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PERUMAL THIAGARAJAN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
DivisionPathology
AddressDepartment of Pathology
One Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Thrombosis Research


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhou Y, Cai W, Zhao Z, Hilton T, Wang M, Yeon J, Liu W, Zhang F, Shi FD, Wu X, Thiagarajan P, Li M, Zhang J, Dong JF. Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice. Blood. 2018 Feb 01; 131(5):563-572. PMID: 29162596.
      View in: PubMed
    2. Dasgupta SK, Le A, Vijayan KV, Thiagarajan P. Dasatinib inhibits actin fiber reorganization and promotes endothelial cell permeability through RhoA-ROCK pathway. Cancer Med. 2017 Mar 18. PMID: 28316141.
      View in: PubMed
    3. Chang E, Rivero G, Jiang B, Yellapragada S, Thiagarajan P. Gelatinous Marrow Transformation Associated with Imatinib: Case Report and Literature Review. Case Rep Hematol. 2017; 2017:1950724. PMID: 28133556.
      View in: PubMed
    4. Dasgupta SK, Le A, Da Q, Cruz M, Rumbaut RE, Thiagarajan P. Wdr1-Dependent Actin Reorganization in Platelet Activation. PLoS One. 2016; 11(9):e0162897. PMID: 27627652.
      View in: PubMed
    5. Hu Q, Cho MS, Thiagarajan P, Aung FM, Sood AK, Afshar-Kharghan V. A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets. Platelets. 2016 Aug 18; 1-4. PMID: 27534811.
      View in: PubMed
    6. Hu Q, Wang M, Cho MS, Wang C, Nick AM, Thiagarajan P, Aung FM, Han X, Sood AK, Afshar-Kharghan V. Lipid profile of platelets and platelet-derived microparticles in ovarian cancer. BBA Clin. 2016 Dec; 6:76-81. PMID: 27453821; PMCID: PMC4941562.
    7. Zhao Z, Wang M, Tian Y, Hilton T, Salsbery B, Zhou EZ, Wu X, Thiagarajan P, Boilard E, Li M, Zhang J, Dong JF. Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury-associated coagulopathy in mice. Blood. 2016 Jun 2; 127(22):2763-72. PMID: 27002118; PMCID: PMC4891956 [Available on 06/02/17].
    8. Agarwaal A, Green L, Thiagarajan P. Gouty tophi in the bone marrow. Br J Haematol. 2016 Jan; 172(1):9. PMID: 26343541.
      View in: PubMed
    9. Song J, Yoon D, Christensen RD, Horvathova M, Thiagarajan P, Prchal JT. HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis. J Mol Med (Berl). 2015 Aug; 93(8):857-66. PMID: 26017143.
      View in: PubMed
    10. Thiagarajan P. HLA class II meets ?2-glycoprotein I. Blood. 2015 Apr 30; 125(18):2741. PMID: 25931579.
      View in: PubMed
    11. Nguyen TC, Gushiken F, Correa JI, Dong JF, Dasgupta SK, Thiagarajan P, Cruz MA. A recombinant fragment of von Willebrand factor reduces fibrin-rich microthrombi formation in mice with endotoxemia. Thromb Res. 2015 May; 135(5):1025-30. PMID: 25769494.
      View in: PubMed
    12. Uy N, Thiagarajan P, Musher DM. Cephalosporin side chain idiosyncrasies: a case report of ceftriaxone-induced agranulocytosis and review of literature. Open Forum Infect Dis. 2015 Jan; 2(1):ofv007. PMID: 26034758.
      View in: PubMed
    13. Tian Y, Salsbery B, Wang M, Yuan H, Yang J, Zhao Z, Wu X, Zhang Y, Konkle BA, Thiagarajan P, Li M, Zhang J, Dong JF. Brain-derived microparticles induce systemic coagulation in a murine model of traumatic brain injury. Blood. 2015 Mar 26; 125(13):2151-9. PMID: 25628471; PMCID: PMC4375111.
    14. Nautiyal K, Li R, Yellapragada S, Thiagarajan P, Mims M, Rivero G. Progressive transfusion and growth factor independence with adjuvant sertraline in low risk myelodysplastic syndrome treated with an erythropoiesis stimulating agent and granulocyte-colony stimulating factor. Leuk Res Rep. 2015; 4(1):1-3. PMID: 25709889; PMCID: PMC4327762.
