Hepatocyte Nuclear Factor 1-alpha
"Hepatocyte Nuclear Factor 1-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hepatocyte nuclear factor 1-alpha is a transcription factor found in the LIVER; PANCREAS; and KIDNEY that regulates HOMEOSTASIS of GLUCOSE.
| Descriptor ID |
D051538
|
| MeSH Number(s) |
D12.776.260.262.500.500 D12.776.260.400.218.500 D12.776.660.352.500.500 D12.776.930.318.500.500
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1-alpha- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1 alpha
- LFB1 Transcription Factor
- Liver-Specific Transcription Factor LF-B1
- Liver Specific Transcription Factor LF B1
- Albumin Proximal Factor
- HNF-1alpha
- HNF 1alpha
- Hepatocyte Nuclear Factor 1alpha
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1-alpha".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1-alpha".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 4 | 4 |
| 2020 | 1 | 1 | 2 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in Profiles.
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Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1. Proc Natl Acad Sci U S A. 2025 Jan 14; 122(2):e2418985122.
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Transcription factor TCF1 binds to ROR?t and orchestrates a regulatory network that determines homeostatic Th17 cell state. Immunity. 2024 11 12; 57(11):2565-2582.e6.
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Variants of Unknown Significance in Maturity-Onset Diabetes of the Young: High Rate of Conundrum Resolution via Variants of Unknown Significance Reanalysis. Horm Res Paediatr. 2025; 98(5):524-531.
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Hepatocyte nuclear factor 1 alpha influences pancreatic cancer growth and metastasis. Sci Rep. 2020 11 19; 10(1):20225.
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Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12182-12191.
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An intra-tumoral niche maintains and differentiates stem-like CD8 T cells. Nature. 2019 12; 576(7787):465-470.
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Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection. Immunity. 2019 12 17; 51(6):1043-1058.e4.
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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019 10; 51(10):1459-1474.
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Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy. JCI Insight. 2019 04 23; 5.
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Monogenic diabetes in overweight and obese youth diagnosed with type 2 diabetes: the TODAY clinical trial. Genet Med. 2018 06; 20(6):583-590.