Receptor, Serotonin, 5-HT1B
"Receptor, Serotonin, 5-HT1B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
| Descriptor ID |
D044302
|
| MeSH Number(s) |
D12.776.543.750.670.800.100.150 D12.776.543.750.695.800.100.150 D12.776.543.750.720.670.100.500 D12.776.543.750.720.850.100.150
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| Concept/Terms |
Receptor, Serotonin, 5-HT1B- Receptor, Serotonin, 5-HT1B
- 5-HT1B Receptor
- 5 HT1B Receptor
- Receptor, 5-HT1B
- 5-Hydroxytryptamine 1B Receptor
- 1B Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptor
- 5-Hydroxytryptamine 1B Receptors
- 1B Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptors
- Receptors, 5-Hydroxytryptamine 1B
- Receptor, 5-Hydroxytryptamine 1B
- Receptor, 5 Hydroxytryptamine 1B
- Serotonin 1B Receptor
- Receptor, Serotonin 1B
- 5-HT1Dbeta Receptor
- 5 HT1Dbeta Receptor
- Receptor, 5-HT1Dbeta
- Receptor, Serotonin Type 1Dbeta
- Serotonin 1Dbeta Receptors
- Receptors, Serotonin 1Dbeta
- Serotonin 1Dbeta Receptor
- Receptor, Serotonin 1Dbeta
- Serotonin 1D Beta Receptor
- 5-HT(1B) Receptor
- 5-HT(1Dbeta) Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1B".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.670.800.100.150]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.695.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.695.800.100.150]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Presynaptic [D12.776.543.750.720.670]
- Autoreceptors [D12.776.543.750.720.670.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.670.100.500]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.850.100.150]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1B".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1B" by people in this website by year, and whether "Receptor, Serotonin, 5-HT1B" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1B" by people in Profiles.
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Gene-specific cell labeling using MiMIC transposons. Nucleic Acids Res. 2015 Apr 30; 43(8):e56.
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Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. PLoS One. 2014; 9(9):e110067.
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Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. PLoS One. 2014; 9(8):e105245.
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FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin. J Clin Invest. 2012 Oct; 122(10):3490-503.
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The effects of glycogen synthase kinase-3beta in serotonin neurons. PLoS One. 2012; 7(8):e43262.
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Glycogen synthase kinase-3? is a functional modulator of serotonin-1B receptors. Mol Pharmacol. 2011 Jun; 79(6):974-86.
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Association between the 5-HTR1B gene polymorphisms and alcohol dependence in a Han Chinese population. Brain Res. 2011 Feb 28; 1376:1-9.
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Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Ann N Y Acad Sci. 2010 Feb; 1187:184-207.
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Differential coupling of serotonin 5-HT1A and 5-HT1B receptors to activation of ERK2 and inhibition of adenylyl cyclase in transfected CHO cells. J Neurochem. 1999 Jul; 73(1):162-8.