DEBORAH VELA

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    1. Buja LM, Zhao B, Vela D, Segura A, Narula N. Pathobiology of Aortic Aneurysms and Dissections: Synthesis of Recent Investigations and Evolving Insights. JACC Adv. 2025 May; 4(5):101682. PMID: 40286354; PMCID: PMC12101538.
      Citations:    
    2. Young P, Nolen D, Milner TE, Gruslova A, Vela D, Buja LM, Diaz Sanmartin LA, Rad P, Feldman MD. Histology-Grounded Automated Plaque Subtype Segmentation in Intravascular Optical Coherence Tomography. J Soc Cardiovasc Angiogr Interv. 2025 Mar; 4(3Part B):102524. PMID: 40230683; PMCID: PMC11993869.
      Citations:    
    3. Devkota L, Zhang C, Vela D, Sarkar P, Bhandari P, Starosolski Z, Menon R, Milewicz DM, Shen YH, LeMaire SA, Ghaghada KB. Nanoparticle contrast-enhanced computed tomography of sporadic aortic aneurysm and dissection: Effect of nanoparticle size and contrast agent dose. Theranostics. 2025; 15(8):3462-3473. PMID: 40093886; PMCID: PMC11905125.
      Citations:    Fields:    
    4. Kansul F, Vela D, Csore J, Benfor B, Suarez S, Dua A, Roy TL. Evaluation of sex-based differences in below-the-knee plaque histology in patients who underwent amputation for chronic limb-threatening ischemia. JVS Vasc Sci. 2025; 6:100269. PMID: 39896044; PMCID: PMC11787704.
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    5. Yang S, Zemzemi C, Escudero DS, Vela DC, Haworth KJ, Holland CK. Histotripsy and Catheter-Directed Lytic: Efficacy in Highly Retracted Porcine Clots In Vitro. Ultrasound Med Biol. 2024 08; 50(8):1167-1177. PMID: 38777639.
      Citations:    
    6. Benfor B, Csore J, Vela DC, Montero-Baker M, Roy TL. Magnetic Resonance Imaging and Histological Insights Into Deep Venous Arterialisation. EJVES Vasc Forum. 2024; 61:121-125. PMID: 38884072; PMCID: PMC11177077.
      Citations:    
    7. Gruslova AB, Katta N, Nolen D, Jenney S, Vela D, Buja M, Cilingiroglu M, Seddighi Y, Han HC, Milner TE, Feldman MD. Intravascular laser lithotripsy for calcium fracture in human coronary arteries. EuroIntervention. 2023 Dec 18; 19(11):e913-e922. PMID: 38060282; PMCID: PMC10722992.
      Citations:    Fields:    Translation:Humans
    8. Gruslova AB, Singh S, Hoyt T, Vela D, Vengrenyuk Y, Buja LM, Litovsky S, Michalek J, Maehara A, Kini A, Akasaka T, Garcia-Garcia HM, Jang IK, Dijkstra J, Raber L, Milner TE, Feldman MD. Accuracy of OCT Core Labs in Identifying?Vulnerable Plaque. JACC Cardiovasc Imaging. 2024 Apr; 17(4):448-450. PMID: 37943235.
      Citations:    Fields:    
    9. Barker CM, Meduri CU, Fail PS, Chambers JW, Solet DJ, Kriegel JM, Vela DC, Feldt K, Pate TD, Patel AP, Shaburishvili T. Feasibility of a No-Implant Approach to Interatrial Shunts: Preclinical and Early Clinical Studies. Struct Heart. 2022 Aug; 6(4):100078. PMID: 37288335; PMCID: PMC10242572.
      Citations:    
    10. Klegerman ME, Moody MR, Huang SL, Peng T, Laing ST, Govindarajan V, Danila D, Tahanan A, Rahbar MH, Vela D, Genstler C, Haworth KJ, Holland CK, McPherson DD, Kee PH. Demonstration of ultrasound-mediated therapeutic delivery of fibrin-targeted pioglitazone-loaded echogenic liposomes into the arterial bed for attenuation of peri-stent restenosis. J Drug Target. 2023 01; 31(1):109-118. PMID: 35938912.
      Citations:    
    11. Zemzemi C, Phillips M, Vela DC, Hilvert NA, Racadio JM, Bader KB, Haworth KJ, Holland CK. Effect of Thrombin and Incubation Time on Porcine Whole Blood Clot Elasticity and Recombinant Tissue Plasminogen Activator Susceptibility. Ultrasound Med Biol. 2022 08; 48(8):1567-1578. PMID: 35644763; PMCID: PMC9247038.
