"Receptor, Adenosine A2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of other tissues. It is generally considered to be a receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.
| Descriptor ID |
D043705
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.200.100 D12.776.543.750.720.700.700.200.100
|
| Concept/Terms |
Receptor, Adenosine A2A- Receptor, Adenosine A2A
- A2A Receptor, Adenosine
- Adenosine A(2A) Receptor
- Adenosine A2A Receptor
- Adenosine A2A Receptors
- A2A Receptors, Adenosine
- Receptors, Adenosine A2A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptors, Adenosine A2 [D12.776.543.750.695.700.700.200]
- Receptor, Adenosine A2A [D12.776.543.750.695.700.700.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptors, Adenosine A2 [D12.776.543.750.720.700.700.200]
- Receptor, Adenosine A2A [D12.776.543.750.720.700.700.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A2A".
This graph shows the total number of publications written about "Receptor, Adenosine A2A" by people in this website by year, and whether "Receptor, Adenosine A2A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Receptor, Adenosine A2A" by people in Profiles.
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Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiation. Pharmacol Res. 2025 11; 221:108012.
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Endothelial adenosine receptor 2A loss alleviates diabetic vascular calcification by blocking CREB1-SNAI1-driven EndMT. Pharmacol Res. 2025 11; 221:107981.
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Limonene-induced activation of A2A adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma. Purinergic Signal. 2020 09; 16(3):415-426.
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Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy. Science. 2020 09 18; 369(6510):1481-1489.
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CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease. J Autoimmun. 2016 08; 72:102-12.
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Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2078-85.
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8-(Furan-2-yl)-3-phenethylthiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione as novel, selective and potent adenosine A(2A) receptor antagonist. Neurosci Lett. 2014 Jan 13; 558:203-7.
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Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists. Bioorg Med Chem. 2013 Oct 01; 21(19):6077-83.
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Upregulation of adenosine A2A receptors induced by atypical antipsychotics and its correlation with sensory gating in schizophrenia patients. Psychiatry Res. 2012 Dec 30; 200(2-3):126-32.
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Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists. Bioorg Med Chem Lett. 2010 Feb 01; 20(3):1214-8.