"Receptor, Adenosine A2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of adenosine A2 receptors found in LEUKOCYTES, the SPLEEN, the THYMUS and a variety of other tissues. It is generally considered to be a receptor for ADENOSINE that couples to the GS, STIMULATORY G-PROTEIN.
| Descriptor ID |
D043705
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.200.100 D12.776.543.750.720.700.700.200.100
|
| Concept/Terms |
Receptor, Adenosine A2A- Receptor, Adenosine A2A
- A2A Receptor, Adenosine
- Adenosine A(2A) Receptor
- Adenosine A2A Receptor
- Adenosine A2A Receptors
- A2A Receptors, Adenosine
- Receptors, Adenosine A2A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptors, Adenosine A2 [D12.776.543.750.695.700.700.200]
- Receptor, Adenosine A2A [D12.776.543.750.695.700.700.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptors, Adenosine A2 [D12.776.543.750.720.700.700.200]
- Receptor, Adenosine A2A [D12.776.543.750.720.700.700.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A2A".
This graph shows the total number of publications written about "Receptor, Adenosine A2A" by people in this website by year, and whether "Receptor, Adenosine A2A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 0 | 3 |
| 2014 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2020 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Adenosine A2A" by people in Profiles.
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A2A receptor signaling drives cisplatin-mediated hippocampal neurotoxicity and cognitive defects in mice. Purinergic Signal. 2023 12; 19(4):591-593.
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Adenosine A2a Receptor Antagonism Restores Additive Cytotoxicity by Cytotoxic T Cells in Metabolically Perturbed Tumors. Cancer Immunol Res. 2022 12 02; 10(12):1462-1474.
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Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. JCI Insight. 2020 09 03; 5(17).
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Limonene-induced activation of A2A adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma. Purinergic Signal. 2020 09; 16(3):415-426.
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Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy. Science. 2020 09 18; 369(6510):1481-1489.
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Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors. J Exp Med. 2017 01; 214(1):107-123.
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Macrophage A2A Adenosine Receptors Are Essential to Protect from Progressive Kidney Injury. Am J Pathol. 2016 10; 186(10):2601-13.
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CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease. J Autoimmun. 2016 08; 72:102-12.
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Adenosine regulates the proinflammatory signaling function of thrombin in endothelial cells. J Cell Physiol. 2014 Sep; 229(9):1292-300.
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Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2078-85.