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Chandra Bhushan B Mishra

TitlePostdoc Fellows and Associates
InstitutionBaylor College of Medicine
DepartmentPostDoc
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mishra CB, Shalini S, Gusain S, Kumar P, Kumari S, Choi YS, Kumari J, Moku BK, Yadav AK, Prakash A, Jeon R, Tiwari M. Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation. Biomed Pharmacother. 2024 Apr 01; 174:116484. PMID: 38565058.
      Citations:    Fields:    
    2. Ashraf-Uz-Zaman M, Chua TK, Li X, Yao Y, Moku BK, Mishra CB, Avadhanula V, Piedra PA, Song Y. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. ACS Infect Dis. 2024 Feb 09; 10(2):715-731. PMID: 38192109; PMCID: PMC10922772.
      Citations: 1     Fields:    Translation:HumansCells
    3. Li X, Wu X, Nie S, Zhao J, Yao Y, Wu F, Mishra CB, Ashraf-Uz-Zaman M, Moku BK, Song Y. Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L. Cancers (Basel). 2023 Nov 03; 15(21). PMID: 37958457; PMCID: PMC10650850.
      Citations:    
    4. Ashraf-Uz-Zaman M, Li X, Yao Y, Mishra CB, Moku BK, Song Y. Quinazolinone Compounds Have Potent Antiviral Activity against Zika and Dengue Virus. J Med Chem. 2023 08 10; 66(15):10746-10760. PMID: 37506506; PMCID: PMC10463567.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. Kumar N, Srivastava R, Mongre RK, Mishra CB, Kumar A, Khatoon R, Banerjee A, Ashraf-Uz-Zaman M, Singh H, Lynn AM, Lee MS, Prakash A. Identifying the Novel Inhibitors Against the Mycolic Acid Biosynthesis Pathway Target "mtFabH" of Mycobacterium tuberculosis. Front Microbiol. 2022; 13:818714. PMID: 35602011; PMCID: PMC9121832.
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    6. Mishra CB, Mongre RK, Prakash A, Jeon R, Supuran CT, Lee MS. Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in?vitro and in?vivo studies. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):954-963. PMID: 33947294; PMCID: PMC8118463.
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    7. Mongre RK, Mishra CB, Shukla AK, Prakash A, Jung S, Ashraf-Uz-Zaman M, Lee MS. Emerging Importance of Tyrosine Kinase Inhibitors against Cancer: Quo Vadis to Cure? Int J Mol Sci. 2021 Oct 28; 22(21). PMID: 34769090; PMCID: PMC8584061.
      Citations:    
    8. Mishra CB, Pandey P, Sharma RD, Malik MZ, Mongre RK, Lynn AM, Prasad R, Jeon R, Prakash A. Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach. Brief Bioinform. 2021 03 22; 22(2):1346-1360. PMID: 33386025; PMCID: PMC7799228.
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    9. Mishra CB, Kumari S, Angeli A, Bua S, Mongre RK, Tiwari M, Supuran CT. Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. J Med Chem. 2021 03 25; 64(6):3100-3114. PMID: 33721499.
      Citations:    
    10. Atale N, Mishra CB, Kohli S, Mongre RK, Prakash A, Kumari S, Yadav UCS, Jeon R, Rani V. Anti-inflammatory Effects of S. cumini Seed Extract on Gelatinase-B (MMP-9) Regulation against Hyperglycemic Cardiomyocyte Stress. Oxid Med Cell Longev. 2021; 2021:8839479. PMID: 33747350; PMCID: PMC7953863.
      Citations:    
    11. Mongre RK, Mishra CB, Jung S, Lee BS, Quynh NTN, Anh NH, Myagmarjav D, Jo T, Lee MS. Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis. Mol Ther Oncolytics. 2020 Dec 16; 19:105-126. PMID: 33102693; PMCID: PMC7554327.
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    12. Mishra CB, Gusain S, Shalini S, Kumari S, Prakash A, Kumari N, Yadav AK, Kumari J, Kumar K, Tiwari M. Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation. Bioorg Chem. 2020 01; 95:103524. PMID: 31918396.
      Citations:    
    13. Mongre RK, Mishra CB, Prakash A, Jung S, Lee BS, Kumari S, Hong JT, Lee MS. Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model. Cancers (Basel). 2019 Aug 25; 11(9). PMID: 31450709; PMCID: PMC6770606.
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    14. Mongre RK, Jung S, Mishra CB, Lee BS, Kumari S, Lee MS. Prognostic and Clinicopathological Significance of SERTAD1 in Various Types of Cancer Risk: A Systematic Review and Retrospective Analysis. Cancers (Basel). 2019 Mar 08; 11(3). PMID: 30857225; PMCID: PMC6469047.
      Citations:    
    15. Mishra CB, Kumari S, Angeli A, Bua S, Buonanno M, Monti SM, Tiwari M, Supuran CT. Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in?vitro and in?vivo appraisal. Eur J Med Chem. 2018 Aug 05; 156:430-443. PMID: 30015076.
      Citations:    
    16. Mishra CB, Kumari S, Siraj F, Yadav R, Kumari S, Tiwari AK, Tiwari M. The anti-epileptogenic and cognition enhancing effect of novel 1-[4-(4-benzo [1, 3] dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea (BPPU) in pentylenetetrazole induced chronic rat model of epilepsy. Biomed Pharmacother. 2018 Sep; 105:470-480. PMID: 29883942.
