|
| MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
-
Early Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes. Neurocrit Care. 2022 12; 37(3):724-734.
-
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts. Elife. 2019 11 01; 8.
-
The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. Cell Rep. 2017 12 26; 21(13):3794-3806.
-
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. J Biol Chem. 2017 08 25; 292(34):14240-14249.
-
A scalable lysyl hydroxylase 2 expression system and luciferase-based enzymatic activity assay. Arch Biochem Biophys. 2017 03 15; 618:45-51.
-
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017 02 02; 542(7639):119-123.
-
Loss of Nardilysin, a Mitochondrial Co-chaperone for a-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. 2017 Jan 04; 93(1):115-131.
-
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. mBio. 2016 11 15; 7(6).
-
Targeting isocitrate dehydrogenase (IDH) in cancer. Discov Med. 2016 05; 21(117):373-80.
-
Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Rep. 2015 Dec 22; 13(11):2353-2361.