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ANDREW PATRICK RICE

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Virology & Microbiology
DivisionMolecular Virology & Microbiology
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    R01AI025308     (RICE, ANDREW P)Sep 30, 1987 - Nov 30, 1996
    NIH/NIAID
    MOLECULAR MECHANISM OF TAT TRANS-ACTIVATION
    Role: Principal Investigator

    P30AI036211     (BUTEL, JANET S)Apr 1, 1994 - Jul 31, 2016
    NIH/NIAID
    Baylor-UT Houston Center for AIDS Research
    Role: Co-Principal Investigator

    R01AI035381     (RICE, ANDREW P)Sep 15, 1995 - Feb 28, 2010
    NIH/NIAID
    Mechanisms of HIV-1 latency in CD4+ T lymphocytes
    Role: Principal Investigator

    R21AI045374     (RICE, ANDREW P)Feb 15, 1999 - Jan 31, 2005
    NIH/NIAID
    Regulation of Tak/P-TEFb
    Role: Principal Investigator

    R01AI045374     (RICE, ANDREW P)Feb 15, 1999 - Jan 31, 2011
    NIH/NIAID
    Regulation of Cyclin T1 Protein Expression- Macrophages
    Role: Principal Investigator

    R21AI080222     (RICE, ANDREW P)Mar 1, 2009 - Feb 28, 2012
    NIH/NIAID
    Identification of novel HIV-1 co-factors
    Role: Principal Investigator

    R56AI035381     (RICE, ANDREW P)Sep 22, 2009 - Aug 31, 2011
    NIH/NIAID
    Mechanism of HIV-1 Tat Function
    Role: Principal Investigator

    R21AI083396     (RICE, ANDREW P)May 15, 2010 - Apr 30, 2013
    NIH/NIAID
    Structure and function of influenza A virus PDZ-binding motif
    Role: Principal Investigator

    R21DA030166     (RICE, ANDREW P)Jun 1, 2010 - Mar 31, 2014
    NIH/NIDA
    Effects of cocaine on miRNAs that regulate HIV-1 replication
    Role: Principal Investigator

    R21AI102483     (RICE, ANDREW P)Jul 5, 2012 - Jun 30, 2014
    NIH/NIAID
    Identification of novel co-factors for HIV Tat and Rev as therapeutic targets
    Role: Principal Investigator

    R56AI102754     (RICE, ANDREW P)Jul 17, 2013 - Jun 30, 2014
    NIH/NIAID
    P-TEFb and HIV Latency
    Role: Principal Investigator

    R21AI110263     (RICE, ANDREW P)Jun 1, 2014 - May 31, 2016
    NIH/NIAID
    Mechanisms of Reactivation of Latent HIV by HDAC Inhibitors
    Role: Principal Investigator

    R21AI116173     (RICE, ANDREW P)Sep 1, 2014 - Aug 31, 2016
    NIH/NIAID
    Role of P-TEFB in HIV latency
    Role: Principal Investigator

    R21AI114335     (RICE, ANDREW P)Nov 1, 2014 - Oct 31, 2016
    NIH/NIAID
    Mechanisms of Action of Novel HIV Rev Co-factors
    Role: Principal Investigator

    R21AI124866     (RICE, ANDREW P)Jun 9, 2016 - May 31, 2018
    NIH/NIAID
    Role of NEAT1 lncRNA in HIV replication
    Role: Principal Investigator

    R21AI132001     (RICE, ANDREW P)Jul 15, 2017 - Jun 30, 2019
    NIH/NIAID
    Imaging-base Automated Screen for Compounds that Induce P-TEFb
    Role: Principal Investigator

