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KRISHNA M. BOINI

TitleAssistant Professor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
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    Collapse Research 
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    R01DK104031     (BOINI, KRISHNA M)Mar 20, 2015 - Feb 29, 2020
    NIH/NIDDK
    Instigation of Glomerular Injury by Inflammasomes in Obesity: Beyond Inflammation
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhang L, Deng M, Lu A, Chen Y, Chen Y, Wu C, Tan Z, Boini KM, Yang T, Zhu Q, Wang L. Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism. J Cell Mol Med. 2019 Sep 29. PMID: 31565858.
      View in: PubMed
    2. Singh GB, Zhang Y, Boini KM, Koka S. High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction. Int J Mol Sci. 2019 Jul 22; 20(14). PMID: 31336567.
      View in: PubMed
    3. Koka S, Xia M, Zhang C, Zhang Y, Li PL, Boini KM. Podocyte NLRP3 Inflammasome Activation and Formation by Adipokine Visfatin. Cell Physiol Biochem. 2019; 53(2):355-365. PMID: 31385664.
      View in: PubMed
    4. Zhang P, Guan Y, Chen J, Li X, McConnell BK, Zhou W, Boini KM, Zhang Y. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis. 2018 11 19; 9(12):1145. PMID: 30451833.
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    5. Guan Y, Li X, Umetani M, Boini KM, Li PL, Zhang Y. Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells. Basic Clin Pharmacol Toxicol. 2019 Apr; 124(4):370-384. PMID: 30311396.
      View in: PubMed
    6. Lian D, Lai J, Wu Y, Wang L, Chen Y, Zhang Y, Boini KM, Huang Y, Chen Y. Cathepsin B-Mediated NLRP3 Inflammasome Formation and Activation in Angiotensin II -Induced Hypertensive Mice: Role of Macrophage Digestion Dysfunction. Cell Physiol Biochem. 2018; 50(4):1585-1600. PMID: 30359991.
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    7. Nalamolu KR, Chelluboina B, Magruder IB, Fru DN, Mohandass A, Venkatesh I, Klopfenstein JD, Pinson DM, Boini KM, Veeravalli KK. Post-stroke mRNA expression profile of MMPs: effect of genetic deletion of MMP-12. Stroke Vasc Neurol. 2018 Sep; 3(3):153-159. PMID: 30294471.
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    8. Hu J, Wang W, Zhang F, Li PL, Boini KM, Yi F, Li N. Hypoxia inducible factor-1a mediates the profibrotic effect of albumin in renal tubular cells. Sci Rep. 2017 Nov 20; 7(1):15878. PMID: 29158549.
      View in: PubMed
    9. Boini KM, Hussain T, Li PL, Koka S. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell Physiol Biochem. 2017; 44(1):152-162. PMID: 29130962.
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    10. Zhu Q, Hu J, Wang L, Wang W, Wang Z, Li PL, Boini KM, Li N. Inhibition of microRNA-429 in the renal medulla increased salt sensitivity of blood pressure in Sprague Dawley rats. J Hypertens. 2017 09; 35(9):1872-1880. PMID: 28445205.
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    11. Wang Z, Zhu Q, Wang W, Yi F, Li PL, Boini KM, Li N. Infusion of Valproic Acid Into the Renal Medulla Activates Stem Cell Population and Attenuates Salt-Sensitive Hypertension in Dahl S Rats. Cell Physiol Biochem. 2017; 42(3):1264-1273. PMID: 28693025.
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    12. Koka S, Xia M, Chen Y, Bhat OM, Yuan X, Boini KM, Li PL. Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia. Redox Biol. 2017 10; 13:336-344. PMID: 28633109.
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    13. Conley SM, Abais-Battad JM, Yuan X, Zhang Q, Boini KM, Li PL. Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia. Free Radic Biol Med. 2017 05; 106:236-244. PMID: 28193546.
      View in: PubMed
    14. Boini KM, Xia M, Koka S, Gehr TW, Li PL. Sphingolipids in obesity and related complications. Front Biosci (Landmark Ed). 2017 01 01; 22:96-116. PMID: 27814604.
      View in: PubMed
    15. Bao JX, Zhang QF, Wang M, Xia M, Boini KM, Gulbins E, Zhang Y, Li PL. Implication of CD38 gene in autophagic degradation of collagen I in mouse coronary arterial myocytes. Front Biosci (Landmark Ed). 2017 01 01; 22:558-569. PMID: 27814632.