    15. Dasgupta SK, Le A, Haudek SB, Entman ML, Rumbaut RE, Thiagarajan P. Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets. PLoS One. 2013; 8(12):e84649. PMID: 24358370; PMCID: PMC3865301.
    16. Pongas G, Dasgupta SK, Thiagarajan P. Antiplatelet factor 4/heparin antibodies in patients with gram negative bacteremia. Thromb Res. 2013 Aug; 132(2):217-20. PMID: 23830968.
      View in: PubMed
    17. Thiagarajan P, Afshar-Kharghan V. Platelet transfusion therapy. Hematol Oncol Clin North Am. 2013 Jun; 27(3):629-43. PMID: 23714315.
      View in: PubMed
    18. Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. Prostate. 2013 Feb 15; 73(3):267-77. PMID: 22821817; PMCID: PMC3961010.
    19. Dasgupta SK, Le A, Chavakis T, Rumbaut RE, Thiagarajan P. Developmental endothelial locus-1 (Del-1) mediates clearance of platelet microparticles by the endothelium. Circulation. 2012 Apr 3; 125(13):1664-72. PMID: 22388320.
      View in: PubMed
    20. Zhou Z, Thiagarajan P, Udden M, Lòpez JA, Guchhait P. Erythrocyte membrane sulfatide plays a crucial role in the adhesion of sickle erythrocytes to endothelium. Thromb Haemost. 2011 Jun; 105(6):1046-52. PMID: 21437360.
      View in: PubMed
    21. Dasgupta SK, Argaiz ER, Mercado JE, Maul HO, Garza J, Enriquez AB, Abdel-Monem H, Prakasam A, Andreeff M, Thiagarajan P. Platelet senescence and phosphatidylserine exposure. Transfusion. 2010 Oct; 50(10):2167-75. PMID: 20456701; PMCID: PMC2921562.
    22. Mandava P, Dalmeida W, Anderson JA, Thiagarajan P, Fabian RH, Weir RU, Kent TA. A Pilot Trial of Low-Dose Intravenous Abciximab and Unfractionated Heparin for Acute Ischemic Stroke: Translating GP IIb/IIIa Receptor Inhibition to Clinical Practice. Transl Stroke Res. 2010 Sep; 1(3):170-7. PMID: 24323522.
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    23. Abdel-Monem H, Dasgupta SK, Le A, Prakasam A, Thiagarajan P. Phagocytosis of platelet microvesicles and beta2- glycoprotein I. Thromb Haemost. 2010 Aug; 104(2):335-41. PMID: 20539917.
      View in: PubMed
    24. Abdel-Monem H, Prakasam A, Thiagarajan P. Howell-jolly body-like inclusions in neutrophils of a transplant recipient in association with ganciclovir therapy. Arch Pathol Lab Med. 2010 Jun; 134(6):809-10. PMID: 20524856.
      View in: PubMed
    25. Dasgupta SK, Abdel-Monem H, Niravath P, Le A, Bellera RV, Langlois K, Nagata S, Rumbaut RE, Thiagarajan P. Lactadherin and clearance of platelet-derived microvesicles. Blood. 2009 Feb 5; 113(6):1332-9. PMID: 19023116; PMCID: PMC2637196.
    26. Dasgupta SK, Abdel-Monem H, Guchhait P, Nagata S, Thiagarajan P. Role of lactadherin in the clearance of phosphatidylserine-expressing red blood cells. Transfusion. 2008 Nov; 48(11):2370-6. PMID: 18647368.
      View in: PubMed
    27. Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, Wang J. Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008 Jul 10; 454(7201):232-5. PMID: 18454133; PMCID: PMC2570948.
    28. Guchhait P, Shrimpton CN, Honke K, Rumbaut RE, Lopez JA, Thiagarajan P. Effect of an anti-sulfatide single-chain antibody probe on platelet function. Thromb Haemost. 2008 Mar; 99(3):552-7. PMID: 18327404.
      View in: PubMed
    29. Mandava P, Thiagarajan P, Kent TA. Glycoprotein IIb/IIIa antagonists in acute ischaemic stroke: current status and future directions. Drugs. 2008; 68(8):1019-28. PMID: 18484795.