    R21MH121647     (RICE, ANDREW P)Aug 1, 2019 - Jun 30, 2021
    NIH/NIMH
    Development of Induced-Microglia to Investigate HAND and HIV-1 Latency
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mitra S, Kumar D, Hu L, Sankaran B, Moosa MM, Rice AP, Ferreon JC, Ferreon ACM, Prasad BVV. Influenza A virus protein NS1 exhibits strain-independent conformational plasticity. J Virol. 2019 Aug 02. PMID: 31375595.
      View in: PubMed
    2. Rice AP. Unexpected Mutations in HIV-1 That Confer Resistance to the Tat Inhibitor Didehydro-Cortistatin A. MBio. 2019 Jul 09; 10(4). PMID: 31289189.
      View in: PubMed
    3. Deng N, Ramirez JC, Carey M, Miao H, Arias CA, Rice AP, Wu H. Investigation of temporal and spatial heterogeneities of the immune responses to Bordetella pertussis infection in the lung and spleen of mice via analysis and modeling of dynamic microarray gene expression data. Infect Dis Model. 2019; 4:215-226. PMID: 31236525.
      View in: PubMed
    4. Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE. Erratum for Kirkpatrick et al., "Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections". MBio. 2019 04 02; 10(2). PMID: 30940707.
      View in: PubMed
    5. Couturier J, Orozco AF, Liu H, Budhiraja S, Siwak EB, Nehete PN, Sastry KJ, Rice AP, Lewis DE. Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells. Virol J. 2019 02 20; 16(1):22. PMID: 30786885.
      View in: PubMed
    6. Rice AP. Roles of CDKs in RNA polymerase II transcription of the HIV-1 genome. Transcription. 2019 04; 10(2):111-117. PMID: 30375919.
      View in: PubMed
    7. Liu H, Hu PW, Couturier J, Lewis DE, Rice AP. HIV-1 replication in CD4+ T cells exploits the down-regulation of antiviral NEAT1 long non-coding RNAs following T cell activation. Virology. 2018 09; 522:193-198. PMID: 30036787.
      View in: PubMed
    8. Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE. Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections. MBio. 2018 05 15; 9(3). PMID: 29764948.
      View in: PubMed
    9. Saha JM, Liu H, Hu PW, Nikolai BC, Wu H, Miao H, Rice AP. Proteomic Profiling of a Primary CD4+ T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1. AIDS Res Hum Retroviruses. 2018 01; 34(1):103-110. PMID: 29084447.
      View in: PubMed
    10. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Sep 19; 45(16):9348-9360. PMID: 28637181.
      View in: PubMed
    11. Gui S, Rice AP, Chen R, Wu L, Liu J, Miao H. A scalable algorithm for structure identification of complex gene regulatory network from temporal expression data. BMC Bioinformatics. 2017 Jan 31; 18(1):74. PMID: 28143596.
      View in: PubMed
    12. Rice AP. The HIV-1 Tat Protein: Mechanism of Action and Target for HIV-1 Cure Strategies. Curr Pharm Des. 2017; 23(28):4098-4102. PMID: 28677507.
      View in: PubMed
    13. Kaiser P, Joshi SK, Kim P, Li P, Liu H, Rice AP, Wong JK, Yukl SA. Assays for precise quantification of total (including short) and elongated HIV-1 transcripts. J Virol Methods. 2017 04; 242:1-8. PMID: 28034670.
      View in: PubMed
    14. Rice AP. Cyclin-dependent kinases as therapeutic targets for HIV-1 infection. Expert Opin Ther Targets. 2016 Dec; 20(12):1453-1461. PMID: 27797603.
      View in: PubMed
    15. Kimata JT, Rice AP, Wang J. Challenges and strategies for the eradication of the HIV reservoir. Curr Opin Immunol. 2016 10; 42:65-70. PMID: 27288651.
      View in: PubMed
    16. Jamaluddin MS, Hu PW, Jan Y, Siwak EB, Rice AP. Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb. AIDS Res Hum Retroviruses. 2016 Feb; 32(2):169-73. PMID: 26727990.
      View in: PubMed
    17. Rice AP. Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replication. Wiley Interdiscip Rev RNA. 2015 Nov-Dec; 6(6):661-70. PMID: 26394053.
      View in: PubMed
    18. Rice AP, Kimata JT. Subversion of Cell Cycle Regulatory Mechanisms by HIV. Cell Host Microbe. 2015 Jun 10; 17(6):736-40. PMID: 26067601.
      View in: PubMed
    19. Budhiraja S, Liu H, Couturier J, Malovannaya A, Qin J, Lewis DE, Rice AP. Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function. J Virol. 2015 Apr; 89(7):3557-67. PMID: 25589658.