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    16. Conley SM, Abais JM, Boini KM, Li PL. Inflammasome Activation in Chronic Glomerular Diseases. Curr Drug Targets. 2017; 18(9):1019-1029. PMID: 27538510.
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    17. Meng N, Xia M, Lu YQ, Wang M, Boini KM, Li PL, Tang WX. Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection. Oncotarget. 2016 Jun 28; 7(26):39316-39331. PMID: 27322427.
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    18. Ritter JK, Li G, Xia M, Boini K. Anandamide and its metabolites: what are their roles in the kidney? Front Biosci (Schol Ed). 2016 06 01; 8:264-77. PMID: 27100705.
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    19. Li G, Xia M, Abais JM, Boini K, Li PL, Ritter JK. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes. J Pharmacol Exp Ther. 2016 07; 358(1):61-70. PMID: 27189966.
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    20. Boini KM, Xia M, Koka S, Gehr TW, Li PL. Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene. Oncotarget. 2016 Apr 05; 7(14):19031-44. PMID: 26980705.
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    21. Xia M, Abais JM, Koka S, Meng N, Gehr TW, Boini KM, Li PL. Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice. Kidney Blood Press Res. 2016; 41(2):208-21. PMID: 27010539.
      View in: PubMed
    22. Li G, Li CX, Xia M, Ritter JK, Gehr TW, Boini K, Li PL. Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: role of p62/Sequestosome 1 as a signaling hub. Cell Physiol Biochem. 2015; 35(5):1773-86. PMID: 25832774.
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    23. Abais JM, Xia M, Zhang Y, Boini KM, Li PL. Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector? Antioxid Redox Signal. 2015 May 01; 22(13):1111-29. PMID: 25330206.
      View in: PubMed
    24. Chen Y, Li X, Boini KM, Pitzer AL, Gulbins E, Zhang Y, Li PL. Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis. Biochim Biophys Acta. 2015 Feb; 1853(2):396-408. PMID: 25450976.
      View in: PubMed
    25. Xia M, Conley SM, Li G, Li PL, Boini KM. Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion. Cell Physiol Biochem. 2014; 34(3):829-41. PMID: 25171193.
      View in: PubMed
    26. Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, Li PL. Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia. J Biol Chem. 2014 Sep 26; 289(39):27159-68. PMID: 25138219.
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    27. Xia M, Boini KM, Abais JM, Xu M, Zhang Y, Li PL. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am J Pathol. 2014 May; 184(5):1617-28. PMID: 24631027.
      View in: PubMed
    28. Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing. Biochim Biophys Acta. 2014 May; 1843(5):836-45. PMID: 24508291.
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    29. Li X, Zhang Y, Xia M, Gulbins E, Boini KM, Li PL. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. PLoS One. 2014; 9(1):e87552. PMID: 24475307.
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    30. Li X, Xu M, Pitzer AL, Xia M, Boini KM, Li PL, Zhang Y. Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis. J Mol Med (Berl). 2014 May; 92(5):473-85. PMID: 24463558.
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    31. Zhang Y, Xu M, Xia M, Li X, Boini KM, Wang M, Gulbins E, Ratz PH, Li PL. Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene. Cardiovasc Res. 2014 Apr 01; 102(1):68-78. PMID: 24445604.
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    32. Xiong J, Xia M, Xu M, Zhang Y, Abais JM, Li G, Riebling CR, Ritter JK, Boini KM, Li PL. Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes. J Cell Mol Med. 2013 Dec; 17(12):1598-607. PMID: 24238063.
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    33. Abais JM, Xia M, Li G, Gehr TW, Boini KM, Li PL. Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia. Free Radic Biol Med. 2014 Feb; 67:211-20. PMID: 24140862.
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    34. Wei YM, Li X, Xu M, Abais JM, Chen Y, Riebling CR, Boini KM, Li PL, Zhang Y. Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. Cell Physiol Biochem. 2013; 31(6):925-37. PMID: 23817226.
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    35. Li C, Xia M, Abais JM, Liu X, Li N, Boini KM, Li PL. Protective role of growth hormone against hyperhomocysteinemia-induced glomerular injury. Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun; 386(6):551-61. PMID: 23529346.