      Citations:    
    12. Davogustto GE, Salazar RL, Vasquez HG, Karlstaedt A, Dillon WP, Guthrie PH, Martin JR, Vitrac H, De La Guardia G, Vela D, Ribas-Latre A, Baumgartner C, Eckel-Mahan K, Taegtmeyer H. Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy. J Mol Cell Cardiol. 2021 09; 158:115-127. PMID: 34081952; PMCID: PMC8630806.
      Citations: 4     Fields:    Translation:AnimalsCells
    13. Li K, Wagner L, Moctezuma-Ramirez A, Vela D, Perin E. A Robust Percutaneous Myocardial Infarction Model in Pigs and Its Effect on Left Ventricular Function. J Cardiovasc Transl Res. 2021 12; 14(6):1075-1084. PMID: 33834389.
      Citations:    
    14. Ghaghada KB, Ren P, Devkota L, Starosolski Z, Zhang C, Vela D, Stupin IV, Tanifum EA, Annapragada AV, Shen YH, LeMaire SA. Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography. Arterioscler Thromb Vasc Biol. 2021 04; 41(4):1534-1548. PMID: 33535789; PMCID: PMC7990703.
      Citations:    Fields:    Translation:Animals
    15. Li K, Vela D, Migliati E, da Graca Cabreira M, Wang X, Buja LM, Perin EC. Pilot Study of Endovascular Delivery of Mesenchymal Stromal Cells in the Aortic Wall in a Pig Model. Cell Transplant. 2021 Jan-Dec; 30:9636897211010652. PMID: 33938770; PMCID: PMC8114770.
      Citations:    
    16. Bec J, Vela D, Phipps JE, Agung M, Unger J, Margulies KB, Southard JA, Buja LM, Marcu L. Label-Free Visualization and Quantification of Biochemical Markers of Atherosclerotic Plaque Progression Using Intravascular Fluorescence Lifetime. JACC Cardiovasc Imaging. 2021 09; 14(9):1832-1842. PMID: 33221238; PMCID: PMC8116358.
      Citations:    
    17. Baruah V, Zahedivash A, Hoyt T, McElroy A, Vela D, Buja LM, Cabe A, Oglesby M, Estrada A, Antonik P, Milner TE, Feldman MD. Automated Coronary Plaque Characterization With Intravascular Optical Coherence Tomography and Smart-Algorithm Approach: Virtual Histology OCT. JACC Cardiovasc Imaging. 2020 08; 13(8):1848-1850. PMID: 32305483.
      Citations: 1     Fields:    Translation:Humans
    18. Kee PH, Moody MR, Huang SL, Kim H, Yin X, Peng T, Laing ST, Klegerman ME, Rahbar MH, Vela D, Genstler C, Haworth KJ, Holland CK, McPherson DD. Stabilizing Peri-Stent Restenosis Using a Novel Therapeutic Carrier. JACC Basic Transl Sci. 2020 Jan; 5(1):1-11. PMID: 32043017; PMCID: PMC7000871.
      Citations:    
    19. Rico-Jimenez JJ, Campos-Delgado DU, Buja LM, Vela D, Jo JA. Intravascular optical coherence tomography method for automated detection of macrophage infiltration within atherosclerotic coronary plaques. Atherosclerosis. 2019 11; 290:94-102. PMID: 31604172; PMCID: PMC6878982.
      Citations:    
    20. Rico-Jimenez JJ, Serafino MJ, Shrestha S, Chen X, Kim W, Adame J, Buja LM, Vela D, Applegate BE, Jo JA. Automated detection of superficial macrophages in atherosclerotic plaques using autofluorescence lifetime imaging. Atherosclerosis. 2019 06; 285:120-127. PMID: 31051415; PMCID: PMC6536321.
      Citations:    
    21. Phipps JE, Hoyt T, Vela D, Wang T, Michalek JE, Buja LM, Jang IK, Milner TE, Feldman MD. Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images: Effects of Light Scattering. Circ Cardiovasc Interv. 2016 07; 9(7). PMID: 27406987; PMCID: PMC4946571.
      Citations: 14     Fields:    Translation:Humans
    22. Aboshady I, Raad I, Vela D, Hassan M, Aboshady Y, Safi HJ, Buja LM, Khalil KG. Prevention of perioperative vascular prosthetic infection with a novel triple antimicrobial-bonded arterial graft. J Vasc Surg. 2016 Dec; 64(6):1805-1814. PMID: 26626182.