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    20. Ramakrishnan R, Liu H, Rice AP. Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV. AIDS Res Hum Retroviruses. 2015 Jan; 31(1):137-41. PMID: 24528253.
      View in: PubMed
    21. Carrillo B, Choi JM, Bornholdt ZA, Sankaran B, Rice AP, Prasad BV. The influenza A virus protein NS1 displays structural polymorphism. J Virol. 2014 Apr; 88(8):4113-22. PMID: 24478439.
      View in: PubMed
    22. Budhiraja S, Rice AP. Reactivation of latent HIV: do all roads go through P-TEFb? Future Virol. 2013 Jul 01; 8(7). PMID: 24409197.
      View in: PubMed
    23. Chiang K, Liu H, Rice AP. miR-132 enhances HIV-1 replication. Virology. 2013 Mar 30; 438(1):1-4. PMID: 23357732.
      View in: PubMed
    24. Rice AP. P-TEFb as a target to reactivate latent HIV: two Brds are now in hand. Cell Cycle. 2013 Feb 01; 12(3):392-3. PMID: 23324342.
      View in: PubMed
    25. Budhiraja S, Famiglietti M, Bosque A, Planelles V, Rice AP. Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. J Virol. 2013 Jan; 87(2):1211-20. PMID: 23152527.
      View in: PubMed
    26. Ramakrishnan R, Liu H, Donahue H, Malovannaya A, Qin J, Rice AP. Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function. Retrovirology. 2012 Oct 30; 9:90. PMID: 23110726.
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    27. Chiang K, Rice AP. MicroRNA-mediated restriction of HIV-1 in resting CD4+ T cells and monocytes. Viruses. 2012 09; 4(9):1390-409. PMID: 23170164.
      View in: PubMed
    28. Kumar M, Liu H, Rice AP. Regulation of interferon-ß by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM. PLoS One. 2012; 7(7):e41251. PMID: 22911767.
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    29. Budhiraja S, Ramakrishnan R, Rice AP. Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression. Retrovirology. 2012 Jun 22; 9:52. PMID: 22727189.
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    30. Ramakrishnan R, Chiang K, Liu H, Budhiraja S, Donahue H, Rice AP. Making a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages. Biology (Basel). 2012 Jun 15; 1(1):94-115. PMID: 24832049.
      View in: PubMed
    31. Ramakrishnan R, Rice AP. Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway. J Cell Physiol. 2012 Feb; 227(2):609-17. PMID: 21448926.
      View in: PubMed
    32. Chiang K, Sung TL, Rice AP. Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. J Virol. 2012 Mar; 86(6):3244-52. PMID: 22205749.
      View in: PubMed
    33. Ramakrishnan R, Donahue H, Garcia D, Tan J, Shimizu N, Rice AP, Ling PD. Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas. PLoS One. 2011; 6(11):e27271. PMID: 22102884.
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    34. Golebiewski L, Liu H, Javier RT, Rice AP. The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions. J Virol. 2011 Oct; 85(20):10639-48. PMID: 21849460.
      View in: PubMed
    35. Ramakrishnan R, Yu W, Rice AP. Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1. BMC Res Notes. 2011 Jul 26; 4:260. PMID: 21791050.
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    36. Javier RT, Rice AP. Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses. J Virol. 2011 Nov; 85(22):11544-56. PMID: 21775458.
      View in: PubMed
    37. Chiang K, Rice AP. Mini ways to stop a virus: microRNAs and HIV-1 replication. Future Virol. 2011 Feb; 6(2):209-221. PMID: 21701674.
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    38. Liu H, Golebiewski L, Dow EC, Krug RM, Javier RT, Rice AP. The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. J Virol. 2010 Nov; 84(21):11164-74. PMID: 20702615.
      View in: PubMed
    39. Dow EC, Liu H, Rice AP. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes. J Cell Physiol. 2010 Jul; 224(1):84-93. PMID: 20201073.
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    40. Liu H, Herrmann CH, Chiang K, Sung TL, Moon SH, Donehower LA, Rice AP. 55K isoform of CDK9 associates with Ku70 and is involved in DNA repair. Biochem Biophys Res Commun. 2010 Jun 25; 397(2):245-50. PMID: 20493174.
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    41. Rice AP. The HIV-1 Tat team gets bigger. Cell Host Microbe. 2010 Mar 18; 7(3):179-81. PMID: 20227660.