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    36. Wei YM, Li X, Xiong J, Abais JM, Xia M, Boini KM, Zhang Y, Li PL. Attenuation by statins of membrane raft-redox signaling in coronary arterial endothelium. J Pharmacol Exp Ther. 2013 May; 345(2):170-9. PMID: 23435541.
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    37. Xiong J, Xia M, Yi F, Abais JM, Li N, Boini KM, Li PL. Regulation of renin release via cyclic ADP-ribose-mediated signaling: evidence from mice lacking CD38 gene. Cell Physiol Biochem. 2013; 31(1):44-55. PMID: 23343681.
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    38. Xu M, Li X, Walsh SW, Zhang Y, Abais JM, Boini KM, Li PL. Intracellular two-phase Ca2+ release and apoptosis controlled by TRP-ML1 channel activity in coronary arterial myocytes. Am J Physiol Cell Physiol. 2013 Mar 01; 304(5):C458-66. PMID: 23283937.
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    39. Abais JM, Zhang C, Xia M, Liu Q, Gehr TW, Boini KM, Li PL. NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal. 2013 May 01; 18(13):1537-48. PMID: 23088210.
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    40. Li X, Han WQ, Boini KM, Xia M, Zhang Y, Li PL. TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl). 2013 Jan; 91(1):25-36. PMID: 23108456.
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    41. Boini KM, Xia M, Abais JM, Xu M, Li CX, Li PL. Acid sphingomyelinase gene knockout ameliorates hyperhomocysteinemic glomerular injury in mice lacking cystathionine-ß-synthase. PLoS One. 2012; 7(9):e45020. PMID: 23024785.
      View in: PubMed
    42. Boini KM, Xia M, Xiong J, Li C, Payne LP, Li PL. Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis. J Cell Mol Med. 2012 Aug; 16(8):1674-85. PMID: 21992601.
      View in: PubMed
    43. Zhang C, Boini KM, Xia M, Abais JM, Li X, Liu Q, Li PL. Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension. 2012 Jul; 60(1):154-62. PMID: 22647887.
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    44. Xu M, Xia M, Li XX, Han WQ, Boini KM, Zhang F, Zhang Y, Ritter JK, Li PL. Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells. Mol Biol Cell. 2012 Apr; 23(8):1546-57. PMID: 22357614.
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    45. Han WQ, Xia M, Xu M, Boini KM, Ritter JK, Li NJ, Li PL. Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells. J Cell Sci. 2012 Mar 01; 125(Pt 5):1225-34. PMID: 22349696.
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    46. Yao LJ, McCormick JA, Wang J, Yang KY, Kidwai A, Colussi GL, Boini KM, Birnbaum MJ, Lang F, German MS, Pearce D. Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null mice. Mol Endocrinol. 2011 Dec; 25(12):2106-18. PMID: 21980074.
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    47. Boini KM, Xia M, Li C, Zhang C, Payne LP, Abais JM, Poklis JL, Hylemon PB, Li PL. Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice. Am J Pathol. 2011 Nov; 179(5):2210-9. PMID: 21893018.
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    48. Ackermann TF, Boini KM, Beier N, Scholz W, Fuchss T, Lang F. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011; 28(1):137-46. PMID: 21865856.
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    49. Li CX, Xia M, Han WQ, Li XX, Zhang C, Boini KM, Liu XC, Li PL. Reversal by growth hormone of homocysteine-induced epithelial-to-mesenchymal transition through membrane raft-redox signaling in podocytes. Cell Physiol Biochem. 2011; 27(6):691-702. PMID: 21691087.
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    50. Zhang C, Xia M, Boini KM, Li CX, Abais JM, Li XX, Laperle LA, Li PL. Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemia. Pflugers Arch. 2011 Sep; 462(3):455-67. PMID: 21647593.
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    51. Föller M, Kempe DS, Boini KM, Pathare G, Siraskar B, Capuano P, Alesutan I, Sopjani M, Stange G, Mohebbi N, Bhandaru M, Ackermann TF, Judenhofer MS, Pichler BJ, Biber J, Wagner CA, Lang F. PKB/SGK-resistant GSK3 enhances phosphaturia and calciuria. J Am Soc Nephrol. 2011 May; 22(5):873-80. PMID: 21493770.
