Adenosine A2 Receptor Antagonists
"Adenosine A2 Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that selectively bind to and block the activation of ADENOSINE A2 RECEPTORS.
| Descriptor ID |
D058917
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| MeSH Number(s) |
D27.505.519.625.725.400.100.200 D27.505.696.577.725.400.100.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Adenosine A2 Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Adenosine A2 Receptor Antagonists".
This graph shows the total number of publications written about "Adenosine A2 Receptor Antagonists" by people in this website by year, and whether "Adenosine A2 Receptor Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Adenosine A2 Receptor Antagonists" by people in Profiles.
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Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiation. Pharmacol Res. 2025 Nov; 221:108012.
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Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2078-85.
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Adenosine A2B receptor and hyaluronan modulate pulmonary hypertension associated with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2013 Dec; 49(6):1038-47.
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8-(Furan-2-yl)-3-phenethylthiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione as novel, selective and potent adenosine A(2A) receptor antagonist. Neurosci Lett. 2014 Jan 13; 558:203-7.
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Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists. Bioorg Med Chem. 2013 Oct 01; 21(19):6077-83.
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Attenuation of the side effect profile of regadenoson: a randomized double-blinded placebo-controlled study with aminophylline in patients undergoing myocardial perfusion imaging. "The ASSUAGE trial". J Nucl Cardiol. 2012 Jun; 19(3):448-57.
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Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A(2A) receptor antagonist. Neurosci Lett. 2011 Jan 13; 488(1):1-5.
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Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists. Bioorg Med Chem. 2010 Apr 01; 18(7):2491-500.
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Synthesis of novel 7-imino-2-thioxo-3,7-dihydro-2H-thiazolo [4,5-d] pyrimidine derivatives as adenosine A2A receptor antagonists. Bioorg Med Chem Lett. 2010 Feb 01; 20(3):1214-8.
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In silico study of naphtha [1, 2-d] thiazol-2-amine with adenosine A 2A receptor and its role in antagonism of haloperidol-induced motor impairments in mice. Neurosci Lett. 2009 Oct 09; 463(3):215-8.