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    42. Ramakrishnan R, Dow EC, Rice AP. Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes. J Leukoc Biol. 2009 Dec; 86(6):1345-50. PMID: 19741158.
      View in: PubMed
    43. Rice AP. Dysregulation of positive transcription elongation factor B and myocardial hypertrophy. Circ Res. 2009 Jun 19; 104(12):1327-9. PMID: 19542017.
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    44. Yukl S, Pillai S, Li P, Chang K, Pasutti W, Ahlgren C, Havlir D, Strain M, Günthard H, Richman D, Rice AP, Daar E, Little S, Wong JK. Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology. 2009 Apr 25; 387(1):98-108. PMID: 19268337.
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    45. Sung TL, Rice AP. miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1. PLoS Pathog. 2009 Jan; 5(1):e1000263. PMID: 19148268.
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    46. Wang Y, Dow EC, Liang YY, Ramakrishnan R, Liu H, Sung TL, Lin X, Rice AP. Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop. J Biol Chem. 2008 Nov 28; 283(48):33578-84. PMID: 18829461.
      View in: PubMed
    47. Yu W, Ramakrishnan R, Wang Y, Chiang K, Sung TL, Rice AP. Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors. PLoS One. 2008 Sep 05; 3(9):e3146. PMID: 18773076.
      View in: PubMed
    48. Sung TL, Rice AP. Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells. Retrovirology. 2006 Oct 02; 3:66. PMID: 17014716.
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    49. Liu H, Dow EC, Arora R, Kimata JT, Bull LM, Arduino RC, Rice AP. Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genes. J Virol. 2006 Aug; 80(15):7765-8. PMID: 16840357.
      View in: PubMed
    50. Wang Y, Rice AP. Interleukin-10 inhibits HIV-1 LTR-directed gene expression in human macrophages through the induction of cyclin T1 proteolysis. Virology. 2006 Sep 01; 352(2):485-92. PMID: 16781761.
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    51. Yu W, Wang Y, Shaw CA, Qin XF, Rice AP. Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs. Retrovirology. 2006 Jun 09; 3:32. PMID: 16764723.
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    52. Liou LY, Haaland RE, Herrmann CH, Rice AP. Cyclin T1 but not cyclin T2a is induced by a post-transcriptional mechanism in PAMP-activated monocyte-derived macrophages. J Leukoc Biol. 2006 Feb; 79(2):388-96. PMID: 16330531.
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    53. Haaland RE, Herrmann CH, Rice AP. siRNA depletion of 7SK snRNA induces apoptosis but does not affect expression of the HIV-1 LTR or P-TEFb-dependent cellular genes. J Cell Physiol. 2005 Dec; 205(3):463-70. PMID: 16152622.
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    54. Haaland RE, Yu W, Rice AP. Identification of LKLF-regulated genes in quiescent CD4+ T lymphocytes. Mol Immunol. 2005 Mar; 42(5):627-41. PMID: 15607822.
      View in: PubMed
    55. Liou LY, Herrmann CH, Rice AP. HIV-1 infection and regulation of Tat function in macrophages. Int J Biochem Cell Biol. 2004 Sep; 36(9):1767-75. PMID: 15183343.
      View in: PubMed
    56. Liou LY, Herrmann CH, Rice AP. Human immunodeficiency virus type 1 infection induces cyclin T1 expression in macrophages. J Virol. 2004 Aug; 78(15):8114-9. PMID: 15254183.
      View in: PubMed
    57. Haaland RE, Herrmann CH, Rice AP. Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes. AIDS. 2003 Nov 21; 17(17):2429-36. PMID: 14600513.
      View in: PubMed
    58. Rice AP, Herrmann CH. Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages. Curr HIV Res. 2003 Oct; 1(4):395-404. PMID: 15049426.
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    59. Liu H, Yu W, Liou LY, Rice AP. Isolation and characterization of the human DC-SIGN and DC-SIGNR promoters. Gene. 2003 Aug 14; 313:149-59. PMID: 12957386.
      View in: PubMed
    60. Liou LY, Herrmann CH, Rice AP. Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function. J Virol. 2002 Nov; 76(21):10579-87. PMID: 12368300.
      View in: PubMed
    61. Ghose R, Liou LY, Herrmann CH, Rice AP. Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines. J Virol. 2001 Dec; 75(23):11336-43. PMID: 11689614.
      View in: PubMed
    62. Foskett SM, Ghose R, Tang DN, Lewis DE, Rice AP. Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells. J Virol. 2001 Feb; 75(3):1220-8. PMID: 11152495.
