Regulatory Factor X Transcription Factors
"Regulatory Factor X Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.
| Descriptor ID |
D000071701
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| MeSH Number(s) |
D12.776.260.950.624 D12.776.930.977.624
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Regulatory Factor X Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Regulatory Factor X Transcription Factors".
This graph shows the total number of publications written about "Regulatory Factor X Transcription Factors" by people in this website by year, and whether "Regulatory Factor X Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Regulatory Factor X Transcription Factors" by people in Profiles.
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Mitchell-Riley Syndrome: Improving Clinical Outcomes and Searching for Functional Impact of RFX-6 Mutations. Front Endocrinol (Lausanne). 2022; 13:802351.
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Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior. Genet Med. 2021 06; 23(6):1028-1040.
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Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4a (HNF4?) Is Vital to Beta-cell Function. J Biol Chem. 2016 Mar 18; 291(12):6146-57.
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Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metab. 2014 Sep 02; 20(3):471-82.
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XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway. Nature. 2014 Apr 03; 508(7494):103-107.
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Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem. 2012 Jun 01; 287(23):19687-98.
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Activation of unfolded protein response in transgenic mouse lenses. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2100-8.
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Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells. Physiol Genomics. 2011 Feb 11; 43(3):174-86.
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XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 2010 Dec; 139(6):2038-49.
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Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia. J Cell Mol Med. 2010 Jun; 14(6B):1509-19.