      Citations: 3     Fields:    Translation:Animals
    23. Wang T, McElroy A, Halaney D, Vela D, Fung E, Hossain S, Phipps J, Wang B, Yin B, Feldman MD, Milner TE. Detection of plaque structure and composition using OCT combined with two-photon luminescence (TPL) imaging. Lasers Surg Med. 2015 Aug; 47(6):485-94. PMID: 26018531.
      Citations:    
    24. Vela D, Gahremanpour A, Buja LM. Method for sectioning and sampling hearts for histologic evaluation after delivery of biological agents by transendocardial injection. Cardiovasc Pathol. 2015 Sep-Oct; 24(5):304-9. PMID: 26002556.
      Citations:    
    25. Wang T, McElroy A, Halaney D, Vela D, Fung E, Hossain S, Phipps J, Wang B, Yin B, Feldman MD, Milner TE. Dual-modality fiber-based OCT-TPL imaging system for simultaneous microstructural and molecular analysis of atherosclerotic plaques. Biomed Opt Express. 2015 May 01; 6(5):1665-78. PMID: 26137371; PMCID: PMC4467709.
      Citations:    
    26. Kim H, Kee PH, Rim Y, Moody MR, Klegerman ME, Vela D, Huang SL, McPherson DD, Laing ST. Nitric Oxide-Enhanced Molecular Imaging of Atheroma using Vascular Cellular Adhesion Molecule 1-Targeted Echogenic Immunoliposomes. Ultrasound Med Biol. 2015 Jun; 41(6):1701-10. PMID: 25819469; PMCID: PMC4426087.
      Citations:    
    27. Phipps JE, Vela D, Hoyt T, Halaney DL, Mancuso JJ, Buja LM, Asmis R, Milner TE, Feldman MD. Macrophages and intravascular OCT bright spots: a quantitative study. JACC Cardiovasc Imaging. 2015 Jan; 8(1):63-72. PMID: 25499133; PMCID: PMC4297553.
      Citations: 28     Fields:    Translation:HumansCells
    28. Kee PH, Kim H, Huang S, Laing ST, Moody MR, Vela D, Klegerman ME, McPherson DD. Nitric oxide pretreatment enhances atheroma component highlighting in vivo with intercellular adhesion molecule-1-targeted echogenic liposomes. Ultrasound Med Biol. 2014 Jun; 40(6):1167-76. PMID: 24613216; PMCID: PMC4011946.
      Citations:    
    29. Kim H, Kee PH, Rim Y, Moody MR, Klegerman ME, Vela D, Huang SL, McPherson DD, Laing ST. Nitric oxide improves molecular imaging of inflammatory atheroma using targeted echogenic immunoliposomes. Atherosclerosis. 2013 Dec; 231(2):252-60. PMID: 24267236; PMCID: PMC3871611.
      Citations:    
    30. Gahremanpour A, Vela D, Zheng Y, Silva GV, Fodor W, Cardoso CO, Baimbridge F, Fernandes MR, Buja LM, Perin EC. Xenotransplantation of human unrestricted somatic stem cells in a pig model of acute myocardial infarction. Xenotransplantation. 2013 Mar-Apr; 20(2):110-22. PMID: 23489741.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    31. Sutton JT, Ivancevich NM, Perrin SR, Vela DC, Holland CK. Clot retraction affects the extent of ultrasound-enhanced thrombolysis in an ex?vivo porcine thrombosis model. Ultrasound Med Biol. 2013 May; 39(5):813-24. PMID: 23453629; PMCID: PMC3618502.
      Citations:    
    32. Bhavane R, Badea C, Ghaghada KB, Clark D, Vela D, Moturu A, Annapragada A, Johnson GA, Willerson JT, Annapragada A. Dual-energy computed tomography imaging of atherosclerotic plaques in a mouse model using a liposomal-iodine nanoparticle contrast agent. Circ Cardiovasc Imaging. 2013 Mar 01; 6(2):285-94. PMID: 23349231; PMCID: PMC3760185.
      Citations: 25     Fields:    Translation:AnimalsCells
    33. Zheng Y, Sampaio LC, Li K, Silva GV, Cabreira-Hansen M, Vela D, Segura AM, Perin EC, Bov? C. Safety and feasibility of mapping and stem cell delivery in the presence of an implanted left ventricular assist device: a preclinical investigation in sheep. Tex Heart Inst J. 2013; 40(3):229-34. PMID: 23914010; PMCID: PMC3709201.
      Citations: 5     Fields:    Translation:Animals
    34. Harmancey R, Lam TN, Lubrano GM, Guthrie PH, Vela D, Taegtmeyer H. Insulin resistance improves metabolic and contractile efficiency in stressed rat heart. FASEB J. 2012 Aug; 26(8):3118-26. PMID: 22611083; PMCID: PMC3405268.