      View in: PubMed
    63. Liu H, Rice AP. Isolation and characterization of the human cyclin T1 promoter. Gene. 2000 Jul 11; 252(1-2):39-49. PMID: 10903436.
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    64. Liu H, Rice AP. Genomic organization and characterization of promoter function of the human CDK9 gene. Gene. 2000 Jul 11; 252(1-2):51-9. PMID: 10903437.
      View in: PubMed
    65. Herrmann CH, Carroll RG, Wei P, Jones KA, Rice AP. Tat-associated kinase, TAK, activity is regulated by distinct mechanisms in peripheral blood lymphocytes and promonocytic cell lines. J Virol. 1998 Dec; 72(12):9881-8. PMID: 9811724.
      View in: PubMed
    66. Garber ME, Wei P, KewalRamani VN, Mayall TP, Herrmann CH, Rice AP, Littman DR, Jones KA. The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev. 1998 Nov 15; 12(22):3512-27. PMID: 9832504.
      View in: PubMed
    67. Gold MO, Rice AP. Targeting of CDK8 to a promoter-proximal RNA element demonstrates catalysis-dependent activation of gene expression. Nucleic Acids Res. 1998 Aug 15; 26(16):3784-8. PMID: 9685496.
      View in: PubMed
    68. Gold MO, Yang X, Herrmann CH, Rice AP. PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo. J Virol. 1998 May; 72(5):4448-53. PMID: 9557739.
      View in: PubMed
    69. Yang X, Gold MO, Tang DN, Lewis DE, Aguilar-Cordova E, Rice AP, Herrmann CH. TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12331-6. PMID: 9356449.
      View in: PubMed
    70. Gold MO, Tassan JP, Nigg EA, Rice AP, Herrmann CH. Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic Acids Res. 1996 Oct 01; 24(19):3771-7. PMID: 8871557.
      View in: PubMed
    71. Yang X, Herrmann CH, Rice AP. The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function. J Virol. 1996 Jul; 70(7):4576-84. PMID: 8676484.
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    72. Wang Z, Morris GF, Rice AP, Xiong W, Morris CB. Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Jun 01; 12(2):128-38. PMID: 8680883.
      View in: PubMed
    73. Herrmann CH, Gold MO, Rice AP. Viral transactivators specifically target distinct cellular protein kinases that phosphorylate the RNA polymerase II C-terminal domain. Nucleic Acids Res. 1996 Feb 01; 24(3):501-8. PMID: 8602364.
      View in: PubMed
    74. Aguilar-Cordova E, Chinen J, Donehower LA, Harper JW, Rice AP, Butel JS, Belmont JW. Inhibition of HIV-1 by a double transdominant fusion gene. Gene Ther. 1995 May; 2(3):181-6. PMID: 7614248.
      View in: PubMed
    75. Herrmann CH, Rice AP. Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor. J Virol. 1995 Mar; 69(3):1612-20. PMID: 7853496.
      View in: PubMed
    76. Rhim H, Rice AP. HIV-1 Tat protein is able to efficiently transactivate the HIV-2 LTR through a TAR RNA element lacking both dinucleotide bulge binding sites. Virology. 1995 Jan 10; 206(1):673-8. PMID: 7831824.
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    77. Rhim H, Echetebu CO, Herrmann CH, Rice AP. Wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli as fusions with glutathione S-transferase. J Acquir Immune Defic Syndr. 1994 Nov; 7(11):1116-21. PMID: 7932078.
      View in: PubMed
    78. Rhim H, Rice AP. Exon2 of HIV-2 Tat contributes to transactivation of the HIV-2 LTR by increasing binding affinity to HIV-2 TAR RNA. Nucleic Acids Res. 1994 Oct 25; 22(21):4405-13. PMID: 7971271.
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    79. Rhim H, Rice AP. Functional significance of the dinucleotide bulge in stem-loop1 and stem-loop2 of HIV-2 TAR RNA. Virology. 1994 Jul; 202(1):202-11. PMID: 8009832.
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    80. Echetebu CO, Rhim H, Herrmann CH, Rice AP. Construction and characterization of a potent HIV-2 Tat transdominant mutant protein. J Acquir Immune Defic Syndr. 1994 Jul; 7(7):655-64. PMID: 8207644.
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    81. Herrmann CH, Rice AP. Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase. Virology. 1993 Dec; 197(2):601-8. PMID: 8249283.
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    82. Echetebu CO, Rice AP. Mutational analysis of the amino and carboxy termini of the HIV-2 Tat protein. J Acquir Immune Defic Syndr. 1993 Jun; 6(6):550-7. PMID: 8496787.
