Hepatocyte Nuclear Factor 1-beta
"Hepatocyte Nuclear Factor 1-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only weakly expressed in the LIVER. Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.
| Descriptor ID |
D051539
|
| MeSH Number(s) |
D12.776.260.262.500.750 D12.776.260.400.218.750 D12.776.660.352.500.750 D12.776.930.318.500.750
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1-beta- Hepatocyte Nuclear Factor 1-beta
- Hepatocyte Nuclear Factor 1 beta
- Liver Specific Transcription Factor LF-B3
- Liver Specific Transcription Factor LF B3
- Variant Hepatic Nuclear Factor 1
- HNF-1beta
- HNF 1beta
- Hepatocyte Nuclear Factor-1beta
- Hepatocyte Nuclear Factor 1beta
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1-beta".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1-beta".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1-beta" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1-beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hepatocyte Nuclear Factor 1-beta" by people in Profiles.
-
HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas. Cancer Res. 2017 10 01; 77(19):5313-5326.
-
Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene. Genet Med. 2017 04; 19(4):412-420.
-
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun. 2013; 4:1628.
-
Clinical spectrum associated with recurrent genomic rearrangements in chromosome 17q12. Eur J Hum Genet. 2010 Mar; 18(3):278-84.
-
Regulation of hepatocyte nuclear factor 1 activity by wild-type and mutant hepatitis B virus X proteins. J Virol. 2002 Jun; 76(12):5875-81.