"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
| Descriptor ID |
D007656
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| MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
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Early Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes. Neurocrit Care. 2022 12; 37(3):724-734.
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The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. Cell Rep. 2017 12 26; 21(13):3794-3806.
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Loss of Nardilysin, a Mitochondrial Co-chaperone for a-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. 2017 Jan 04; 93(1):115-131.
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Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. mBio. 2016 11 15; 7(6).
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Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases. J Biomol Screen. 2009 Jul; 14(6):627-35.
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Chemo- and stereoselective reaction between alkyl isocyanides and dimethyl 1,3-acetonedicarbocxylate in the presence of acetylenic esters. Mol Divers. 2007 May; 11(2):101-5.
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Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hear Res. 2007 Jun; 228(1-2):95-104.
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First-pass metabolism limits the intestinal absorption of enteral alpha-ketoglutarate in young pigs. J Nutr. 2006 Nov; 136(11):2779-84.
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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell. 2005 Aug; 8(2):143-53.
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Net portal absorption of enterally fed alpha-ketoglutarate is limited in young pigs. J Nutr. 2002 Nov; 132(11):3383-6.