Receptor, Metabotropic Glutamate 5
"Receptor, Metabotropic Glutamate 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I G protein-coupled receptor mostly expressed post-synaptic pyramidal cells of the cortex and CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D064529
|
| MeSH Number(s) |
D12.776.543.750.695.450.500 D12.776.543.750.720.200.450.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Metabotropic Glutamate 5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.695.450.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glutamate [D12.776.543.750.720.200.450]
- Receptors, Metabotropic Glutamate [D12.776.543.750.720.200.450.500]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.720.200.450.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Metabotropic Glutamate 5".
This graph shows the total number of publications written about "Receptor, Metabotropic Glutamate 5" by people in this website by year, and whether "Receptor, Metabotropic Glutamate 5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Metabotropic Glutamate 5" by people in Profiles.
-
mGluR5 from Primary Sensory Neurons Promotes Opioid-Induced Hyperalgesia and Tolerance by Interacting with and Potentiating Synaptic NMDA Receptors. J Neurosci. 2023 08 02; 43(31):5593-5607.
-
mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity. Psychopharmacology (Berl). 2020 Feb; 237(2):345-361.
-
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression. Mol Psychiatry. 2018 04; 23(4):824-832.
-
Estradiol Facilitation of Cocaine Self-Administration in Female Rats Requires Activation of mGluR5. eNeuro. 2016 Sep-Oct; 3(5).
-
mGluR5 Exerts Cell-Autonomous Influences on the Functional and Anatomical Development of Layer IV Cortical Neurons in the Mouse Primary Somatosensory Cortex. J Neurosci. 2016 08 24; 36(34):8802-14.
-
In vivo ketamine-induced changes in [??C]ABP688 binding to metabotropic glutamate receptor subtype 5. Biol Psychiatry. 2015 Feb 01; 77(3):266-275.
-
Stress hormone exposure reduces mGluR5 expression in the nucleus accumbens: functional implications for interoceptive sensitivity to alcohol. Neuropsychopharmacology. 2014 Sep; 39(10):2376-86.
-
mGluR5 Upregulation increases excitability of hypothalamic presympathetic neurons through NMDA receptor trafficking in spontaneously hypertensive rats. J Neurosci. 2014 Mar 19; 34(12):4309-17.
-
mGluR5 ablation in cortical glutamatergic neurons increases novelty-induced locomotion. PLoS One. 2013; 8(8):e70415.
-
Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception. Mol Pain. 2012 Mar 26; 8:20.