      Citations:    
    17. Mishra CB, Kumari S, Prakash A, Yadav R, Tiwari AK, Pandey P, Tiwari M. Discovery of novel Methylsulfonyl phenyl derivatives as potent human Cyclooxygenase-2 inhibitors with effective anticonvulsant action: Design, synthesis, in-silico, in-vitro and in-vivo evaluation. Eur J Med Chem. 2018 May 10; 151:520-532. PMID: 29655084.
      Citations:    
    18. Mishra CB, Kumari S, Angeli A, Bua S, Tiwari M, Supuran CT. Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. J Med Chem. 2018 04 12; 61(7):3151-3165. PMID: 29566486.
      Citations:    
    19. Mishra CB, Kumari S, Angeli A, Monti SM, Buonanno M, Tiwari M, Supuran CT. Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. J Med Chem. 2017 03 23; 60(6):2456-2469. PMID: 28253618.
      Citations:    
    20. Mishra CB, Mongre RK, Kumari S, Jeong DK, Tiwari M. Novel Triazole-Piperazine Hybrid Molecules Induce Apoptosis via Activation of the Mitochondrial Pathway and Exhibit Antitumor Efficacy in Osteosarcoma Xenograft Nude Mice Model. ACS Chem Biol. 2017 03 17; 12(3):753-768. PMID: 28084722.
      Citations:    
    21. Kumari S, Mishra CB, Idrees D, Prakash A, Yadav R, Hassan MI, Tiwari M. Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides. Mol Divers. 2017 Feb; 21(1):163-174. PMID: 28039637.
      Citations:    
    22. Mishra CB, Kumari S, Manral A, Prakash A, Saini V, Lynn AM, Tiwari M. Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease. Eur J Med Chem. 2017 Jan 05; 125:736-750. PMID: 27721157.
      Citations:    
    23. Mishra CB, Kumari S, Angeli A, Monti SM, Buonanno M, Prakash A, Tiwari M, Supuran CT. Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. J Enzyme Inhib Med Chem. 2016; 31(sup2):174-179. PMID: 27314170.
      Citations:    
    24. Mishra CB, Manral A, Kumari S, Saini V, Tiwari M. Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-?-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease. Bioorg Med Chem. 2016 08 15; 24(16):3829-41. PMID: 27353888.
      Citations:    
    25. Mishra CB, Kumari S, Tiwari M. Design and synthesis of some new 1-phenyl-3/4-[4-(aryl/heteroaryl/alkyl-piperazine1-yl)-phenyl-ureas as potent anticonvulsant and antidepressant agents. Arch Pharm Res. 2016 May; 39(5):603-17. PMID: 26891908.
      Citations:    
    26. Kumari S, Idrees D, Mishra CB, Prakash A, Ahmad F, Hassan MI, Tiwari M. Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea. J Mol Graph Model. 2016 Mar; 64:101-109. PMID: 26826799.
      Citations:    
    27. Kumari S, Mishra CB, Tiwari M. Polypharmacological Drugs in the Treatment of Epilepsy: The Comprehensive Review of Marketed and New Emerging Molecules. Curr Pharm Des. 2016; 22(21):3212-25. PMID: 26916017.
      Citations:    
    28. Kumari S, Mishra CB, Tiwari M. Pharmacological evaluation of novel 1-[4-(4-benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea as potent anticonvulsant and antidepressant agent. Pharmacol Rep. 2016 Apr; 68(2):250-8. PMID: 26922524.
      Citations:    
    29. Kumari S, Mishra CB, Tiwari M. Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents. Bioorg Med Chem Lett. 2015 Mar 01; 25(5):1092-9. PMID: 25619635.
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    30. Mishra CB, Kumari S, Tiwari M. Thiazole: a promising heterocycle for the development of potent CNS active agents. Eur J Med Chem. 2015 Mar 06; 92:1-34. PMID: 25544146.
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    31. Kumari N, Mishra CB, Prakash A, Kumar N, Mongre R, Luthra PM. 8-(Furan-2-yl)-3-phenethylthiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione as novel, selective and potent adenosine A(2A) receptor antagonist. Neurosci Lett. 2014 Jan 13; 558:203-7. PMID: 24161891.
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    32. Mishra CB, Sharma D, Prakash A, Kumari N, Kumar N, Luthra PM. Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists. Bioorg Med Chem. 2013 Oct 01; 21(19):6077-83. PMID: 23953686.
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    33. Barodia SK, Mishra CB, Prakash A, Senthil Kumar JB, Kumari N, Luthra PM. Novel 8-(furan-2-yl)-3-benzyl thiazolo [5,4-e][1,2,4] triazolo [1,5-c] pyrimidine-2(3H)-thione as selective adenosine A(2A) receptor antagonist. Neurosci Lett. 2011 Jan 13; 488(1):1-5. PMID: 20708066.
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    34. Mishra CB, Barodia SK, Prakash A, Senthil Kumar JB, Luthra PM. Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists. Bioorg Med Chem. 2010 Apr 01; 18(7):2491-500. PMID: 20303771.
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    35. Luthra PM, Prakash A, Barodia SK, Kumari R, Mishra CB, Kumar JB. In silico study of naphtha [1, 2-d] thiazol-2-amine with adenosine A 2A receptor and its role in antagonism of haloperidol-induced motor impairments in mice. Neurosci Lett. 2009 Oct 09; 463(3):215-8. PMID: 19654038.
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