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p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.
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p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.
p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell. 2012 Jun 12; 21(6):793-806.
View in:
PubMed
subject areas
Aging
Animals
Antibiotics, Antineoplastic
Apoptosis
Blotting, Western
Breast Neoplasms
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p21
Cytokines
Doxorubicin
Gene Expression Regulation, Neoplastic
Humans
Mammary Neoplasms, Experimental
Mammary Tumor Virus, Mouse
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Mutation
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Treatment Outcome
Tumor Burden
Tumor Suppressor Protein p53
Wnt1 Protein
authors with profiles
GUILLERMINA LOZANO
ADEL K EL-NAGGAR
VINOD PANT
YI LI