Immunoglobulin Light-chain Amyloidosis

"Immunoglobulin Light-chain Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.

Descriptor ID	D000075363
MeSH Number(s)	C04.557.595.250 C18.452.845.500.550 C20.683.515.507 C20.683.780.565
Concept/Terms	Immunoglobulin Light-chain Amyloidosis Immunoglobulin Light-chain Amyloidosis Immunoglobulin Light chain Amyloidosis Immunoglobulin Light-chain Amyloidoses Amyloidosis, Primary AL Amyloidosis AL Amyloidoses Primary Systemic Amyloidosis Amyloidoses, Primary Systemic Amyloidosis, Primary Systemic Primary Systemic Amyloidoses Systemic Amyloidoses, Primary Systemic Amyloidosis, Primary Amyloidosis, Immunoglobulin Light-chain Amyloidosis, Immunoglobulin Light chain Primary Amyloidosis Amyloidoses, Primary Primary Amyloidoses

Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light-chain Amyloidosis".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Plasma Cell [C04.557.595]
Immunoglobulin Light-chain Amyloidosis [C04.557.595.250]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Proteostasis Deficiencies [C18.452.845]
Amyloidosis [C18.452.845.500]
Immunoglobulin Light-chain Amyloidosis [C18.452.845.500.550]
Immune System Diseases [C20]
Immunoproliferative Disorders [C20.683]
Lymphoproliferative Disorders [C20.683.515]
Immunoglobulin Light-chain Amyloidosis [C20.683.515.507]
Paraproteinemias [C20.683.780]
Immunoglobulin Light-chain Amyloidosis [C20.683.780.565]

Below are MeSH descriptors whose meaning is related to "Immunoglobulin Light-chain Amyloidosis".

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light-chain Amyloidosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunoglobulin Light-chain Amyloidosis" by people in this website by year, and whether "Immunoglobulin Light-chain Amyloidosis" was a major or minor topic of these publications.

Bar chart showing 14 publications over 9 distinct years, with a maximum of 2 publications in 2013 and 2017 and 2018 and 2019 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	1	1
2013	0	2	2
2015	0	1	1
2016	0	1	1
2017	1	1	2
2018	2	0	2
2019	2	0	2
2020	2	0	2
2021	1	0	1

Below are the most recent publications written about "Immunoglobulin Light-chain Amyloidosis" by people in Profiles.

Tan CR, Estrada-Merly N, Landau H, Lekakis L, Banerjee R, Mian H, Usmani SZ, Hanbali A, Lazarus HM, Kyle RA, Dholaria B, Bal S, Strouse C, Murthy HS, Wirk B, Nishihori T, Kumar S, Shah N, Qazilbash M, D'Souza A. A second autologous hematopoietic cell transplantation is a safe and effective salvage therapy in select relapsed or refractory AL amyloidosis patients. Bone Marrow Transplant. 2022 Feb; 57(2):295-298.

View in: PubMed
Heybeli C, Bentall A, Wen J, Alexander MP, Buadi FK, Cosio FG, Dean PG, Dispenzieri A, Dingli D, El Ters M, Gertz MA, Hatem A, Kapoor P, Khamash H, Kourelis T, Kumar S, Lorenz EC, Mai M, Muchtar E, Murray DL, Prieto M, Schinstock CA, Stegall MD, Warsame R, Leung N. A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis. Kidney Int. 2021 03; 99(3):707-715.

View in: PubMed
Chen EC, Rubinstein S, Soto C, Bombardi RG, Day SB, Myers L, Zaytsev A, Majedi M, Cornell RF, Crowe JE. Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713.

View in: PubMed
Patil N, Arora S, Qamar A, Strassle PD, Alexander KM, Fatima A, Maurer MS, Grodin JL, Pandey A. Trends and causes of hospitalizations in patients with amyloidosis. Amyloid. 2019 Sep; 26(3):177-178.

View in: PubMed
Chan TM, Prospero Ponce CM, Allen RC, Bell D, Lee AG. Orbital AL amyloid. Orbit. 2020 Feb; 39(1):68-70.

View in: PubMed
Boyle EM, Ashby C, Wardell CP, Rowczenio D, Sachchithanantham S, Wang Y, Johnson SK, Bauer MA, Weinhold N, Kaiser MF, Johnson DC, Jones JR, Pawlyn C, Proszek P, Schinke C, Facon T, Dumontet C, Davies FE, Morgan GJ, Walker BA, Wechalekar AD. The genomic landscape of plasma cells in systemic light chain amyloidosis. Blood. 2018 12 27; 132(26):2775-2777.

View in: PubMed
Afrough A, Saliba RM, Hamdi A, Honhar M, Varma A, Cornelison AM, Rondon G, Parmar S, Shah ND, Bashir Q, Hosing C, Popat U, Weber DM, Thomas S, Orlowski RZ, Champlin RE, Qazilbash MH. Impact of Induction Therapy on the Outcome of Immunoglobulin Light Chain Amyloidosis after Autologous Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2018 11; 24(11):2197-2203.

View in: PubMed
Yeh JC, Shank BR, Milton DR, Qazilbash MH. Adverse Prognostic Factors for Morbidity and Mortality During Peripheral Blood Stem Cell Mobilization in Patients with Light Chain Amyloidosis. Biol Blood Marrow Transplant. 2018 04; 24(4):815-819.

View in: PubMed
Lee MY, Byun JY, Choi YW, Choi HY. Multiple myeloma presenting with acquired cutis laxa and primary systemic amyloidosis. Eur J Dermatol. 2017 12 01; 27(6):654-655.

View in: PubMed
Thakral B, Kanagal-Shamanna R. Systemic AL amyloidosis associated with Waldenström macroglobulinemia: an unusual presenting complication. Blood. 2016 Jan 07; 127(1):168.

View in: PubMed

People

Explore

Similar Concepts

Top Journals