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    52. Fröhlich H, Boini KM, Seebohm G, Strutz-Seebohm N, Ureche ON, Föller M, Eichenmüller M, Shumilina E, Pathare G, Singh AK, Seidler U, Pfeifer KE, Lang F. Hypothyroidism of gene-targeted mice lacking Kcnq1. Pflugers Arch. 2011 Jan; 461(1):45-52. PMID: 20978783.
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    53. Zhang C, Yi F, Xia M, Boini KM, Zhu Q, Laperle LA, Abais JM, Brimson CA, Li PL. NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats. Antioxid Redox Signal. 2010 Oct 01; 13(7):975-86. PMID: 20406136.
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    54. Föller M, Bobbala D, Koka S, Boini KM, Mahmud H, Kasinathan RS, Shumilina E, Amann K, Beranek G, Sausbier U, Ruth P, Sausbier M, Lang F, Huber SM. Functional significance of the intermediate conductance Ca2+-activated K+ channel for the short-term survival of injured erythrocytes. Pflugers Arch. 2010 Nov; 460(6):1029-44. PMID: 20857305.
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    55. Boini KM, Zhang C, Xia M, Han WQ, Brimson C, Poklis JL, Li PL. Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells. Biochim Biophys Acta. 2010 Dec; 1801(12):1294-304. PMID: 20858552.
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    56. Xia M, Zhang C, Boini KM, Thacker AM, Li PL. Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res. 2011 Feb 01; 89(2):401-9. PMID: 20823276.
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    57. Fischer SS, Kempe DS, Leibrock CB, Rexhepaj R, Siraskar B, Boini KM, Ackermann TF, Föller M, Hocher B, Rosenblatt KP, Kuro-O M, Lang F. Hyperaldosteronism in Klotho-deficient mice. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F1171-7. PMID: 20719979.
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    58. Zemtsova IM, Heise N, Fröhlich H, Qadri SM, Kucherenko Y, Boini KM, Pearce D, Shumilina E, Lang F. Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3. Am J Physiol Cell Physiol. 2010 Nov; 299(5):C1007-14. PMID: 20686074.
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    59. Boini KM, Zhang C, Xia M, Poklis JL, Li PL. Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. J Pharmacol Exp Ther. 2010 Sep 01; 334(3):839-46. PMID: 20543095.
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    60. Huang DY, Gao H, Boini KM, Osswald H, Nürnberg B, Lang F. In vivo stimulation of AMP-activated protein kinase enhanced tubuloglomerular feedback but reduced tubular sodium transport during high dietary NaCl intake. Pflugers Arch. 2010 Jun; 460(1):187-96. PMID: 20349193.
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    61. Zhang C, Hu JJ, Xia M, Boini KM, Brimson CA, Laperle LA, Li PL. Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. Free Radic Biol Med. 2010 Apr 15; 48(8):1109-17. PMID: 20116427.
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    62. Zhang C, Hu JJ, Xia M, Boini KM, Brimson C, Li PL. Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytes. Biochim Biophys Acta. 2010 Apr; 1803(4):482-91. PMID: 20036696.
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    63. Rusai K, Wagner B, Roos M, Schmaderer C, Strobl M, Boini KM, Grenz A, Kuhl D, Heemann U, Lang F, Lutz J. The serum and glucocorticoid-regulated kinase 1 in hypoxic renal injury. Cell Physiol Biochem. 2009; 24(5-6):577-84. PMID: 19910698.
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    64. Nasir O, Wang K, Föller M, Gu S, Bhandaru M, Ackermann TF, Boini KM, Mack A, Klingel K, Amato R, Perrotti N, Kuhl D, Behrens J, Stournaras C, Lang F. Relative resistance of SGK1 knockout mice against chemical carcinogenesis. IUBMB Life. 2009 Jul; 61(7):768-76. PMID: 19548318.
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    65. Mauro TM, McCormick JA, Wang J, Boini KM, Ray L, Monks B, Birnbaum MJ, Lang F, Pearce D. Akt2 and SGK3 are both determinants of postnatal hair follicle development. FASEB J. 2009 Sep; 23(9):3193-202. PMID: 19433625.
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    66. Boini KM, Graf D, Hennige AM, Koka S, Kempe DS, Wang K, Ackermann TF, Föller M, Vallon V, Pfeifer K, Schleicher E, Ullrich S, Häring HU, Häussinger D, Lang F. Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1. Am J Physiol Regul Integr Comp Physiol. 2009 Jun; 296(6):R1695-701. PMID: 19369585.
