"Tubulin Modulators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.
| Descriptor ID |
D050257
|
| MeSH Number(s) |
D27.505.519.593.249.500
|
| Concept/Terms |
Tubulin Modulators- Tubulin Modulators
- Modulators, Tubulin
- Microtubule Modulators
- Modulators, Microtubule
Tubulin Promoters- Tubulin Promoters
- Promoters, Tubulin
- Tubulin Polymerization Promoters
- Polymerization Promoters, Tubulin
- Promoters, Tubulin Polymerization
Tubulin Inhibitors- Tubulin Inhibitors
- Inhibitors, Tubulin
- Tubulin Polymerization Inhibitors
- Inhibitors, Tubulin Polymerization
- Polymerization Inhibitors, Tubulin
|
Below are MeSH descriptors whose meaning is more general than "Tubulin Modulators".
Below are MeSH descriptors whose meaning is more specific than "Tubulin Modulators".
This graph shows the total number of publications written about "Tubulin Modulators" by people in this website by year, and whether "Tubulin Modulators" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 3 | 2 | 5 |
| 2009 | 2 | 3 | 5 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tubulin Modulators" by people in Profiles.
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Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors. Bioorg Chem. 2020 12; 105:104447.
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Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group. Pediatr Rheumatol Online J. 2020 Apr 15; 18(1):31.
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Microtubule depolymerization attenuates WNT4/CaMKIIa signaling in mouse uterus and leads to implantation failure. Reproduction. 2019 07; 158(1):47-59.
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Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer. Cancer Chemother Pharmacol. 2019 10; 84(4):669-677.
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Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. Nat Commun. 2018 02 02; 9(1):476.
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Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells. Mol Cancer Ther. 2017 09; 16(9):1819-1830.
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Discovery and Optimization of Novel 5-Indolyl-7-arylimidazo[1,2-a]pyridine-8-carbonitrile Derivatives as Potent Antitubulin Agents Targeting Colchicine-binding Site. Sci Rep. 2017 02 27; 7:43398.
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A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells. Sci Rep. 2016 10 17; 6:34653.
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Langerhans Cell Histiocytosis of the Maxillary Sinus. Clin Pediatr (Phila). 2017 02; 56(2):184-186.
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Monomethyl Auristatin E Phosphate Inhibits Human Prostate Cancer Growth. Prostate. 2016 11; 76(15):1420-30.