      View in: PubMed
    30. Guchhait P, Dasgupta SK, Le A, Yellapragada S, López JA, Thiagarajan P. Lactadherin mediates sickle cell adhesion to vascular endothelial cells in flowing blood. Haematologica. 2007 Sep; 92(9):1266-7. PMID: 17768123.
      View in: PubMed
    31. Dasgupta SK, Thiagarajan P. Inhibition of thrombin activity by prothrombin activation fragment 1.2. J Thromb Thrombolysis. 2007 Oct; 24(2):157-62. PMID: 17334934.
      View in: PubMed
    32. Jaber A, Nong M, Thiagarajan P. Transient neutrophilic thrombophagocytosis associated with Citrobacter freundii septicemia. Arch Pathol Lab Med. 2006 Dec; 130(12):1754-5. PMID: 17149945.
      View in: PubMed
    33. Dasgupta SK, Guchhait P, Thiagarajan P. Lactadherin binding and phosphatidylserine expression on cell surface-comparison with annexin A5. Transl Res. 2006 Jul; 148(1):19-25. PMID: 16887494.
      View in: PubMed
    34. Afshar-Kharghan V, Thiagarajan P. Leukocyte adhesion and thrombosis. Curr Opin Hematol. 2006 Jan; 13(1):34-9. PMID: 16319685.
      View in: PubMed
    35. Dasgupta SK, Thiagarajan P. The role of lactadherin in the phagocytosis of phosphatidylserine-expressing sickle red blood cells by macrophages. Haematologica. 2005 Sep; 90(9):1267-8. PMID: 16154850.
      View in: PubMed
    36. Wadia Y, Thiagarajan P, Delgado R, Allison P, Robertson K, Frazier OH. Antiphospholipid syndrome with anti-prothrombin autoantibodies in a patient with an axial-flow left ventricular assist device. J Heart Lung Transplant. 2005 Aug; 24(8):1133-6. PMID: 16102458.
      View in: PubMed
    37. Del Conde I, Shrimpton CN, Thiagarajan P, López JA. Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood. 2005 Sep 1; 106(5):1604-11. PMID: 15741221.
      View in: PubMed
    38. del Conde I, Nabi F, Tonda R, Thiagarajan P, López JA, Kleiman NS. Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):1065-70. PMID: 15705928.
      View in: PubMed
    39. Krishnan B, Thiagarajan P. Images in hematology. Myeloma with Russell bodies. Am J Hematol. 2005 Jan; 78(1):79. PMID: 15609291.
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    40. Merten M, Beythien C, Gutensohn K, Kühnl P, Meinertz T, Thiagarajan P. Sulfatides activate platelets through P-selectin and enhance platelet and platelet-leukocyte aggregation. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):258-63. PMID: 15528476.
      View in: PubMed
    41. Guchhait P, López JA, Thiagarajan P. Characterization of autoantibodies against sulfatide from a V-gene phage-display library derived from patients with systemic lupus erythematosus. J Immunol Methods. 2004 Dec; 295(1-2):129-37. PMID: 15627618.
      View in: PubMed
    42. Le A, Dasgupta S, Planque S, Paul S, Thiagarajan P. Lupus-derived antiprothrombin autoantibodies from a V gene phage display library are specific for the kringle 2 domain of prothrombin. Biochemistry. 2004 Apr 6; 43(13):4047-54. PMID: 15049712.
      View in: PubMed
    43. Karle S, Planque S, Nishiyama Y, Taguchi H, Zhou YX, Salas M, Lake D, Thiagarajan P, Arnett F, Hanson CV, Paul S. Cross-clade HIV-1 neutralization by an antibody fragment from a lupus phage display library. AIDS. 2004 Jan 23; 18(2):329-31. PMID: 15075554.
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    44. Merten M, Motamedy S, Ramamurthy S, Arnett FC, Thiagarajan P. Sulfatides: targets for anti-phospholipid antibodies. Circulation. 2003 Oct 28; 108(17):2082-7. PMID: 14530197.
      View in: PubMed
    45. Gushiken FC, Le A, Arnett FC, Thiagarajan P. Polymorphisms beta2-glycoprotein I: phospholipid binding and multimeric structure. Thromb Res. 2002 Nov 1; 108(2-3):175-80. PMID: 12590955.
      View in: PubMed
    46. Thiagarajan P. New targets for antithrombotic drugs. Am J Cardiovasc Drugs. 2002; 2(4):227-35. PMID: 14727968.
      View in: PubMed
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