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    67. Rotte A, Bhandaru M, Föller M, Biswas R, Mack AF, Friedrich B, Rexhepaj R, Nasir O, Ackermann TF, Boini KM, Kunzelmann K, Behrens J, Lang F. APC sensitive gastric acid secretion. Cell Physiol Biochem. 2009; 23(1-3):133-42. PMID: 19255508.
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    68. Koka S, Bobbala D, Lang C, Boini KM, Huber SM, Lang F. Influence of paclitaxel on parasitemia and survival of Plasmodium berghei infected mice. Cell Physiol Biochem. 2009; 23(1-3):191-8. PMID: 19255513.
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    69. Kempe DS, Ackermann TF, Fischer SS, Koka S, Boini KM, Mahmud H, Föller M, Rosenblatt KP, Kuro-O M, Lang F. Accelerated suicidal erythrocyte death in Klotho-deficient mice. Pflugers Arch. 2009 Jul; 458(3):503-12. PMID: 19184092.
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    70. Ackermann TF, Boini KM, Völkl H, Bhandaru M, Bareiss PM, Just L, Vallon V, Amann K, Kuhl D, Feng Y, Hammes HP, Lang F. SGK1-sensitive renal tubular glucose reabsorption in diabetes. Am J Physiol Renal Physiol. 2009 Apr; 296(4):F859-66. PMID: 19158347.
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    71. Rotte A, Bhandaru M, Ackermann TF, Boini KM, Lang F. Role of PDK1 in regulation of gastric acid secretion. Cell Physiol Biochem. 2008; 22(5-6):725-34. PMID: 19088454.
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    72. Boini KM, Amann K, Kempe D, Alessi DR, Lang F. Proteinuria in mice expressing PKB/SGK-resistant GSK3. Am J Physiol Renal Physiol. 2009 Jan; 296(1):F153-9. PMID: 18987114.
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    73. Bobbala D, Koka S, Lang C, Boini KM, Huber SM, Lang F. Effect of cyclosporine on parasitemia and survival of Plasmodium berghei infected mice. Biochem Biophys Res Commun. 2008 Nov 21; 376(3):494-8. PMID: 18789889.
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    74. Artunc F, Nasir O, Amann K, Boini KM, Häring HU, Risler T, Lang F. Serum- and glucocorticoid-inducible kinase 1 in doxorubicin-induced nephrotic syndrome. Am J Physiol Renal Physiol. 2008 Dec; 295(6):F1624-34. PMID: 18768591.
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    75. Boini KM, Nammi S, Grahammer F, Osswald H, Kuhl D, Lang F. Role of serum- and glucocorticoid-inducible kinase SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure. Kidney Blood Press Res. 2008; 31(4):280-9. PMID: 18753797.
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    76. Boini KM, Graf D, Kuhl D, Häussinger D, Lang F. SGK1 dependence of insulin induced hypokalemia. Pflugers Arch. 2009 Feb; 457(4):955-61. PMID: 18665390.
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    77. Koka S, Lang C, Boini KM, Bobbala D, Huber SM, Lang F. Influence of chlorpromazine on eryptosis, parasitemia and survival of Plasmodium berghe infected mice. Cell Physiol Biochem. 2008; 22(1-4):261-8. PMID: 18769053.
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    78. Koka S, Lang C, Niemoeller OM, Boini KM, Nicolay JP, Huber SM, Lang F. Influence of NO synthase inhibitor L-NAME on parasitemia and survival of Plasmodium berghei infected mice. Cell Physiol Biochem. 2008; 21(5-6):481-8. PMID: 18453756.
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    79. Boini KM, Bhandaru M, Mack A, Lang F. Steroid hormone release as well as renal water and electrolyte excretion of mice expressing PKB/SGK-resistant GSK3. Pflugers Arch. 2008 Sep; 456(6):1207-16. PMID: 18369660.
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    80. Rexhepaj R, Boini KM, Huang DY, Amann K, Artunc F, Wang K, Brosens JJ, Kuhl D, Lang F. Role of maternal glucocorticoid inducible kinase SGK1 in fetal programming of blood pressure in response to prenatal diet. Am J Physiol Regul Integr Comp Physiol. 2008 Jun; 294(6):R2008-13. PMID: 18367651.