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    83. Rice AP, Wilson E, Chan F. Limited proteolytic digestions identify common structural features of HIV-1 Tat proteins expressed during infection from alternatively spliced mRNAs. J Acquir Immune Defic Syndr. 1993 Apr; 6(4):344-52. PMID: 8455140.
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    84. Rhim H, Chan F, Echetebu CO, Rice AP. Rapid purification of monomer HIV-2 Tat protein expressed in Escherichia coli. Protein Expr Purif. 1993 Feb; 4(1):24-31. PMID: 8425105.
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    85. Rhim H, Rice AP. TAR RNA binding properties and relative transactivation activities of human immunodeficiency virus type 1 and 2 Tat proteins. J Virol. 1993 Feb; 67(2):1110-21. PMID: 8419640.
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    86. Rice AP, Chan F. Tat protein of human immunodeficiency virus type 1 is a monomer when expressed in mammalian cells. Virology. 1991 Nov; 185(1):451-4. PMID: 1656598.
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    87. Rice AP, Carlotti F. Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins. J Virol. 1990 Dec; 64(12):6018-26. PMID: 2243385.
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    88. Laspia MF, Rice AP, Mathews MB. Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation. Genes Dev. 1990 Dec; 4(12B):2397-408. PMID: 2149119.
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    89. Gunnery S, Rice AP, Robertson HD, Mathews MB. Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase. Proc Natl Acad Sci U S A. 1990 Nov; 87(22):8687-91. PMID: 2247437.
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    90. Rice AP, Carlotti F. Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type 1 Tat protein. J Virol. 1990 Apr; 64(4):1864-8. PMID: 2181156.
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    91. Rice AP, Kostura M, Mathews MB. Identification of a 90-kDa polypeptide which associates with adenovirus VA RNAI and is phosphorylated by the double-stranded RNA-dependent protein kinase. J Biol Chem. 1989 Dec 05; 264(34):20632-7. PMID: 2584233.
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    92. Laspia MF, Rice AP, Mathews MB. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation. Cell. 1989 Oct 20; 59(2):283-92. PMID: 2553266.
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    93. Rice AP, Mathews MB. Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4200-4. PMID: 2967970.
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    94. Rice AP, Mathews MB. Transcriptional but not translational regulation of HIV-1 by the tat gene product. Nature. 1988 Apr 07; 332(6164):551-3. PMID: 2833703.
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    95. Rice AP, Kerr SM, Roberts WK, Brown RE, Kerr IM. Novel 2',5'-oligoadenylates synthesized in interferon-treated, vaccinia virus-infected cells. J Virol. 1985 Dec; 56(3):1041-4. PMID: 2415713.
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    96. Stroobant P, Rice AP, Gullick WJ, Cheng DJ, Kerr IM, Waterfield MD. Purification and characterization of vaccinia virus growth factor. Cell. 1985 Aug; 42(1):383-93. PMID: 2410141.
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    97. Rice AP, Duncan R, Hershey JW, Kerr IM. Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells. J Virol. 1985 Jun; 54(3):894-8. PMID: 2582150.
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    98. Rice AP, Kerr IM. Interferon-mediated, double-stranded RNA-dependent protein kinase is inhibited in extracts from vaccinia virus-infected cells. J Virol. 1984 Apr; 50(1):229-36. PMID: 6699945.
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    99. Rice AP, Roberts WK, Kerr IM. 2-5A accumulates to high levels in interferon-treated, vaccinia virus-infected cells in the absence of any inhibition of virus replication. J Virol. 1984 Apr; 50(1):220-8. PMID: 6422053.
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    100. Rice AP, Roberts BE. Vaccinia virus induces cellular mRNA degradation. J Virol. 1983 Sep; 47(3):529-39. PMID: 6620463.
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