"Galectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.
| Descriptor ID |
D037161
|
| MeSH Number(s) |
D12.776.503.307
|
| Concept/Terms |
Galectins- Galectins
- beta-Galactoside Binding Lectin
- Binding Lectin, beta-Galactoside
- Lectin, beta-Galactoside Binding
- beta Galactoside Binding Lectin
- D-Galactoside-Binding Lectin
- D Galactoside Binding Lectin
- Lectin, D-Galactoside-Binding
- S-Type Lectins
- S Type Lectins
- Galaptins
- Galectin
- Lectins, S-Type
- Lectins, S Type
- S-Type Lectin
- Lectin, S-Type
- S Type Lectin
- beta-D-Galactosyl-Specific Lectin
- Lectin, beta-D-Galactosyl-Specific
- beta D Galactosyl Specific Lectin
- Galactose-Binding Lectin
- Galactose Binding Lectin
- Lectin, Galactose-Binding
|
Below are MeSH descriptors whose meaning is more general than "Galectins".
Below are MeSH descriptors whose meaning is more specific than "Galectins".
This graph shows the total number of publications written about "Galectins" by people in this website by year, and whether "Galectins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 3 | 4 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 2 | 3 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Galectins" by people in Profiles.
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Genetic Deletion of Galectin-3 Inhibits Pancreatic Cancer Progression and Enhances the Efficacy of Immunotherapy. Gastroenterology. 2024 Jul; 167(2):298-314.
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Inhibition of Galectin-9 sensitizes tumors to anthracycline treatment via inducing antitumor immunity. Int J Biol Sci. 2023; 19(14):4644-4656.
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Galectin-9 blockade synergizes with ATM inhibition to induce potent anti-tumor immunity. Int J Biol Sci. 2023; 19(3):981-993.
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Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography. Commun Biol. 2022 05 05; 5(1):419.
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Obesity, Galectin-3, and Incident Heart Failure: The ARIC Study. J Am Heart Assoc. 2022 05 03; 11(9):e023238.
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Development and characterization of anti-galectin-9 antibodies that protect T cells from galectin-9-induced cell death. J Biol Chem. 2022 04; 298(4):101821.
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A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice. Cell Rep Med. 2021 08 17; 2(8):100372.
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Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy. Nat Commun. 2021 02 05; 12(1):832.
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Fibrosis and Inflammatory Markers and Long-Term Risk of Peripheral Artery Disease: The ARIC Study. Arterioscler Thromb Vasc Biol. 2020 09; 40(9):2322-2331.
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Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study. J Am Heart Assoc. 2020 07 07; 9(13):e015405.