Combinatorial Chemistry Techniques
"Combinatorial Chemistry Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.
| Descriptor ID |
D020650
|
| MeSH Number(s) |
E05.197.312 J01.897.836.249.249
|
| Concept/Terms |
Combinatorial Chemistry Techniques- Combinatorial Chemistry Techniques
- Techniques, Combinatorial Chemistry
- Chemistry Technique, Combinatorial
- Combinatorial Chemistry Technique
- Technics, Combinatorial Chemistry
- Chemistry Technic, Combinatorial
- Chemistry Technics, Combinatorial
- Combinatorial Chemistry Technic
- Combinatorial Chemistry Technics
- Technic, Combinatorial Chemistry
- Chemistry Techniques, Combinatorial
- Technique, Combinatorial Chemistry
|
Below are MeSH descriptors whose meaning is more general than "Combinatorial Chemistry Techniques".
Below are MeSH descriptors whose meaning is more specific than "Combinatorial Chemistry Techniques".
This graph shows the total number of publications written about "Combinatorial Chemistry Techniques" by people in this website by year, and whether "Combinatorial Chemistry Techniques" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Combinatorial Chemistry Techniques" by people in Profiles.
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Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library. Bioorg Med Chem. 2021 10 15; 48:116387.
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Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):16782-16789.
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Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat Biotechnol. 2019 10; 37(10):1209-1216.
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Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections. ACS Comb Sci. 2019 02 11; 21(2):75-82.
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PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation. Sci Transl Med. 2016 12 14; 8(369):369ra175.
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Discovery and horizontal follow-up of an autoantibody signature in human prostate cancer. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2515-20.
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Solution-phase synthesis of a diverse library of benzisoxazoles utilizing the [3 + 2] cycloaddition of in situ-generated nitrile oxides and arynes. ACS Comb Sci. 2013 Apr 08; 15(4):193-201.
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Synthesis and characterization of a novel inhibitor of C-reactive protein-mediated proinflammatory effects. Metab Syndr Relat Disord. 2013 Jun; 11(3):177-84.
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A strategy for modulation of enzymes in the ubiquitin system. Science. 2013 Feb 01; 339(6119):590-5.
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3'-Modified oligodeoxyribonucleotides for the study of 2-deoxyribose damage in DNA. Bioorg Med Chem Lett. 2013 Feb 01; 23(3):854-9.