      Citations: 22     Fields:    Translation:AnimalsCells
    35. Aboshady I, Raad I, Shah AS, Vela D, Dvorak T, Safi HJ, Buja LM, Khalil KG. A pilot study of a triple antimicrobial-bonded Dacron graft for the prevention of aortic graft infection. J Vasc Surg. 2012 Sep; 56(3):794-801. PMID: 22579134.
      Citations: 8     Fields:    Translation:Animals
    36. Ramani R, Vela D, Segura A, McNamara D, Lemster B, Samarendra V, Kormos R, Toyoda Y, Bermudez C, Frazier OH, Moravec CS, Gorcsan J, Taegtmeyer H, McTiernan CF. A micro-ribonucleic acid signature associated with recovery from assist device support in 2 groups of patients with severe heart failure. J Am Coll Cardiol. 2011 Nov 22; 58(22):2270-8. PMID: 22093502; PMCID: PMC3226759.
      Citations: 20     Fields:    Translation:HumansCells
    37. Ahmed A, Gondi S, Cox C, Zheng M, Mohammed A, Stupin IV, Wang S, Vela D, Brewer A, Elayda MA, Buja LM, Ward Casscells S, Wilson JM. Body temperature circadian rhythm variability corresponds to left ventricular systolic dysfunction in decompensated cardiomyopathic hamsters. J Card Fail. 2011 Nov; 17(11):937-43. PMID: 22041331.
      Citations: 1     Fields:    Translation:Animals
    38. Hitchcock KE, Ivancevich NM, Haworth KJ, Caudell Stamper DN, Vela DC, Sutton JT, Pyne-Geithman GJ, Holland CK. Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound Med Biol. 2011 Aug; 37(8):1240-51. PMID: 21723448; PMCID: PMC4025997.
      Citations:    
    39. Perin EC, Silva GV, Vela DC, Zheng Y, Baimbridge F, Gahremanpour A, Quan X, Hahn W, Kim J, Wood K, Kitamura M. Human hepatocyte growth factor (VM202) gene therapy via transendocardial injection in a pig model of chronic myocardial ischemia. J Card Fail. 2011 Jul; 17(7):601-11. PMID: 21703533.
      Citations: 5     Fields:    Translation:HumansAnimals
    40. Aboshady I, Cody DD, Johnson EM, Gahremanpour A, Vela D, Khalil KG, Dupont HL, Willerson JT, Buja LM, Gladish GW. Flat-panel versus 64-channel computed tomography for in vivo quantitative characterization of aortic atherosclerotic plaques. Int J Cardiol. 2012 May 03; 156(3):295-302. PMID: 21185613; PMCID: PMC3074048.
      Citations:    Fields:    Translation:Animals
    41. Buja LM, Vela D, Buja LM. Immunologic and inflammatory reactions to exogenous stem cells implications for experimental studies and clinical trials for myocardial repair. J Am Coll Cardiol. 2010 Nov 16; 56(21):1693-700. PMID: 21070919.
      Citations:    
    42. Buja LM, Vela D. Current status of the role of stem cells in myocardial biology and repair. Cardiovasc Pathol. 2011 Sep-Oct; 20(5):297-301. PMID: 20846881.
      Citations:    
    43. Hitchcock KE, Caudell DN, Sutton JT, Klegerman ME, Vela D, Pyne-Geithman GJ, Abruzzo T, Cyr PE, Geng YJ, McPherson DD, Holland CK. Ultrasound-enhanced delivery of targeted echogenic liposomes in a novel ex vivo mouse aorta model. J Control Release. 2010 Jun 15; 144(3):288-95. PMID: 20202474; PMCID: PMC2878875.
      Citations:    
    44. Taegtmeyer H, Sen S, Vela D. Return to the fetal gene program: a suggested metabolic link to gene expression in the heart. Ann N Y Acad Sci. 2010 Feb; 1188:191-8. PMID: 20201903; PMCID: PMC3625436.
      Citations: 178     Fields:    Translation:HumansAnimals
    45. Kassiotis C, Ballal K, Wellnitz K, Vela D, Gong M, Salazar R, Frazier OH, Taegtmeyer H. Markers of autophagy are downregulated in failing human heart after mechanical unloading. Circulation. 2009 Sep 15; 120(11 Suppl):S191-7. PMID: 19752367; PMCID: PMC2778323.
