Chitinase-3-Like Protein 1
"Chitinase-3-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
Descriptor ID |
D000071451
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MeSH Number(s) |
D08.811.277.450.207.500 D12.776.503.070
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Concept/Terms |
Chitinase-3-Like Protein 1- Chitinase-3-Like Protein 1
- Chitinase 3 Like Protein 1
- Cartilage Glycoprotein 39
- Glycoprotein 39, Cartilage
- GP-39 Protein
- GP 39 Protein
- YLK-40 Protein
- YLK 40 Protein
- CHI3L1 Protein
- CGP-39 Protein
- CGP 39 Protein
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Below are MeSH descriptors whose meaning is more general than "Chitinase-3-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Chitinase-3-Like Protein 1".
This graph shows the total number of publications written about "Chitinase-3-Like Protein 1" by people in this website by year, and whether "Chitinase-3-Like Protein 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 2 | 2 |
2006 | 0 | 1 | 1 |
2007 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chitinase-3-Like Protein 1" by people in Profiles.
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Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. Elife. 2021 06 10; 10.
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Serum biomarkers and transient elastography as predictors of advanced liver fibrosis in a United States cohort: the Boston children's hospital experience. J Pediatr. 2013 Oct; 163(4):1058-64.e2.
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REST regulates oncogenic properties of glioblastoma stem cells. Stem Cells. 2012 Mar; 30(3):405-14.
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Selective repression of YKL-40 by NF-kappaB in glioma cell lines involves recruitment of histone deacetylase-1 and -2. FEBS Lett. 2008 Sep 22; 582(21-22):3193-200.
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Exoskeletons and exhalation. N Engl J Med. 2007 Nov 15; 357(20):2082-4.
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Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol. 2007 Jun 01; 25(16):2288-94.
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Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res. 2006 Jul 01; 12(13):3935-41.
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YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma. Clin Cancer Res. 2005 May 01; 11(9):3326-34.
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Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005 Mar 01; 65(5):1678-86.