"Methylmalonyl-CoA Mutase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. EC 5.4.99.2.
| Descriptor ID |
D008765
|
| MeSH Number(s) |
D08.811.399.520.625
|
| Concept/Terms |
Methylmalonyl-CoA Mutase- Methylmalonyl-CoA Mutase
- Methylmalonyl CoA Mutase
- Mutase, Methylmalonyl-CoA
- Methylmalonyl-CoA Isomerase
- Isomerase, Methylmalonyl-CoA
- Methylmalonyl CoA Isomerase
|
Below are MeSH descriptors whose meaning is more general than "Methylmalonyl-CoA Mutase".
Below are MeSH descriptors whose meaning is more specific than "Methylmalonyl-CoA Mutase".
This graph shows the total number of publications written about "Methylmalonyl-CoA Mutase" by people in this website by year, and whether "Methylmalonyl-CoA Mutase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Methylmalonyl-CoA Mutase" by people in Profiles.
-
Mutations Affecting Cellular Levels of Cobalamin (Vitamin B12) Confer Tolerance to Bactericidal Antibiotics in Burkholderia cenocepacia. J Microbiol Biotechnol. 2024 Aug 28; 34(8):1609-1616.
-
Pre-implantation genetic diagnosis in an Iranian family with a novel mutation in MUT gene. BMC Med Genet. 2020 02 03; 21(1):22.
-
Next generation sequencing of patients with mut methylmalonic aciduria: Validation of somatic cell studies and identification of 16 novel mutations. Mol Genet Metab. 2016 08; 118(4):264-71.
-
Noninvasive prenatal diagnosis in a fetus at risk for methylmalonic acidemia. Genet Med. 2014 Jul; 16(7):564-7.
-
Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae. Biochem Med Metab Biol. 1993 Oct; 50(2):135-44.
-
Linkage relationships of the human methylmalonyl CoA mutase to the HLA and D6S4 loci on chromosome 6. Genomics. 1988 Nov; 3(4):396-8.
-
Mapping of human methylmalonyl CoA mutase (MUT) locus on chromosome 6. Am J Hum Genet. 1988 Jun; 42(6):839-46.