      Citations: 69     Fields:    Translation:HumansCells
    46. Haidari M, Wyde PR, Litovsky S, Vela D, Ali M, Casscells SW, Madjid M. Influenza virus directly infects, inflames, and resides in the arteries of atherosclerotic and normal mice. Atherosclerosis. 2010 Jan; 208(1):90-6. PMID: 19665123.
      Citations:    
    47. Vela DC, Silva GV, Assad JA, Sousa AL, Coulter S, Fernandes MR, Perin EC, Willerson JT, Buja LM. Histopathological study of healing after allogenic mesenchymal stem cell delivery in myocardial infarction in dogs. J Histochem Cytochem. 2009 Feb; 57(2):167-76. PMID: 19001635; PMCID: PMC2628321.
      Citations: 20     Fields:    Translation:AnimalsCells
    48. Buja LM, Vela D. Cardiomyocyte death and renewal in the normal and diseased heart. Cardiovasc Pathol. 2008 Nov-Dec; 17(6):349-74. PMID: 18402842.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    49. Gertz SD, Bodmann BG, Vela D, Papadakis M, Aboshady I, Cherukuri P, Alexander S, Kouri DJ, Baid S, Gittens AA, Gladish GW, Conyers JL, Cody DD, Gavish L, Mazraeshahi RM, Wilner WT, Frazier L, Madjid M, Zarrabi A, Lukovenkov S, Ahmed A, Willerson JT, Casscells SW. Three-dimensional isotropic wavelets for post-acquisitional extraction of latent images of atherosclerotic plaque components from micro-computed tomography of human coronary arteries. Acad Radiol. 2007 Dec; 14(12):1509-19. PMID: 18035280.
      Citations: 1     Fields:    Translation:Humans
    50. Wilner WT, Mazraeshahi RM, Aboshady I, Bodmann BG, Papadakis M, Kouri D, Conyers JL, Cherukuri P, Vela D, Gladish G, Gavish L, Cody DD, Frazier L, Lukovenkov S, Madjid M, Zarrabi A, Ahmed A, Willerson JT, Casscells SW, Gertz SD. Quantification of roughness of calcific deposits in computed tomography scans of human coronary arteries. Invest Radiol. 2007 Nov; 42(11):771-6. PMID: 18030200.
      Citations: 1     Fields:    Translation:Humans
    51. Perin EC, Silva GV, Assad JA, Vela D, Buja LM, Sousa AL, Litovsky S, Lin J, Vaughn WK, Coulter S, Fernandes MR, Willerson JT. Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction. J Mol Cell Cardiol. 2008 Mar; 44(3):486-95. PMID: 18061611.
      Citations: 89     Fields:    Translation:AnimalsCells
    52. Vela D, Buja LM. Quest for the cardiovascular holy grail: mammalian myocardial regeneration. Cardiovasc Pathol. 2008 Jan-Feb; 17(1):1-5. PMID: 18160054.
      Citations:    
    53. Vela D, Buja LM, Madjid M, Burke A, Naghavi M, Willerson JT, Casscells SW, Litovsky S. The role of periadventitial fat in atherosclerosis. Arch Pathol Lab Med. 2007 Mar; 131(3):481-7. PMID: 17516753.
      Citations: 35     Fields:    Translation:HumansAnimals
    54. Madjid M, Vela D, Khalili-Tabrizi H, Casscells SW, Litovsky S. Systemic infections cause exaggerated local inflammation in atherosclerotic coronary arteries: clues to the triggering effect of acute infections on acute coronary syndromes. Tex Heart Inst J. 2007; 34(1):11-8. PMID: 17420787; PMCID: PMC1847934.
      Citations:    
    55. Gertz SD, Cherukuri P, Bodmann BG, Gladish G, Wilner WT, Conyers JL, Aboshady I, Madjid M, Vela D, Lukovenkov S, Papadakis M, Kouri D, Mazraeshahi RM, Frazier L, Zarrabi A, Elrod D, Willerson JT, Casscells SW. Usefulness of multidetector computed tomography for noninvasive evaluation of coronary arteries in asymptomatic patients. Am J Cardiol. 2006 Jan 15; 97(2):287-93. PMID: 16442381.
      Citations: 2     Fields:    Translation:Humans
    56. Silva GV, Litovsky S, Assad JA, Sousa AL, Martin BJ, Vela D, Coulter SC, Lin J, Ober J, Vaughn WK, Branco RV, Oliveira EM, He R, Geng YJ, Willerson JT, Perin EC. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation. 2005 Jan 18; 111(2):150-6. PMID: 15642764.
      Citations: 256     Fields:    Translation:AnimalsCells
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