AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase
"AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. It can also repair alkylated DNA containing 1-ethenoadenine in vitro. It has highest affinity for double-stranded DNA.
| Descriptor ID |
D000071499
|
| MeSH Number(s) |
D08.811.074.062.750 D08.811.682.690.416.139.750
|
| Concept/Terms |
AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase- AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase
- AlkB Homolog 2, Alpha Ketoglutarate Dependent Dioxygenase
- Alkylated DNA Repair Protein AlkB Homolog 2
- Oxy DC1 Protein
- DNA Oxidative Demethylase ALKBH2
- Alpha-ketoglutarate-Dependent Dioxygenase AlkB Homolog 2
- Alpha ketoglutarate Dependent Dioxygenase AlkB Homolog 2
|
Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase".
This graph shows the total number of publications written about "AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase" by people in this website by year, and whether "AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase" was a major or minor topic of these publications.
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Below are the most recent publications written about "AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase" by people in Profiles.
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Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Rep. 2015 Dec 22; 13(11):2353-2361.