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    81. Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol. 2008 May; 28(10):3258-72. PMID: 18347057.
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    82. Nasir O, Artunc F, Saeed A, Kambal MA, Kalbacher H, Sandulache D, Boini KM, Jahovic N, Lang F. Effects of gum arabic (Acacia senegal) on water and electrolyte balance in healthy mice. J Ren Nutr. 2008 Mar; 18(2):230-8. PMID: 18267216.
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    83. Artunc F, Sandulache D, Nasir O, Boini KM, Friedrich B, Beier N, Dicks E, Pötzsch S, Klingel K, Amann K, Blazer-Yost BL, Scholz W, Risler T, Kuhl D, Lang F. Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARgamma agonist pioglitazone. Pflugers Arch. 2008 May; 456(2):425-36. PMID: 18172605.
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    84. Koka S, Huber SM, Boini KM, Lang C, Föller M, Lang F. Lead decreases parasitemia and enhances survival of Plasmodium berghei-infected mice. Biochem Biophys Res Commun. 2007 Nov 23; 363(3):484-9. PMID: 17888870.
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    85. Feroze-Zaidi F, Fusi L, Takano M, Higham J, Salker MS, Goto T, Edassery S, Klingel K, Boini KM, Palmada M, Kamps R, Groothuis PG, Lam EW, Smith SK, Lang F, Sharkey AM, Brosens JJ. Role and regulation of the serum- and glucocorticoid-regulated kinase 1 in fertile and infertile human endometrium. Endocrinology. 2007 Oct; 148(10):5020-9. PMID: 17640988.
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    86. Sandu C, Artunc F, Grahammer F, Rotte A, Boini KM, Friedrich B, Sandulache D, Metzger M, Just L, Mack A, Skutella T, Rexhepaj R, Risler T, Wulff P, Kuhl D, Lang F. Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion. Pflugers Arch. 2007 Dec; 455(3):493-503. PMID: 17618452.
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    87. Koka S, Föller M, Lamprecht G, Boini KM, Lang C, Huber SM, Lang F. Iron deficiency influences the course of malaria in Plasmodium berghei infected mice. Biochem Biophys Res Commun. 2007 Jun 08; 357(3):608-14. PMID: 17445762.
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    88. Huang DY, Boini KM, Osswald H, Friedrich B, Artunc F, Ullrich S, Rajamanickam J, Palmada M, Wulff P, Kuhl D, Vallon V, Lang F. Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet. Am J Physiol Renal Physiol. 2006 Dec; 291(6):F1264-73. PMID: 17003223.
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    90. Huang DY, Boini KM, Friedrich B, Metzger M, Just L, Osswald H, Wulff P, Kuhl D, Vallon V, Lang F. Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Am J Physiol Regul Integr Comp Physiol. 2006 Apr; 290(4):R935-44. PMID: 16284089.
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    91. Huang DY, Boini KM, Lang PA, Grahammer F, Duszenko M, Heller-Stilb B, Warskulat U, Häussinger D, Lang F, Vallon V. Impaired ability to increase water excretion in mice lacking the taurine transporter gene TAUT. Pflugers Arch. 2006 Feb; 451(5):668-77. PMID: 16249932.
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    92. Nammi S, Boini KM, Koppula S, Sreemantula S. Reserpine-induced central effects: pharmacological evidence for the lack of central effects of reserpine methiodide. Can J Physiol Pharmacol. 2005 Jun; 83(6):509-15. PMID: 16049551.
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    93. Sreemantula S, Nammi S, Kolanukonda R, Koppula S, Boini KM. Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model. BMC Complement Altern Med. 2005 Jan 19; 5:1. PMID: 15656916.
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    94. Sreemantula S, Boini KM, Nammi S. Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion of VMA and 5-HIAA without affecting HVA in rats. BMC Pharmacol. 2004 Nov 16; 4:30. PMID: 15546495.
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    95. Nammi S, Koka S, Chinnala KM, Boini KM. Obesity: an overview on its current perspectives and treatment options. Nutr J. 2004 Apr 14; 3:3. PMID: 15084221.
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    96. Nammi S, Gudavalli R, Babu BS, Lodagala DS, Boini KM. Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs. BMC Complement Altern Med. 2003 Oct 16; 3:5. PMID: 14561229.
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